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Platelet aggregation inhibitors from hematophagous animals

Toxicon (Oxford), 2010-12, Vol.56 (7), p.1130-1144

Francischetti, Ivo M.B.

2010

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A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

Blood, 2011-01, Vol.117 (2), p.736-744

2011

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ROLE OF ARTHROPOD SALIVA IN BLOOD FEEDING: Sialome and Post-Sialome Perspectives

Annual review of entomology, 2003-01, Vol.48 (1), p.73-88

2003

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Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica

PLoS neglected tropical diseases, 2016-07, Vol.10 (7), p.e0004771-e0004771

2016

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Evidence for a lectin specific for sulfated glycans in the salivary gland of the malaria vector, Anopheles gambiae

PloS one, 2014-09, Vol.9 (9), p.e107295

2014

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Antiinflammatory and Immunosuppressive Activity of Sialostatin L, a Salivary Cystatin from the Tick Ixodes scapularis

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26298-26307

2006

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Simukunin from the salivary glands of the black fly Simulium vittatum inhibits enzymes that regulate clotting and inflammatory responses

PloS one, 2012-02, Vol.7 (2), p.e29964

2012

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Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria

PloS one, 2014-02, Vol.9 (2), p.e87140-e87140

2014

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A Deep Insight into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera)

Journal of medical entomology, 2015-05, Vol.52 (3), p.351-358

2015

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An updated catalogue of salivary gland transcripts in the adult female mosquito, Anopheles gambiae

Journal of experimental biology, 2005-10, Vol.208 (Pt 20), p.3971-3986

2005

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The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite

PLoS biology, 2010-11, Vol.8 (11), p.e1000547

2010

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Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex

Blood, 2002-05, Vol.99 (10), p.3602-3612

2002

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Cutting Edge: Immunity against a "Silent" Salivary Antigen of the Lyme Vector Ixodes scapularis Impairs Its Ability to Feed

The Journal of immunology (1950), 2008-10, Vol.181 (8), p.5209-5212

2008

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An insight into the sialotranscriptome of the cat flea, Ctenocephalides felis

PloS one, 2012-09, Vol.7 (9), p.e44612-e44612

2012

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Exploring the sialome of the tick Ixodes scapularis

Journal of experimental biology, 2002-09, Vol.205 (Pt 18), p.2843-2864

2002

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An insight into the sialotranscriptome and proteome of the coarse bontlegged tick, Hyalomma marginatum rufipes

Journal of proteomics, 2011-11, Vol.74 (12), p.2892-2908

2011

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Evolutionarily conserved interaction between the phosphoproteins and X proteins of bornaviruses from different vertebrate species

PloS one, 2012-12, Vol.7 (12), p.e51161-e51161

2012

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Penthalaris, a novel recombinant five-Kunitz tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick vector of Lyme disease, Ixodes scapularis

Thrombosis and haemostasis, 2004-05, Vol.91 (5), p.886-898

2004

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Tick salivary secretion as a source of antihemostatics

Journal of proteomics, 2012-07, Vol.75 (13), p.3842-3854

2012

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Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5429-5434

2012

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Anticoagulant activity of a sulfated galactan: serpin-independent effect and specific interaction with factor Xa

Thrombosis and haemostasis, 2009-12, Vol.102 (6), p.1183-1193

2009

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An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks

Insect biochemistry and molecular biology, 2006-02, Vol.36 (2), p.111-129

2006

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An Insight Into the Sialotranscriptome of Triatoma rubida (Hemiptera: Heteroptera)

Journal of medical entomology, 2012-05, Vol.49 (3), p.563-572

2012

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Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo

Arteriosclerosis, thrombosis, and vascular biology, 2012-09, Vol.32 (9), p.2185-2198

2012

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In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

PLoS neglected tropical diseases, 2016-01, Vol.10 (1), p.e0004298-e0004298

2016

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Platelet aggregation inhibitors from hematophagous animals

A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

ROLE OF ARTHROPOD SALIVA IN BLOOD FEEDING: Sialome and Post-Sialome Perspectives

Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica

Evidence for a lectin specific for sulfated glycans in the salivary gland of the malaria vector, Anopheles gambiae

Antiinflammatory and Immunosuppressive Activity of Sialostatin L, a Salivary Cystatin from the Tick Ixodes scapularis

Simukunin from the salivary glands of the black fly Simulium vittatum inhibits enzymes that regulate clotting and inflammatory responses

Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria

A Deep Insight into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera)

An updated catalogue of salivary gland transcripts in the adult female mosquito, Anopheles gambiae

The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite

Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex

Cutting Edge: Immunity against a "Silent" Salivary Antigen of the Lyme Vector Ixodes scapularis Impairs Its Ability to Feed

An insight into the sialotranscriptome of the cat flea, Ctenocephalides felis

Exploring the sialome of the tick Ixodes scapularis

An insight into the sialotranscriptome and proteome of the coarse bontlegged tick, Hyalomma marginatum rufipes

Evolutionarily conserved interaction between the phosphoproteins and X proteins of bornaviruses from different vertebrate species

Penthalaris, a novel recombinant five-Kunitz tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick vector of Lyme disease, Ixodes scapularis

Tick salivary secretion as a source of antihemostatics

Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P

Anticoagulant activity of a sulfated galactan: serpin-independent effect and specific interaction with factor Xa

An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks

An Insight Into the Sialotranscriptome of Triatoma rubida (Hemiptera: Heteroptera)

Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo

In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

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