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Inhibition of Wee1 sensitizes cancer cells to antimetabolite chemotherapeutics in vitro and in vivo, independent of p53 functionality

Molecular cancer therapeutics, 2013-12, Vol.12 (12), p.2675-2684

2013

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STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious

Cancer research (Chicago, Ill.), 2014-05, Vol.74 (9), p.2579-2590

2014

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A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia

Molecular cancer therapeutics, 2017-10, Vol.16 (10), p.2058-2068

2017

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Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma

BMC cancer, 2010-11, Vol.10 (1), p.619-619, Article 619

2010

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Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine

Leukemia research, 2018-01, Vol.64, p.30-33

2018

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Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

Cell reports (Cambridge), 2020-10, Vol.33 (3), p.108286-108286, Article 108286

2020

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Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma

Cell reports (Cambridge), 2020-04, Vol.31 (1), p.107485-107485, Article 107485

2020

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A Regulatory Loop of FBXW7-MYC-PLK1 Controls Tumorigenesis of MYC-Driven Medulloblastoma

Cancers, 2021-01, Vol.13 (3), p.387

2021

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IL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (14), p.3702-3713

2019

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Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance

Molecular cancer, 2007-02, Vol.6 (1), p.16-16, Article 16

2007

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Knockdown of HPRT for selection of genetically modified human hematopoietic progenitor cells

PloS one, 2013-03, Vol.8 (3), p.e59594

2013

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Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium

Laboratory investigation, 2004-05, Vol.84 (5), p.562-572

2004

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Influence of genetic background on tumor karyotypes: Evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma

Chromosome research, 2009-04, Vol.17 (3), p.365-377

2009

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Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Genome research, 2005-12, Vol.15 (12), p.1831-1837

2005

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Nicotine-mediated signals modulate cell death and survival of T lymphocytes

Toxicology and applied pharmacology, 2010-02, Vol.242 (3), p.299-309

2010

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Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells

The Journal of pharmacology and experimental therapeutics, 2004-11, Vol.311 (2), p.758-769

2004

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DIPG-55. TARGETING SENESCENT CELLS WITH ABT-263 ENHANCES CELL DEATH INDUCED BY BMI1 INHIBITION AND IONIZING RADIATION IN DIPG

Neuro-oncology (Charlottesville, Va.), 2018-06, Vol.20 (suppl_2), p.i60-i60

2018

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A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy

Neuro-oncology (Charlottesville, Va.), 2022-03, Vol.24 (3), p.414-426

2022

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ATRT-20. CDK7 INHIBITION IN AT/RT

Neuro-oncology (Charlottesville, Va.), 2020-12, Vol.22 (Supplement_3), p.iii279-iii280

2020

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MBRS-65. FBXW7 ACTS A TUMOR SUPPRESSOR IN MYC-DRIVEN MEDULLOBLASTOMA BY CONTROLLING A FEED-FORWARD REGULATORY LOOP OF PLK1 AND MYC

Neuro-oncology (Charlottesville, Va.), 2020-12, Vol.22 (Supplement_3), p.iii409-iii409

2020

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DIPG-32. PRECLINICAL TESTING OF THE EFFICACY AND SAFETY OF CRISPR/CAS9 GENE EDITED CAR-T CELL THERAPY FOR DIFFUSE MIDLINE GLIOMA (DMG)

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i20-i20

2023

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MBRS-23. EFFECT OF KNOCKDOWN OF KDM6A BY CRISPR/CAS9 EDITING IN MEDULLOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2018-06, Vol.20 (suppl_2), p.i133-i133

2018

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Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma

Cell reports (Cambridge), 2021-04, Vol.35 (4), p.109013-109013, Article 109013

2021

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DIPG-56. Development and application of a novel antibody against CD99 as a therapeutic strategy in Diffuse Midline Glioma

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i31-i31

2022

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Inhibition of Wee1 sensitizes cancer cells to antimetabolite chemotherapeutics in vitro and in vivo, independent of p53 functionality

STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious

A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia

Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma

Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine

Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia

Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma

A Regulatory Loop of FBXW7-MYC-PLK1 Controls Tumorigenesis of MYC-Driven Medulloblastoma

IL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression

Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance

Knockdown of HPRT for selection of genetically modified human hematopoietic progenitor cells

Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium

Influence of genetic background on tumor karyotypes: Evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Nicotine-mediated signals modulate cell death and survival of T lymphocytes

Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells

DIPG-55. TARGETING SENESCENT CELLS WITH ABT-263 ENHANCES CELL DEATH INDUCED BY BMI1 INHIBITION AND IONIZING RADIATION IN DIPG

A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy

ATRT-20. CDK7 INHIBITION IN AT/RT

MBRS-65. FBXW7 ACTS A TUMOR SUPPRESSOR IN MYC-DRIVEN MEDULLOBLASTOMA BY CONTROLLING A FEED-FORWARD REGULATORY LOOP OF PLK1 AND MYC

DIPG-32. PRECLINICAL TESTING OF THE EFFICACY AND SAFETY OF CRISPR/CAS9 GENE EDITED CAR-T CELL THERAPY FOR DIFFUSE MIDLINE GLIOMA (DMG)

MBRS-23. EFFECT OF KNOCKDOWN OF KDM6A BY CRISPR/CAS9 EDITING IN MEDULLOBLASTOMA

Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma

DIPG-56. Development and application of a novel antibody against CD99 as a therapeutic strategy in Diffuse Midline Glioma

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