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Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS

Biochemistry (Easton), 2019-02, Vol.58 (6), p.687-696

2019

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Structural evidence for a latch mechanism regulating access to the active site of SufS‐family cysteine desulfurases

Acta crystallographica. Section D, Biological crystallography., 2020-03, Vol.76 (3), p.291-301

2020

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Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues

The Journal of biological chemistry, 2019-08, Vol.294 (33), p.12444-12458

2019

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Improving Functional Annotation in the DRE-TIM Metallolyase Superfamily through Identification of Active Site Fingerprints

Biochemistry (Easton), 2016-03, Vol.55 (12), p.1863-1872

2016

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Chemoenzymatic synthesis of GDP-L-fucose and the Lewis X glycan derivatives

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16096-16101

2009

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Persulfide Transfer to SufE Activates the Half-Sites Reactivity of the E. coli Cysteine Desulfurase SufS

Biochemistry (Easton), 2024-06, Vol.63 (12), p.1569-1577

2024

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HDX-MS Reveals Substrate-Dependent, Localized EX1 Conformational Dynamics in the Retaining GT‑B Glycosyltransferase, MshA

Biochemistry (Easton), 2023-09, Vol.62 (17), p.2645-2657

2023

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Structures and mechanisms of the mycothiol biosynthetic enzymes

Current opinion in chemical biology, 2009-10, Vol.13 (4), p.451-459

2009

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Distinct mechanisms of substrate selectivity in the DRE-TIM metallolyase superfamily: A role for the LeuA dimer regulatory domain

Archives of biochemistry and biophysics, 2019-03, Vol.664, p.1-8

2019

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The structure of the SufS–SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis

The Journal of biological chemistry, 2024-09, Vol.300 (9), p.107641, Article 107641

2024

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Biochemical characterization of 2-phosphinomethylmalate synthase from Streptomyces hygroscopicus: A member of the DRE-TIM metallolyase superfamily

Archives of biochemistry and biophysics, 2020-09, Vol.691, p.108489, Article 108489

2020

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In Vitro and In Silico Explorations of the Protein Conformational Changes of Corynebacterium glutamicum MshA, a Model Retaining GT‑B Glycosyltransferase

Biochemistry (Easton), 2024-04, Vol.63 (7), p.939-951

2024

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The β-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning

The Journal of biological chemistry, 2023-03, Vol.299 (3), p.102966-102966, Article 102966

2023

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Low-molecular-weight chromium-binding substance (LMWCr) may bind and carry Cr(III) from the endosome

Journal of inorganic biochemistry, 2021-10, Vol.223, p.111555-111555, Article 111555

2021

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Structural and functional characterization of α-isopropylmalate synthase and citramalate synthase, members of the LeuA dimer superfamily

Archives of biochemistry and biophysics, 2012-03, Vol.519 (2), p.202-209

Frantom, Patrick A.

2012

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Changes in Protein Dynamics in Escherichia coli SufS Reveal a Possible Conserved Regulatory Mechanism in Type II Cysteine Desulfurase Systems

Biochemistry (Easton), 2018-09, Vol.57 (35), p.5210-5217

2018

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Evolutionarily Distinct Versions of the Multidomain Enzyme α‑Isopropylmalate Synthase Share Discrete Mechanisms of V‑Type Allosteric Regulation

Biochemistry (Easton), 2014-07, Vol.53 (29), p.4847-4856

2014

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Biochemical characterization of the retaining glycosyltransferase glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis

Archives of biochemistry and biophysics, 2014-12, Vol.564, p.120-127

2014

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Structural and Enzymatic Analysis of MshA from Corynebacterium glutamicum: SUBSTRATE-ASSISTED CATALYSIS

The Journal of biological chemistry, 2008-06, Vol.283 (23), p.15834-15844

2008

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Reduction and Oxidation of the Active Site Iron in Tyrosine Hydroxylase: Kinetics and Specificity

Biochemistry (Easton), 2006-02, Vol.45 (7), p.2372-2379

2006

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Direct Spectroscopic Evidence for a High-Spin Fe(IV) Intermediate in Tyrosine Hydroxylase

Journal of the American Chemical Society, 2007-09, Vol.129 (37), p.11334-11335

2007

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Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus

RSC medicinal chemistry, 2023-05, Vol.14 (5), p.947-956

2023

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SufE D74R Substitution Alters Active Site Loop Dynamics To Further Enhance SufE Interaction with the SufS Cysteine Desulfurase

Biochemistry (Easton), 2015-08, Vol.54 (31), p.4824-4833

2015

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Characterization of the genomically encoded fosfomycin resistance enzyme from Mycobacterium abscessus

MedChemComm, 2019-11, Vol.10 (11), p.1948-1957

2019

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Replacing the Traditional Graduate Chemistry Literature Seminar with a Chemical Research Literacy Course

Journal of chemical education, 2016-03, Vol.93 (3), p.482-487

2016

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Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS

Structural evidence for a latch mechanism regulating access to the active site of SufS‐family cysteine desulfurases

Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues

Improving Functional Annotation in the DRE-TIM Metallolyase Superfamily through Identification of Active Site Fingerprints

Chemoenzymatic synthesis of GDP-L-fucose and the Lewis X glycan derivatives

Persulfide Transfer to SufE Activates the Half-Sites Reactivity of the E. coli Cysteine Desulfurase SufS

HDX-MS Reveals Substrate-Dependent, Localized EX1 Conformational Dynamics in the Retaining GT‑B Glycosyltransferase, MshA

Structures and mechanisms of the mycothiol biosynthetic enzymes

Distinct mechanisms of substrate selectivity in the DRE-TIM metallolyase superfamily: A role for the LeuA dimer regulatory domain

The structure of the SufS–SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis

Biochemical characterization of 2-phosphinomethylmalate synthase from Streptomyces hygroscopicus: A member of the DRE-TIM metallolyase superfamily

In Vitro and In Silico Explorations of the Protein Conformational Changes of Corynebacterium glutamicum MshA, a Model Retaining GT‑B Glycosyltransferase

The β-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning

Low-molecular-weight chromium-binding substance (LMWCr) may bind and carry Cr(III) from the endosome

Structural and functional characterization of α-isopropylmalate synthase and citramalate synthase, members of the LeuA dimer superfamily

Changes in Protein Dynamics in Escherichia coli SufS Reveal a Possible Conserved Regulatory Mechanism in Type II Cysteine Desulfurase Systems

Evolutionarily Distinct Versions of the Multidomain Enzyme α‑Isopropylmalate Synthase Share Discrete Mechanisms of V‑Type Allosteric Regulation

Biochemical characterization of the retaining glycosyltransferase glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis

Structural and Enzymatic Analysis of MshA from Corynebacterium glutamicum: SUBSTRATE-ASSISTED CATALYSIS

Reduction and Oxidation of the Active Site Iron in Tyrosine Hydroxylase: Kinetics and Specificity

Direct Spectroscopic Evidence for a High-Spin Fe(IV) Intermediate in Tyrosine Hydroxylase

Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus

SufE D74R Substitution Alters Active Site Loop Dynamics To Further Enhance SufE Interaction with the SufS Cysteine Desulfurase

Characterization of the genomically encoded fosfomycin resistance enzyme from Mycobacterium abscessus

Replacing the Traditional Graduate Chemistry Literature Seminar with a Chemical Research Literacy Course

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