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Systematic review and meta-analysis of in vitro efficacy of antibiotic combination therapy against carbapenem-resistant Gram-negative bacilli

International journal of antimicrobial agents, 2021-05, Vol.57 (5), p.106344-106344, Article 106344

2021

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Potential Antibiotics for the Treatment of Neonatal Sepsis Caused by Multidrug-Resistant Bacteria

Paediatric drugs, 2021-09, Vol.23 (5), p.465-484

2021

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High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium

Cell, 2001-11, Vol.107 (5), p.679-688

2001

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Pharmacokinetic/pharmacodynamic considerations for new and current therapeutic drugs for uncomplicated gonorrhoea—challenges and opportunities

Clinical microbiology and infection, 2020-12, Vol.26 (12), p.1630-1635

2020

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Rχ-01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance

Antimicrobial Agents and Chemotherapy, 2008-10, Vol.52 (10), p.3550-3557

2008

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Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance

Antimicrobial agents and chemotherapy, 2021-06, Vol.65 (7), p.e0029321-e0029321

2021

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Flomoxef and fosfomycin in combination for the treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance

Journal of antimicrobial chemotherapy, 2022-04, Vol.77 (5), p.1334-1343

2022

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Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings

Journal of antimicrobial chemotherapy, 2022-11, Vol.77 (12), p.3349-3357

2022

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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

Nature (London), 2001-10, Vol.413 (6858), p.814-821

2001

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Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution

Cell, 2000-09, Vol.102 (5), p.615-623

2000

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Structure-based drug design meets the ribosome

Biochemical pharmacology, 2006-03, Vol.71 (7), p.1016-1025

2006

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Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3

The EMBO journal, 2001-04, Vol.20 (8), p.1829-1839

2001

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30 Determining a potential alternative empirical antibiotic regimen for the treatment of neonatal sepsis in low- and middle-income settings using pre-clinical in vitro techniques

Clinical infection in practice, 2022-09, Vol.15, p.100191, Article 100191

2022

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Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit

Journal of medicinal chemistry, 2008-06, Vol.51 (12), p.3353-3356

2008

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Genomic surveillance and antimicrobial resistance in Neisseria gonorrhoeae isolates in Bangkok, Thailand in 2018

Journal of antimicrobial chemotherapy, 2022-07, Vol.77 (8), p.2171-2182

2022

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Pharmacodynamic Evaluation of Zoliflodacin Treatment of Neisseria gonorrhoeae Strains With Amino Acid Substitutions in the Zoliflodacin Target GyrB Using a Dynamic Hollow Fiber Infection Model

Frontiers in pharmacology, 2022-04, Vol.13, p.874176-874176

2022

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The role of combination therapy in the treatment of severe infections caused by carbapenem resistant gram-negatives: a systematic review of clinical studies

BMC infectious diseases, 2021-06, Vol.21 (1), p.1-545, Article 545

2021

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Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model

Frontiers in pharmacology, 2021-05, Vol.12, p.682135

2021

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Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

Frontiers in pharmacology, 2022-11, Vol.13, p.1035841-1035841

2022

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Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model

Frontiers in pharmacology, 2023, Vol.14, p.1291885-1291885

2023

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In Vitro Activities of the Rx-01 Oxazolidinones against Hospital and Community Pathogens

Antimicrobial Agents and Chemotherapy, 2008-05, Vol.52 (5), p.1653-1662

2008

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Structural Basis for the Antibiotic Activity of Ketolides and Azalides

Structure (London), 2003-03, Vol.11 (3), p.329-338

2003

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Structural Basis of the Ribosomal Machinery for Peptide Bond Formation, Translocation, and Nascent Chain Progression

Molecular cell, 2003, Vol.11 (1), p.91-102

2003

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Back to the future: the ribosome as an antibiotic target

Future microbiology, 2007-12, Vol.2 (6), p.571-574

Franceschi, Franççois

2007

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The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: Pattern fittings and the identification of a functional site

Proceedings of the National Academy of Sciences - PNAS, 1999-12, Vol.96 (25), p.14252-14257

1999

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Systematic review and meta-analysis of in vitro efficacy of antibiotic combination therapy against carbapenem-resistant Gram-negative bacilli

Potential Antibiotics for the Treatment of Neonatal Sepsis Caused by Multidrug-Resistant Bacteria

High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium

Pharmacokinetic/pharmacodynamic considerations for new and current therapeutic drugs for uncomplicated gonorrhoea—challenges and opportunities

Rχ-01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance

Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance

Flomoxef and fosfomycin in combination for the treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance

Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution

Structure-based drug design meets the ribosome

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3

30 Determining a potential alternative empirical antibiotic regimen for the treatment of neonatal sepsis in low- and middle-income settings using pre-clinical in vitro techniques

Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit

Genomic surveillance and antimicrobial resistance in Neisseria gonorrhoeae isolates in Bangkok, Thailand in 2018

Pharmacodynamic Evaluation of Zoliflodacin Treatment of Neisseria gonorrhoeae Strains With Amino Acid Substitutions in the Zoliflodacin Target GyrB Using a Dynamic Hollow Fiber Infection Model

The role of combination therapy in the treatment of severe infections caused by carbapenem resistant gram-negatives: a systematic review of clinical studies

Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model

Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model

In Vitro Activities of the Rx-01 Oxazolidinones against Hospital and Community Pathogens

Structural Basis for the Antibiotic Activity of Ketolides and Azalides

Structural Basis of the Ribosomal Machinery for Peptide Bond Formation, Translocation, and Nascent Chain Progression

Back to the future: the ribosome as an antibiotic target

The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: Pattern fittings and the identification of a functional site

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