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Structural Basis for the Inhibition of Firefly Luciferase by a General Anesthetic

Biophysical journal, 1998-11, Vol.75 (5), p.2205-2211

1998

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Neurons in prefrontal cortex respond to sleep deprivation by initiating sleep preparatory behaviour and NREM sleep

Sleep medicine, 2022-12, Vol.100, p.S20

2022

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Xenon is neuroprotective against blast traumatic brain injury in vitro

British journal of anaesthesia : BJA, 2018-08, Vol.121 (2), p.e23-e23

2018

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Xenon treatment improves short-term and long-term outcomes in a rodent model of traumatic brain injury

British journal of anaesthesia : BJA, 2018-08, Vol.121 (2), p.e21-e21

2018

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Neuroprotective and neurotoxic properties of the ‘inert’ gas, xenon

British journal of anaesthesia : BJA, 2002-11, Vol.89 (5), p.739-746

2002

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Xenon: no stranger to anaesthesia

British journal of anaesthesia : BJA, 2003-11, Vol.91 (5), p.709-717

2003

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Molecular Organization of Liquid n-Octanol: An X-ray Diffraction Analysis

Journal of pharmaceutical sciences, 1993-05, Vol.82 (5), p.466-470

1993

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Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat

British journal of anaesthesia : BJA, 2007-02, Vol.98 (2), p.236-240

2007

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The effects of general anaesthetics on carbachol-evoked gamma oscillations in the rat hippocampus in vitro

Neuropharmacology, 2003-06, Vol.44 (7), p.864-872

2003

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Which molecular targets are most relevant to general anaesthesia?

Toxicology letters, 1998-11, Vol.100 (1-3), p.1-8

1998

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Structural analysis of hydrated egg lecithin and cholesterol bilayers I. X-ray diffraction

Journal of molecular biology, 1976-01, Vol.100 (3), p.345-358

Franks, N.P.

1976

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Anesthetic inhibition of firefly luciferase, a protein model for general anesthesia, does not exhibit pressure reversal

Biophysical journal, 1991-12, Vol.60 (6), p.1309-1314

1991

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Effects of isoflurane and xenon on Ba 2+ -currents mediated by N-type calcium channels † †Declaration of interest. Professor Franks is a board member of an Imperial College spin-out company, Protexeon Ltd, that is interested in developing clinical applications for medical gases, including xenon. Professor Franks is a paid consultant in this activity. In addition Air Products have funded work in the authors’ laboratories that bears on the actions of xenon as an anaesthetic and neuroprotectant. Ai

British journal of anaesthesia : BJA, 2005-06, Vol.94 (6), p.784-790

2005

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Effects of isoflurane and xenon on Ba2+-currents mediated by N-type calcium channels††Declaration of interest. Professor Franks is a board member of an Imperial College spin-out company, Protexeon Ltd, that is interested in developing clinical applications for medical gases, including xenon. Professor Franks is a paid consultant in this activity. In addition Air Products have funded work in the authors’ laboratories that bears on the actions of xenon as an anaesthetic and neuroprotectant. Air Pr

British journal of anaesthesia : BJA, 2005-06, Vol.94 (6), p.784-790

2005

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Structural analysis of hydrated egg lecithin and cholesterol bilayers II. Neutron diffraction

Journal of molecular biology, 1976-01, Vol.100 (3), p.359-378

1976

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Stereospecific Effects of Inhalational General Anesthetic Optical Isomers on Nerve Ion Channels

Science (American Association for the Advancement of Science), 1991-10, Vol.254 (5030), p.427-430

1991

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SELECTIVE ACTIONS OF VOLATILE GENERAL ANAESTHETICS AT MOLECULAR AND CELLULAR LEVELS

British Journal of Anaesthesia, 1993-07, Vol.71 (1), p.65-76

1993

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Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes

British journal of pharmacology, 1996-06, Vol.118 (3), p.493-502

1996

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Actions of general anaesthetics on 5‐HT3 receptors in N1E‐115 neuroblastoma cells

British journal of pharmacology, 1996-04, Vol.117 (7), p.1507-1515

1996

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Stereoselective and non‐stereoselective actions of isoflurane on the GABA A receptor

British journal of pharmacology, 1994-07, Vol.112 (3), p.906-910

1994

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Stereoselective and non‐stereoselective actions of isoflurane on the GABAA receptor

British journal of pharmacology, 1994-07, Vol.112 (3), p.906-910

1994

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Can the stereoselective effects of the anesthetic isoflurane be accounted for by lipid solubility?

Biophysical journal, 1994-06, Vol.66 (6), p.2019-2023

1994

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Actions of general anaesthetics on a neuronal nicotinic acetylcholine receptor in isolated identified neurones of Lymnaea stagnalis

British journal of pharmacology, 1995-05, Vol.115 (2), p.275-282

1995

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What is the molecular nature of general anaesthetic target sites?

Trends in pharmacological sciences (Regular ed.), 1987-05, Vol.8 (5), p.169-174

1987

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Thermodynamics of anesthetic/protein interactions. Temperature studies on firefly luciferase

Biophysical journal, 1993-04, Vol.64 (4), p.1264-1271

1993

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Structural Basis for the Inhibition of Firefly Luciferase by a General Anesthetic

Neurons in prefrontal cortex respond to sleep deprivation by initiating sleep preparatory behaviour and NREM sleep

Xenon is neuroprotective against blast traumatic brain injury in vitro

Xenon treatment improves short-term and long-term outcomes in a rodent model of traumatic brain injury

Neuroprotective and neurotoxic properties of the ‘inert’ gas, xenon

Xenon: no stranger to anaesthesia

Molecular Organization of Liquid n-Octanol: An X-ray Diffraction Analysis

Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal rat

The effects of general anaesthetics on carbachol-evoked gamma oscillations in the rat hippocampus in vitro

Which molecular targets are most relevant to general anaesthesia?

Structural analysis of hydrated egg lecithin and cholesterol bilayers I. X-ray diffraction

Anesthetic inhibition of firefly luciferase, a protein model for general anesthesia, does not exhibit pressure reversal

Structural analysis of hydrated egg lecithin and cholesterol bilayers II. Neutron diffraction

Stereospecific Effects of Inhalational General Anesthetic Optical Isomers on Nerve Ion Channels

SELECTIVE ACTIONS OF VOLATILE GENERAL ANAESTHETICS AT MOLECULAR AND CELLULAR LEVELS

Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes

Actions of general anaesthetics on 5‐HT3 receptors in N1E‐115 neuroblastoma cells

Stereoselective and non‐stereoselective actions of isoflurane on the GABA A receptor

Stereoselective and non‐stereoselective actions of isoflurane on the GABAA receptor

Can the stereoselective effects of the anesthetic isoflurane be accounted for by lipid solubility?

Actions of general anaesthetics on a neuronal nicotinic acetylcholine receptor in isolated identified neurones of Lymnaea stagnalis

What is the molecular nature of general anaesthetic target sites?

Thermodynamics of anesthetic/protein interactions. Temperature studies on firefly luciferase

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