UB Paderborn / Katalog / Suche / in CDI

Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

Nature structural & molecular biology, 2010-09, Vol.17 (9), p.1152

2010

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Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin

Nature communications, 2015-12, Vol.6 (1), p.10048-10048, Article 10048

2015

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Type IIA topoisomerase inhibition by a new class of antibacterial agents

Nature (London), 2010-08, Vol.466 (7309), p.935-940

2010

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Structure-activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal

Scientific reports, 2023-11, Vol.13 (1), p.19052-19052, Article 19052

2023

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Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses

PloS one, 2012-07, Vol.7 (7), p.e39847

2012

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Crystallization and initial crystallographic analysis of covalent DNA-cleavage complexes of Staphyloccocus aureus DNA gyrase with QPT-1, moxifloxacin and etoposide

Acta crystallographica. Section F, Structural biology communications, 2015-10, Vol.71 (10), p.1242-1246

2015

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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2061-2065

2001

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The antimicrobial natural product chuangxinmycin and Some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase

Bioorganic & medicinal chemistry letters, 2002-11, Vol.12 (21), p.3171-3174

2002

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Nuclear magnetic resonance spectroscopy reveals the functional state of the signalling protein CheY in vivo in Escherichia coli

Molecular microbiology, 2003-09, Vol.49 (5), p.1191-1200

2003

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Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Antimicrobial Agents and Chemotherapy, 2002-10, Vol.46 (10), p.3118-3124

2002

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Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (17), p.2241-2244

2001

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Discovery and optimisation of potent, selective, ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2305-2309

2005

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Potential of real-time measurement of GFP-fusion proteins

Journal of biotechnology, 2004-04, Vol.109 (1), p.201-211

2004

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Impact of high throughput technology on recombinant protein production

Microbial cell factories, 2006-10, Vol.5 (Suppl 1), p.S30-S30

2006

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Development of an Enzymatic Process for the Production of (R)‑2-Butyl-2-ethyloxirane

Organic process research & development, 2017-09, Vol.21 (9), p.1302-1310

2017

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Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterization

Gene, 1995-12, Vol.166 (1), p.49-55

1995

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Inhibitors of the DNA-cleavage gate of bacterial type IIA topoisomerases

Acta crystallographica. Section A, Foundations and advances, 2014-08, Vol.70 (a1), p.C204-C204

2014

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Crystal structure of Staphylococcus aureus tyrosyl‐tRNA synthetase in complex with a class of potent and specific inhibitors

Protein science, 2001-10, Vol.10 (10), p.2008-2016

2001

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Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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Correction: Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

PloS one, 2012-09, Vol.7 (9)

2012

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Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NF[kappa]B Responses

PloS one, 2012-07, Vol.7 (7), p.e39847

2012

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Lead discovery for microsomal prostaglandin E synthase using a combination of high-throughput fluorescent-based assays and RapidFire mass spectrometry

Journal of biomolecular screening, 2012-06, Vol.17 (5), p.641-650

2012

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Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species

Protein science, 2003-02, Vol.12 (2), p.349-360

2003

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Cloning and pharmacological characterisation of the guinea pig 5-ht 5A receptor

European journal of pharmacology, 2004-06, Vol.494 (2), p.91-99

2004

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Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin

Type IIA topoisomerase inhibition by a new class of antibacterial agents

Structure-activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal

Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses

Crystallization and initial crystallographic analysis of covalent DNA-cleavage complexes of Staphyloccocus aureus DNA gyrase with QPT-1, moxifloxacin and etoposide

1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

The antimicrobial natural product chuangxinmycin and Some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase

Nuclear magnetic resonance spectroscopy reveals the functional state of the signalling protein CheY in vivo in Escherichia coli

Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Discovery and optimisation of potent, selective, ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase

Potential of real-time measurement of GFP-fusion proteins

Impact of high throughput technology on recombinant protein production

Development of an Enzymatic Process for the Production of (R)‑2-Butyl-2-ethyloxirane

Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterization

Inhibitors of the DNA-cleavage gate of bacterial type IIA topoisomerases

Crystal structure of Staphylococcus aureus tyrosyl‐tRNA synthetase in complex with a class of potent and specific inhibitors

Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Correction: Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NF[kappa]B Responses

Lead discovery for microsomal prostaglandin E synthase using a combination of high-throughput fluorescent-based assays and RapidFire mass spectrometry

Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species

Cloning and pharmacological characterisation of the guinea pig 5-ht 5A receptor

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