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Platelet aggregation inhibitors from hematophagous animals

Toxicon (Oxford), 2010-12, Vol.56 (7), p.1130-1144

Francischetti, Ivo M.B.

2010

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The role of saliva in tick feeding

Frontiers in bioscience, 2009-01, Vol.14 (6), p.2051

2009

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Tick salivary secretion as a source of antihemostatics

Journal of proteomics, 2012-07, Vol.75 (13), p.3842-3854

2012

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Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick–Host Interactions

Trends in parasitology, 2016-03, Vol.32 (3), p.242-254

2016

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Antiinflammatory and Immunosuppressive Activity of Sialostatin L, a Salivary Cystatin from the Tick Ixodes scapularis

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26298-26307

2006

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Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica

PLoS neglected tropical diseases, 2016-07, Vol.10 (7), p.e0004771-e0004771

2016

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A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism

Blood, 2023-06, Vol.141 (25), p.3109-3121

2023

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A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

Blood, 2011-01, Vol.117 (2), p.736-744

2011

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further insight into the sialome of the tropical bont tick, Amblyomma variegatum

BMC genomics, 2011-03, Vol.12 (1), p.136-136, Article 136

2011

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ROLE OF ARTHROPOD SALIVA IN BLOOD FEEDING: Sialome and Post-Sialome Perspectives

Annual review of entomology, 2003-01, Vol.48 (1), p.73-88

2003

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Modulation of host immunity by tick saliva

Journal of proteomics, 2015-10, Vol.128, p.58-68

2015

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Evidence for a lectin specific for sulfated glycans in the salivary gland of the malaria vector, Anopheles gambiae

PloS one, 2014-09, Vol.9 (9), p.e107295

2014

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Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood–brain barrier damage, and inflammation

Brain, behavior, and immunity, 2021-03, Vol.93, p.288-298

2021

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In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

PLoS neglected tropical diseases, 2016-01, Vol.10 (1), p.e0004298-e0004298

2016

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Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy

Science translational medicine, 2017-08, Vol.9 (405)

2017

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Does activation of the blood coagulation cascade have a role in malaria pathogenesis?

Trends in parasitology, 2008-06, Vol.24 (6), p.258-263

Francischetti, Ivo M.B

2008

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Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

EClinicalMedicine, 2021-09, Vol.39, p.101069-101069, Article 101069

2021

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CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes

PLoS pathogens, 2020-08, Vol.16 (8), p.e1008230-e1008230

2020

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Idiopathic anaphylaxis and systemic mastocytosis

International journal of hematology, 2019-12, Vol.110 (6), p.643-644

2019

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Simukunin from the salivary glands of the black fly Simulium vittatum inhibits enzymes that regulate clotting and inflammatory responses

PloS one, 2012-02, Vol.7 (2), p.e29964

2012

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Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo

Arteriosclerosis, thrombosis, and vascular biology, 2012-09, Vol.32 (9), p.2185-2198

2012

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Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis

PLoS pathogens, 2014-09, Vol.10 (9), p.e1004338-e1004338

2014

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Hairy cell leukemia coexistent with chronic lymphocytic leukemia

Blood, 2019-03, Vol.133 (11), p.1264-1264

2019

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The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite

PLoS biology, 2010-11, Vol.8 (11), p.e1000547

2010

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A Deep Insight into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera)

Journal of medical entomology, 2015-05, Vol.52 (3), p.351-358

2015

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Platelet aggregation inhibitors from hematophagous animals

The role of saliva in tick feeding

Tick salivary secretion as a source of antihemostatics

Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick–Host Interactions

Antiinflammatory and Immunosuppressive Activity of Sialostatin L, a Salivary Cystatin from the Tick Ixodes scapularis

Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica

A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism

A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

further insight into the sialome of the tropical bont tick, Amblyomma variegatum

ROLE OF ARTHROPOD SALIVA IN BLOOD FEEDING: Sialome and Post-Sialome Perspectives

Modulation of host immunity by tick saliva

Evidence for a lectin specific for sulfated glycans in the salivary gland of the malaria vector, Anopheles gambiae

Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood–brain barrier damage, and inflammation

In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy

Does activation of the blood coagulation cascade have a role in malaria pathogenesis?

Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes

Idiopathic anaphylaxis and systemic mastocytosis

Simukunin from the salivary glands of the black fly Simulium vittatum inhibits enzymes that regulate clotting and inflammatory responses

Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo

Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis

Hairy cell leukemia coexistent with chronic lymphocytic leukemia

The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite

A Deep Insight into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera)

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