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Sensing and reacting to microbes through the inflammasomes

Nature immunology, 2012-04, Vol.13 (4), p.325-332

2012

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Role of inflammasomes in intestinal inflammation and Crohn's disease

Inflammatory bowel diseases, 2015-01, Vol.21 (1), p.173-181

2015

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Function of Nod-like receptors in microbial recognition and host defense

Immunological reviews, 2009-01, Vol.227 (1), p.106-128

2009

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The protein kinase PKR is critical for LPS‐induced iNOS production but dispensable for inflammasome activation in macrophages

European journal of immunology, 2013-05, Vol.43 (5), p.1147-1152

2013

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A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome

The Journal of immunology (1950), 2009-09, Vol.183 (6), p.3942-3948

2009

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Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux

The Journal of immunology (1950), 2014-10, Vol.193 (8), p.4214-4222

2014

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The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

Immunity (Cambridge, Mass.), 2011-05, Vol.34 (5), p.769-780

2011

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STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria

Molecular immunology, 2009-05, Vol.46 (8), p.1867-1877

2009

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RNase L Activates the NLRP3 Inflammasome during Viral Infections

Cell host & microbe, 2015-04, Vol.17 (4), p.466-477

2015

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Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ

PLoS pathogens, 2014-02, Vol.10 (2), p.e1003926-e1003926

2014

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Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (40), p.E4254-E4263

2014

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Differential Requirement of P2X7 Receptor and Intracellular K+ for Caspase-1 Activation Induced by Intracellular and Extracellular Bacteria

The Journal of biological chemistry, 2007-06, Vol.282 (26), p.18810-18818

2007

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Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

Immunity (Cambridge, Mass.), 2007-04, Vol.26 (4), p.433-443

2007

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S1423 RIPK2 Scaffolding Inhibitors are a Novel Approach to Block RIPK2 Signaling, a Hallmark of Inflammatory Bowel Disease

The American journal of gastroenterology, 2024-10, Vol.119 (10S), p.S1020-S1020

2024

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The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands

Immunity (Cambridge, Mass.), 2008-02, Vol.28 (2), p.246-257

2008

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Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

PLoS pathogens, 2007-08, Vol.3 (8), p.e111-e111

2007

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Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA

The Journal of biological chemistry, 2006-12, Vol.281 (48), p.36560-36568

2006

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Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf

The Journal of biological chemistry, 2006-11, Vol.281 (46), p.35217-35223

2006

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Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation

European journal of immunology, 2007-11, Vol.37 (11), p.3030-3039

2007

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Nature, 2006-03, Vol.440 (7081), p.233-236

2006

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Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis

The Journal of immunology (1950), 2017-04, Vol.198 (7), p.2735-2746

2017

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Caspase-1 inflammasomes in infection and inflammation

Journal of leukocyte biology, 2007-08, Vol.82 (2), p.220-225

2007

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P2X7 Receptor-Stimulated Secretion of MHC Class II-Containing Exosomes Requires the ASC/NLRP3 Inflammasome but Is Independent of Caspase-1

The Journal of immunology (1950), 2009-04, Vol.182 (8), p.5052-5062

2009

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Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

Nature communications, 2024-10, Vol.15 (1), p.8983-21, Article 8983

2024

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Inflammasomes as microbial sensors

European journal of immunology, 2010-03, Vol.40 (3), p.611-615

2010

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Sensing and reacting to microbes through the inflammasomes

Role of inflammasomes in intestinal inflammation and Crohn's disease

Function of Nod-like receptors in microbial recognition and host defense

The protein kinase PKR is critical for LPS‐induced iNOS production but dispensable for inflammasome activation in macrophages

A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome

Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux

The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria

RNase L Activates the NLRP3 Inflammasome during Viral Infections

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ

Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

Differential Requirement of P2X7 Receptor and Intracellular K+ for Caspase-1 Activation Induced by Intracellular and Extracellular Bacteria

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

S1423 RIPK2 Scaffolding Inhibitors are a Novel Approach to Block RIPK2 Signaling, a Hallmark of Inflammatory Bowel Disease

The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA

Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf

Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis

Caspase-1 inflammasomes in infection and inflammation

P2X7 Receptor-Stimulated Secretion of MHC Class II-Containing Exosomes Requires the ASC/NLRP3 Inflammasome but Is Independent of Caspase-1

Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

Inflammasomes as microbial sensors

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