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The role of saliva in tick feeding

Frontiers in bioscience (Landmark. Print), 2009-01, Vol.14 (6), p.2051-2088

2009

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Tick salivary secretion as a source of antihemostatics

Journal of proteomics, 2012-07, Vol.75 (13), p.3842-3854

2012

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Antiinflammatory and Immunosuppressive Activity of Sialostatin L, a Salivary Cystatin from the Tick Ixodes scapularis

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26298-26307

2006

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Does activation of the blood coagulation cascade have a role in malaria pathogenesis?

Trends in parasitology, 2008-06, Vol.24 (6), p.258-263

Francischetti, Ivo M.B

2008

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Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate

Arteriosclerosis, thrombosis, and vascular biology, 2013-12, Vol.33 (12), p.2759

2013

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Inhibition of tissue factor by ixolaris reduces primary tumor growth and experimental metastasis in a murine model of melanoma

Thrombosis research, 2012-09, Vol.130 (3), p.e163-e170

2012

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Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick–Host Interactions

Trends in parasitology, 2016-03, Vol.32 (3), p.242-254

2016

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Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood–brain barrier damage, and inflammation

Brain, behavior, and immunity, 2021-03, Vol.93, p.288-298

2021

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Platelet aggregation inhibitors from hematophagous animals

Toxicon (Oxford), 2010-12, Vol.56 (7), p.1130-1144

Francischetti, Ivo M.B.

2010

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Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

EClinicalMedicine, 2021-09, Vol.39, p.101069-101069, Article 101069

2021

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Idiopathic anaphylaxis and systemic mastocytosis

International journal of hematology, 2019-12, Vol.110 (6), p.643-644

2019

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CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes

PLoS pathogens, 2020-08, Vol.16 (8), p.e1008230-e1008230

2020

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Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis

Scientific reports, 2018-03, Vol.8 (1), p.4806-12, Article 4806

2018

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Sexual differences in the sialomes of the zebra tick, Rhipicephalus pulchellus

Journal of proteomics, 2015-03, Vol.117, p.120-144

2015

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Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo

Arteriosclerosis, thrombosis, and vascular biology, 2012-09, Vol.32 (9), p.2185

2012

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Laboratory and clinical predictors of 30-day survival for patients on Extracorporeal Membrane Oxygenation (ECMO): 8-Year experience at Albert Einstein College of Medicine, Montefiore Medical Center

Journal of critical care, 2017-08, Vol.40, p.136-144

2017

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In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

PLoS neglected tropical diseases, 2016-01, Vol.10 (1), p.e0004298-e0004298

2016

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Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis

PLoS pathogens, 2014-09, Vol.10 (9), p.e1004338-e1004338

2014

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The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food

Insect biochemistry and molecular biology, 2012-05, Vol.42 (5), p.332-342

2012

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Aegyptin inhibits collagen-induced coagulation activation in vitro and thromboembolism in vivo

Biochemical and biophysical research communications, 2013-06, Vol.436 (2), p.235-239

2013

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Comparative sialomics between hard and soft ticks: Implications for the evolution of blood-feeding behavior

Insect biochemistry and molecular biology, 2008-01, Vol.38 (1), p.42-58

2008

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The “Vampirome”: Transcriptome and proteome analysis of the principal and accessory submaxillary glands of the vampire bat Desmodus rotundus, a vector of human rabies

Journal of proteomics, 2013-04, Vol.82, p.288-319

2013

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Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis

Biochemical and biophysical research communications, 2003-06, Vol.305 (4), p.869-875

2003

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Dipetalodipin, a Novel Multifunctional Salivary Lipocalin That Inhibits Platelet Aggregation, Vasoconstriction, and Angiogenesis through Unique Binding Specificity for TXA2, PGF2α, and 15(S)-HETE

The Journal of biological chemistry, 2010-12, Vol.285 (50), p.39001-39012

2010

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Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo

The FEBS journal, 2010, Vol.277 (2), p.413-427

2010

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The role of saliva in tick feeding

Tick salivary secretion as a source of antihemostatics

Antiinflammatory and Immunosuppressive Activity of Sialostatin L, a Salivary Cystatin from the Tick Ixodes scapularis

Does activation of the blood coagulation cascade have a role in malaria pathogenesis?

Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate

Inhibition of tissue factor by ixolaris reduces primary tumor growth and experimental metastasis in a murine model of melanoma

Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick–Host Interactions

Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood–brain barrier damage, and inflammation

Platelet aggregation inhibitors from hematophagous animals

Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

Idiopathic anaphylaxis and systemic mastocytosis

CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes

Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis

Sexual differences in the sialomes of the zebra tick, Rhipicephalus pulchellus

Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo

Laboratory and clinical predictors of 30-day survival for patients on Extracorporeal Membrane Oxygenation (ECMO): 8-Year experience at Albert Einstein College of Medicine, Montefiore Medical Center

In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis

The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food

Aegyptin inhibits collagen-induced coagulation activation in vitro and thromboembolism in vivo

Comparative sialomics between hard and soft ticks: Implications for the evolution of blood-feeding behavior

The “Vampirome”: Transcriptome and proteome analysis of the principal and accessory submaxillary glands of the vampire bat Desmodus rotundus, a vector of human rabies

Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis

Dipetalodipin, a Novel Multifunctional Salivary Lipocalin That Inhibits Platelet Aggregation, Vasoconstriction, and Angiogenesis through Unique Binding Specificity for TXA2, PGF2α, and 15(S)-HETE

Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo

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