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Signal transduction mediated by the Ras Raf MEK ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention

Leukemia, 2003-07, Vol.17 (7), p.1263-1293

2003

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Kinases : positive and negative regulators of apoptosis

Leukemia, 2000-12, Vol.14 (12), p.2019-2034

2000

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JAK STAT, Raf MEK ERK, PI3K Akt and BCR-ABL in cell cycle progression and leukemogenesis

Leukemia, 2004-02, Vol.18 (2), p.189-218

2004

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Involvement of PI3K Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy

Leukemia, 2003-03, Vol.17 (3), p.590-603

2003

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Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

Leukemia, 1998-12, Vol.12 (12), p.1903-1929

1998

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Redox Regulation of the Calcium/Calmodulin-dependent Protein Kinases

The Journal of biological chemistry, 2004-10, Vol.279 (43), p.44573-44581

2004

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Calcium/calmodulin-dependent kinase I and calcium/calmodulin- dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells

Cancer research (Chicago, Ill.), 2005-06, Vol.65 (12), p.5408-5416

2005

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Effects of the RAF MEK ERK and PI3K AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells

Oncogene, 2003-04, Vol.22 (16), p.2478-2492

2003

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Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells : possible sites for intervention with anti-neoplastic drugs

Leukemia, 1999-08, Vol.13 (8), p.1109-1166

1999

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Role of the Raf Signal Transduction Cascade in the in Vitro Resistance to the Anticancer Drug Doxorubicin

Clinical cancer research, 2001-09, Vol.7 (9), p.2898-2907

2001

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The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what's genetics got to do with it?

Expert opinion on therapeutic targets, 2005-10, Vol.9 (5), p.1009-1030

2005

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Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation

Leukemia, 2003-09, Vol.17 (9), p.1765-1782

2003

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Requirement for the PI3K Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia

Leukemia, 2003-06, Vol.17 (6), p.1058-1067

2003

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Participation of the Calcium/Calmodulin-dependent Kinases in Hydrogen Peroxide-induced IκB Phosphorylation in Human T Lymphocytes

The Journal of biological chemistry, 2002-08, Vol.277 (34), p.30469-30476

2002

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Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

Leukemia, 2000-04, Vol.14 (4), p.642-656

2000

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Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy

Expert opinion on therapeutic targets, 2005-08, Vol.9 (4), p.791-808

2005

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A conditionally-active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells

Oncogene, 2000-01, Vol.19 (4), p.526-536

2000

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Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells

Oncogene, 2004-10, Vol.23 (47), p.7810-7820

2004

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Conditional EGFR Promotes Cell Cycle Progression and Prevention of Apoptosis in the Absence of Autocrine Cytokines

Cell cycle (Georgetown, Tex.), 2005-06, Vol.4 (6), p.822-830

2005

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Inhibition of CREB transcriptional activity in human T lymphocytes by oxidative stress

Free radical biology & medicine, 2005-06, Vol.38 (12), p.1653-1661

2005

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Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase

Molecular immunology, 2000-08, Vol.37 (11), p.675-683

2000

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B-raf and insulin synergistically prevent apoptosis and induce cell cycle progression in hematopoietic cells

Cell cycle (Georgetown, Tex.), 2004-02, Vol.3 (2), p.189-196

2004

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Effects of Endogenous Epidermal Growth Factor Receptor Signaling on DNA Synthesis and ERK Activation in a Cytokine-Dependent Hematopoietic Cell Line

Cell cycle (Georgetown, Tex.), 2005-06, Vol.4 (6), p.818-821

2005

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Two targets are better than one, Promising combination therapy to treat breast cancer

Cancer biology & therapy, 2005-11, Vol.4 (11), p.1190-1191

2005

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Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes

The Journal of clinical investigation, 1994-05, Vol.93 (5), p.2134-2140

1994

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Signal transduction mediated by the Ras Raf MEK ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention

Kinases : positive and negative regulators of apoptosis

JAK STAT, Raf MEK ERK, PI3K Akt and BCR-ABL in cell cycle progression and leukemogenesis

Involvement of PI3K Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy

Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

Redox Regulation of the Calcium/Calmodulin-dependent Protein Kinases

Calcium/calmodulin-dependent kinase I and calcium/calmodulin- dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells

Effects of the RAF MEK ERK and PI3K AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells : possible sites for intervention with anti-neoplastic drugs

Role of the Raf Signal Transduction Cascade in the in Vitro Resistance to the Anticancer Drug Doxorubicin

The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what's genetics got to do with it?

Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation

Requirement for the PI3K Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia

Participation of the Calcium/Calmodulin-dependent Kinases in Hydrogen Peroxide-induced IκB Phosphorylation in Human T Lymphocytes

Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy

A conditionally-active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells

Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells

Conditional EGFR Promotes Cell Cycle Progression and Prevention of Apoptosis in the Absence of Autocrine Cytokines

Inhibition of CREB transcriptional activity in human T lymphocytes by oxidative stress

Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase

B-raf and insulin synergistically prevent apoptosis and induce cell cycle progression in hematopoietic cells

Effects of Endogenous Epidermal Growth Factor Receptor Signaling on DNA Synthesis and ERK Activation in a Cytokine-Dependent Hematopoietic Cell Line

Two targets are better than one, Promising combination therapy to treat breast cancer

Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes

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