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The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome

International Journal of Nanomedicine, 2016-01, Vol.11, p.6297-6306

2016

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Impacto funcional de polimorfismos del gen de la esclerostina sobre la metilación de ADN y la expresión génica

Revista de osteoporosis y metabolismo mineral, 2019-12, Vol.11 (4), p.98-104

2019

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Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Aging cell, 2022-03, Vol.21 (3), p.e13578-n/a

2022

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Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)

The Journal of pathology, 2006-12, Vol.210 (4), p.441-449

2006

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Epigenetic Differences Arise during the Lifetime of Monozygotic Twins

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (30), p.10604-10609

2005

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DNA methyltransferases control telomere length and telomere recombination in mammalian cells

Nature cell biology, 2006-04, Vol.8 (4), p.416-424

2006

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The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

Journal of cell science, 2003-02, Vol.116 (Pt 3), p.499-511

2003

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Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells

Cancer research (Chicago, Ill.), 2003-08, Vol.63 (16), p.4984-4989

2003

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Nature genetics, 2005-04, Vol.37 (4), p.391-400

2005

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Towards the Human Cancer Epigenome: A First Draft of Histone Modifications

Cell cycle (Georgetown, Tex.), 2005-10, Vol.4 (10), p.1377-1381

2005

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DNA Methylation Polymorphisms Precede Any Histological Sign of Atherosclerosis in Mice Lacking Apolipoprotein E

The Journal of biological chemistry, 2004-07, Vol.279 (28), p.29147-29154

2004

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A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

Nature genetics, 2006-05, Vol.38 (5), p.566-569

2006

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Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

Nature cell biology, 2005-04, Vol.7 (4), p.420-428

2005

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Methyl‐CpG binding proteins identify novel sites of epigenetic inactivation in human cancer

The EMBO journal, 2003-12, Vol.22 (23), p.6335-6345

2003

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A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

Cancer research (Chicago, Ill.), 2004-08, Vol.64 (16), p.5527-5534

2004

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The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

Nucleic acids research, 2003-03, Vol.31 (6), p.1765

2003

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Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors

Cancer research (Chicago, Ill.), 2002-08, Vol.62 (15), p.4519-4524

2002

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EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma

Cancer research (Chicago, Ill.), 2005-04, Vol.65 (7), p.2565-2571

2005

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The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding

Carcinogenesis (New York), 2006-05, Vol.27 (5), p.1099-1104

2006

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DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis

Human molecular genetics, 2001-12, Vol.10 (26), p.3001-3007

2001

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Inactivation of the Lamin A/C Gene by CpG Island Promoter Hypermethylation in Hematologic Malignancies, and Its Association With Poor Survival in Nodal Diffuse Large B-Cell Lymphoma

Journal of clinical oncology, 2005-06, Vol.23 (17), p.3940-3947

2005

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Epigenomics in Health and Disease

Mario Fraga, Agustin Fernandez Fernandez / Mario Fraga, Agustin Fernandez Fernandez

1, 2015

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Genomic DNA methylation-demethylation during aging and reinvigoration of Pinus radiata

Tree physiology, 2002-08, Vol.22 (11), p.813-816

2002

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CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer

Oncogene, 2004-11, Vol.23 (53), p.8695-8699

2004

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Angiostatic activity of DNA methyltransferase inhibitors

Molecular cancer therapeutics, 2006-02, Vol.5 (2), p.467-475

2006

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The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome

Impacto funcional de polimorfismos del gen de la esclerostina sobre la metilación de ADN y la expresión génica

Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)

Epigenetic Differences Arise during the Lifetime of Monozygotic Twins

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Towards the Human Cancer Epigenome: A First Draft of Histone Modifications

DNA Methylation Polymorphisms Precede Any Histological Sign of Atherosclerosis in Mice Lacking Apolipoprotein E

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

Methyl‐CpG binding proteins identify novel sites of epigenetic inactivation in human cancer

A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors

EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma

The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding

DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis

Inactivation of the Lamin A/C Gene by CpG Island Promoter Hypermethylation in Hematologic Malignancies, and Its Association With Poor Survival in Nodal Diffuse Large B-Cell Lymphoma

Epigenomics in Health and Disease

Genomic DNA methylation-demethylation during aging and reinvigoration of Pinus radiata

CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer

Angiostatic activity of DNA methyltransferase inhibitors

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