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IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling

The Journal of immunology (1950), 2015-11, Vol.195 (9), p.4144-4153

2015

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Comparing the biological impact of glatiramer acetate with the biological impact of a generic

PloS one, 2014-01, Vol.9 (1), p.e83757

2014

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HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

Nature immunology, 2011-01, Vol.12 (1), p.54-61

2011

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A model for how signal duration can determine distinct outcomes of gene transcription programs

PloS one, 2012-03, Vol.7 (3), p.e33018-e33018

2012

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Empty Class II Major Histocompatibility Complex Created by Peptide Photolysis Establishes the Role of DM in Peptide Association

The Journal of biological chemistry, 2007-07, Vol.282 (29), p.21425-21436

2007

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Pridopidine activates neuroprotective pathways impaired in Huntington Disease

Human molecular genetics, 2016-09, Vol.25 (18), p.3975-3987

2016

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Leveraging existing data sets to generate new insights into Alzheimer’s disease biology in specific patient subsets

Scientific reports, 2015-09, Vol.5 (1), p.14324-14324, Article 14324

2015

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Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition

Journal of neuroimmunology, 2016-01, Vol.290, p.84-95

2016

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Compositional differences between Copaxone and Glatopa are reflected in altered immunomodulation ex vivo in a mouse model

Annals of the New York Academy of Sciences, 2017-11, Vol.1407 (1), p.75-89

2017

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Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids

Scientific reports, 2015-05, Vol.5 (1), p.10191-10191, Article 10191

2015

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Abstract P254: Transcriptional effects in C26 tumor highlight mechanistic aspects of a novel dual MEK inhibitor, IMM-1-104

Molecular cancer therapeutics, 2021-12, Vol.20 (12_Supplement), p.P254-P254

2021

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Abstract P240: Benchmarking the novel dual-MEK inhibitor, IMM-1-104, head-to-head and in combination with sotorasib (AMG-510) in the MIA PaCa-2 (KRAS-G12C) pancreatic cancer xenograft model

Molecular cancer therapeutics, 2021-12, Vol.20 (12_Supplement), p.P240-P240

2021

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Abstract P252: IMM-1-104: a novel, oral, selective dual-MEK inhibitor that displays broad antitumor activity and high tolerability across RAS and RAF mutant tumors in vivo

Molecular cancer therapeutics, 2021-12, Vol.20 (12_Supplement), p.P252-P252

2021

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Abstract 1509: Cachexia: Leveraging transcriptomics to identify potential therapeutics

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1509-1509

2018

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Abstract 5177: Metastasis: Leveraging transcriptomics to identify potential therapeutics

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5177-5177

2018

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IL-27 induces Th17 differentiation in the absence of STAT1 signaling1

The Journal of immunology (1950), 2015-09, Vol.195 (9), p.4144-4153

2015

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Abstract B027: A meta-metastasis analysis identifies pan-cancer markers and therapeutic targets

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.B027-B027

2018

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Abstract 4265: Humanized 3D tumor models that are mutationally aligned with AACR GENIE patients predict IMM-1-104 activity in RAS-addicted tumors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.4265-4265

2023

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Abstract A134: Predicting activity of IMM-1-104 as single agent and in combination for patients with RAS or RAF mutant tumors

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.A134-A134

2023

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Abstract A093: Deep Cyclic Inhibition of the MAPK pathway with IMM-6-415, alone and in combination with encorafenib, demonstrates anti-tumor activity and tolerability in RAF mutant tumors in vivo

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.A093-A093

2023

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Abstract B021: Pan-RAS IMM-1-104 activity in humanized 3D tumor models is independent of specific amino acid substitution

Molecular cancer research, 2023-05, Vol.21 (5_Supplement), p.B021-B021

2023

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Signal Specificity Amongst STAT1- and STAT3- Inducing Cytokines in the Context of Th17 Differentiation

Fowler, Kevin D

2012

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Comparing the Biological Impact of Glatiramer Acetate with the Biological Impact of a Generic: e83757

PloS one, 2014-01, Vol.9 (1)

2014

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Empty Class II Major Histocompatibility Complex Created by Peptide Photolysis Establishes the Role of DM in Peptide AssociationS

The Journal of biological chemistry, 2007-05, Vol.282 (29), p.21425-21436

2007

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Long-term effects of the Diabetes Prevention Program interventions on cardiovascular risk factors: a report from the DPP Outcomes Study

Diabetic medicine, 2013-01, Vol.30 (1), p.46-55

2013

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IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling

Comparing the biological impact of glatiramer acetate with the biological impact of a generic

HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

A model for how signal duration can determine distinct outcomes of gene transcription programs

Empty Class II Major Histocompatibility Complex Created by Peptide Photolysis Establishes the Role of DM in Peptide Association

Pridopidine activates neuroprotective pathways impaired in Huntington Disease

Leveraging existing data sets to generate new insights into Alzheimer’s disease biology in specific patient subsets

Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition

Compositional differences between Copaxone and Glatopa are reflected in altered immunomodulation ex vivo in a mouse model

Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids

Abstract P254: Transcriptional effects in C26 tumor highlight mechanistic aspects of a novel dual MEK inhibitor, IMM-1-104

Abstract P240: Benchmarking the novel dual-MEK inhibitor, IMM-1-104, head-to-head and in combination with sotorasib (AMG-510) in the MIA PaCa-2 (KRAS-G12C) pancreatic cancer xenograft model

Abstract P252: IMM-1-104: a novel, oral, selective dual-MEK inhibitor that displays broad antitumor activity and high tolerability across RAS and RAF mutant tumors in vivo

Abstract 1509: Cachexia: Leveraging transcriptomics to identify potential therapeutics

Abstract 5177: Metastasis: Leveraging transcriptomics to identify potential therapeutics

IL-27 induces Th17 differentiation in the absence of STAT1 signaling1

Abstract B027: A meta-metastasis analysis identifies pan-cancer markers and therapeutic targets

Abstract 4265: Humanized 3D tumor models that are mutationally aligned with AACR GENIE patients predict IMM-1-104 activity in RAS-addicted tumors

Abstract A134: Predicting activity of IMM-1-104 as single agent and in combination for patients with RAS or RAF mutant tumors

Abstract A093: Deep Cyclic Inhibition of the MAPK pathway with IMM-6-415, alone and in combination with encorafenib, demonstrates anti-tumor activity and tolerability in RAF mutant tumors in vivo

Abstract B021: Pan-RAS IMM-1-104 activity in humanized 3D tumor models is independent of specific amino acid substitution

Signal Specificity Amongst STAT1- and STAT3- Inducing Cytokines in the Context of Th17 Differentiation

Comparing the Biological Impact of Glatiramer Acetate with the Biological Impact of a Generic: e83757

Empty Class II Major Histocompatibility Complex Created by Peptide Photolysis Establishes the Role of DM in Peptide AssociationS

Long-term effects of the Diabetes Prevention Program interventions on cardiovascular risk factors: a report from the DPP Outcomes Study

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