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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

Journal of medicinal chemistry, 2020-04, Vol.63 (7), p.3538-3551

2020

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Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling

Cells (Basel, Switzerland), 2023-03, Vol.12 (7), p.1066

2023

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One-Pot Synthesis of B‑Ring Ortho-Hydroxylated Sappanin-Type Homoisoflavonoids

Journal of organic chemistry, 2019-06, Vol.84 (11), p.7138-7147

2019

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Aurones: Synthesis and Properties

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2019-05, Vol.55 (4-5), p.285-299

2019

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Carboxylated aurone derivatives as potent inhibitors of xanthine oxidase

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (14), p.3606-3613

2017

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Coumarin-based homoisoflavonoids as precursors in the synthesis of 8-heteroarylmethylcoumarins

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2023-07, Vol.59 (6-7), p.456-464

2023

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Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

Organic & biomolecular chemistry, 2017-09, Vol.15 (36), p.7623-7629

2017

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Carboxylated chalcones and related flavonoids as inhibitors of xanthine oxidase

Medicinal chemistry research, 2023-08, Vol.32 (8), p.1804-1815

2023

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Observations from aminomethylation of 7-substituted 6-hydroxyaurones

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2018-08, Vol.54 (8), p.765-772

2018

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Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

Scientific reports, 2019-04, Vol.9 (1), p.6439-6439, Article 6439

2019

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Chemoselective synthesis of 3-trifluoromethylpyrazole-deoxybenzoin hybrids

Journal of fluorine chemistry, 2021-02, Vol.242, p.109698, Article 109698

2021

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A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho‐Hydroxylated Deoxybenzoins

European journal of organic chemistry, 2018-10, Vol.2018 (39), p.5460-5463

2018

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Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals

Organic & biomolecular chemistry, 2015-01, Vol.13 (4), p.1053-1067

2015

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Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents

Organic & biomolecular chemistry, 2015-12, Vol.13 (46), p.11292-11301

2015

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Synthesis and aminomethylation of regioisomeric 6-hydroxy-4-methyl- and 4-hydroxy-6-methylaurones

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2018-09, Vol.54 (9), p.832-839

2018

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Chemoselective aminomethylation of harmol

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2018-11, Vol.54 (11), p.1061-1064

2018

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Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases

ChemMedChem, 2016-03, Vol.11 (6), p.600-611

2016

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Novel Mycosin Protease MycP1 Inhibitors Identified by Virtual Screening and 4D Fingerprints

Journal of chemical information and modeling, 2014-04, Vol.54 (4), p.1166-1173

2014

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Synthesis of anabasine-containing aminomethyl derivatives of 6-hydroxyaurones

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2019-03, Vol.55 (3), p.212-216

2019

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Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (15), p.3546-3548

2014

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Development of 6H-chromeno[3,4-c]pyrido[3′,2′:4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 secretagogues

Tetrahedron letters, 2015-06, Vol.56 (23), p.3382-3384

2015

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Synthesis and properties of 2-benzylidene-8,9-dihydro-7H-furo[2,3-f][1,3]benzoxazin-3(2H)-one derivatives

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2016-08, Vol.52 (8), p.592-600

2016

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Efficient synthesis of aurone Mannich bases and evaluation of their antineoplastic activity in PC-3 prostate cancer cells

Chemical papers, 2018-10, Vol.72 (10), p.2443-2456

2018

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Inverse electron demand Diels–Alder reactions with aminomethyl derivatives of 3-arylhydroxycoumarins

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2016-07, Vol.52 (7), p.460-466

2016

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A domino reaction for the synthesis of 2H-pyrano-[4″,3″,2″:4′,5′]chromeno[2′,3′:4,5]thieno-[2,3-b]pyridin-2-ones

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2016-04, Vol.52 (4), p.262-266

2016

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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling

One-Pot Synthesis of B‑Ring Ortho-Hydroxylated Sappanin-Type Homoisoflavonoids

Aurones: Synthesis and Properties

Carboxylated aurone derivatives as potent inhibitors of xanthine oxidase

Coumarin-based homoisoflavonoids as precursors in the synthesis of 8-heteroarylmethylcoumarins

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

Carboxylated chalcones and related flavonoids as inhibitors of xanthine oxidase

Observations from aminomethylation of 7-substituted 6-hydroxyaurones

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

Chemoselective synthesis of 3-trifluoromethylpyrazole-deoxybenzoin hybrids

A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho‐Hydroxylated Deoxybenzoins

Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals

Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents

Synthesis and aminomethylation of regioisomeric 6-hydroxy-4-methyl- and 4-hydroxy-6-methylaurones

Chemoselective aminomethylation of harmol

Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases

Novel Mycosin Protease MycP1 Inhibitors Identified by Virtual Screening and 4D Fingerprints

Synthesis of anabasine-containing aminomethyl derivatives of 6-hydroxyaurones

Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease

Development of 6H-chromeno[3,4-c]pyrido[3′,2′:4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 secretagogues

Synthesis and properties of 2-benzylidene-8,9-dihydro-7H-furo[2,3-f][1,3]benzoxazin-3(2H)-one derivatives

Efficient synthesis of aurone Mannich bases and evaluation of their antineoplastic activity in PC-3 prostate cancer cells

Inverse electron demand Diels–Alder reactions with aminomethyl derivatives of 3-arylhydroxycoumarins

A domino reaction for the synthesis of 2H-pyrano-[4″,3″,2″:4′,5′]chromeno[2′,3′:4,5]thieno-[2,3-b]pyridin-2-ones

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