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Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication

PLoS pathogens, 2017-09, Vol.13 (9), p.e1006635

2017

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DEAD-box ATPases are global regulators of phase-separated organelles

Nature (London), 2019-09, Vol.573 (7772), p.144-148

2019

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PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (10), p.3956-3961

2012

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Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex

Nature communications, 2023-04, Vol.14 (1), p.2304-2304, Article 2304

2023

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Chemical intervention of influenza virus mRNA nuclear export

PLoS pathogens, 2020-04, Vol.16 (4), p.e1008407

2020

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SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (45), p.28344-28354

2020

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Influenza virus targets the mRNA export machinery and the nuclear pore complex

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (6), p.1853-1858

2007

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Günter Blobel 1936–2018

Nature structural & molecular biology, 2018-04, Vol.25 (4), p.297-298

2018

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Nucleoporin Levels Regulate Cell Cycle Progression and Phase-Specific Gene Expression

Developmental cell, 2008-11, Vol.15 (5), p.657-667

2008

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Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

Neuron (Cambridge, Mass.), 2019-05, Vol.102 (3), p.587-601.e7

2019

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UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

PLoS pathogens, 2016-01, Vol.12 (1), p.e1005370

2016

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Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing

Nature communications, 2018-06, Vol.9 (1), p.2407-12, Article 2407

2018

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Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1

Molecular biology of the cell, 2011-12, Vol.22 (23), p.4657-4668

2011

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Nuclear Trafficking in Health and Disease

Current opinion in cell biology, 2014-06, Vol.28, p.28-35

2014

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Viral Subversion of Nucleocytoplasmic Trafficking

Traffic (Copenhagen, Denmark), 2014-02, Vol.15 (2), p.127-140

2014

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Role of Nucleoporin Induction in Releasing an mRNA Nuclear Export Block

Science (American Association for the Advancement of Science), 2002-02, Vol.295 (5559), p.1523-1525

2002

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Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.10951-10966

2021

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Structural–functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (52), p.E12218-E12227

2018

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NFAR-1 and -2 modulate translation and are required for efficient host defense

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (11), p.4173-4178

2008

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Primate-specific miR-576-3p sets host defense signalling threshold

Nature communications, 2014-09, Vol.5 (1), p.4963-4963, Article 4963

2014

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Structural basis for influenza virus NS1 protein block of mRNA nuclear export

Nature microbiology, 2019-10, Vol.4 (10), p.1671-1679

2019

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Structure-based design of a pathway-specific nuclear import inhibitor

Nature structural & molecular biology, 2007-05, Vol.14 (5), p.452-454

2007

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Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export

Viruses, 2013-07, Vol.5 (7), p.1824-1849

2013

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Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

Nature chemical biology, 2011-09, Vol.7 (10), p.712-719

2011

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Discrete spatio-temporal regulation of tyrosine phosphorylation directs influenza A virus M1 protein towards its function in virion assembly

PLoS pathogens, 2020-08, Vol.16 (8), p.e1008775-e1008775

2020

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Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication

DEAD-box ATPases are global regulators of phase-separated organelles

PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium

Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex

Chemical intervention of influenza virus mRNA nuclear export

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

Influenza virus targets the mRNA export machinery and the nuclear pore complex

Günter Blobel 1936–2018

Nucleoporin Levels Regulate Cell Cycle Progression and Phase-Specific Gene Expression

Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing

Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1

Nuclear Trafficking in Health and Disease

Viral Subversion of Nucleocytoplasmic Trafficking

Role of Nucleoporin Induction in Releasing an mRNA Nuclear Export Block

Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein

Structural–functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression

NFAR-1 and -2 modulate translation and are required for efficient host defense

Primate-specific miR-576-3p sets host defense signalling threshold

Structural basis for influenza virus NS1 protein block of mRNA nuclear export

Structure-based design of a pathway-specific nuclear import inhibitor

Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

Discrete spatio-temporal regulation of tyrosine phosphorylation directs influenza A virus M1 protein towards its function in virion assembly

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