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Synthesis of (±)‐Physovenine through Electrochemical C−O Bond Formation

European journal of organic chemistry, 2022-12, Vol.2022 (47), p.n/a

2022

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Practical Electrochemical Anodic Oxidation of Polycyclic Lactams for Late Stage Functionalization

Angewandte Chemie (International ed.), 2015-09, Vol.54 (36), p.10555-10558

International ed. in English, 2015

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Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36703-36716

2013

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Structure-Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase

ChemMedChem, 2013-02, Vol.8 (2), p.297-312

2013

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Divergent Electrochemical Carboamidation of Cyclic Amines

Journal of organic chemistry, 2022-01, Vol.87 (2), p.1173-1193

2022

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Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

Nucleic acids research, 2012-09, Vol.40 (17), p.8607-8621

2012

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Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids

Autophagy, 2016-09, Vol.12 (9), p.1460-1471

2016

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High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors

ACS combinatorial science, 2015-10, Vol.17 (10), p.641-652

2015

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Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (17), p.6727-6732

2011

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Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor

Frontiers in synaptic neuroscience, 2018-02, Vol.10, p.2-2

2018

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AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer's & dementia : translational research & clinical interventions, 2022, Vol.8 (1), p.e12246-n/a

2022

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Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology

Alzheimer's & dementia : translational research & clinical interventions, 2022, Vol.8 (1), p.e12253-n/a

2022

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Grubbs' Catalyst in Paraffin: An Air-Stable Preparation for Alkene Metathesis

Journal of organic chemistry, 2003-07, Vol.68 (15), p.6047-6048

2003

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Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus

Neuropharmacology, 2015-12, Vol.99, p.600-609

2015

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Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist

Journal of medicinal chemistry, 2020-05, Vol.63 (10), p.5526-5567

2020

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Identification of Positive Allosteric Modulators of the D 1 Dopamine Receptor That Act at Diverse Binding Sites

Molecular pharmacology, 2018-10, Vol.94 (4), p.1197-1209

2018

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Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D 3 Dopamine Receptor Agonist

Journal of medicinal chemistry, 2020-05, Vol.63 (10), p.5526-5567

2020

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Chemotype-selective Modes of Action of κ-Opioid Receptor Agonists

The Journal of biological chemistry, 2013-11, Vol.288 (48), p.34470-34483

2013

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Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis

Science translational medicine, 2018-05, Vol.10 (441)

2018

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Development of pyrimidone D1 dopamine receptor positive allosteric modulators

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127696-127696, Article 127696

2021

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Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples

Bioorganic & medicinal chemistry letters, 2016-12, Vol.26 (23), p.5689-5694

2016

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Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction

Journal of the American Chemical Society, 2008-05, Vol.130 (18), p.6018-6024

2008

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Structure–Activity Relationships of a Negative Allosteric Modulator of the D3 Dopamine Receptor and Investigation of its Binding Site

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting

Neuropharmacology, 2015-12, Vol.99, p.131-141

2015

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Synthesis of (±)‐Physovenine through Electrochemical C−O Bond Formation

Practical Electrochemical Anodic Oxidation of Polycyclic Lactams for Late Stage Functionalization

Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors

Structure-Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase

Divergent Electrochemical Carboamidation of Cyclic Amines

Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids

High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors

Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands

Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology

Grubbs' Catalyst in Paraffin: An Air-Stable Preparation for Alkene Metathesis

Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus

Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist

Identification of Positive Allosteric Modulators of the D 1 Dopamine Receptor That Act at Diverse Binding Sites

Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D 3 Dopamine Receptor Agonist

Chemotype-selective Modes of Action of κ-Opioid Receptor Agonists

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis

Development of pyrimidone D1 dopamine receptor positive allosteric modulators

Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples

Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction

Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis

Structure–Activity Relationships of a Negative Allosteric Modulator of the D3 Dopamine Receptor and Investigation of its Binding Site

Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting

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