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Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years: A Randomized Clinical Trial

JAMA ophthalmology, 2023-10, Vol.141 (10), p.990

2023

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The melanocortin system

American journal of physiology: endocrinology and metabolism, 2003-03, Vol.284 (3), p.E468-E474

2003

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Neuronal activation in the hypothalamus and brainstem during feeding in rats

Cell metabolism, 2006-10, Vol.4 (4), p.313-321

2006

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[¹⁸F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (23), p.9800-9805

2007

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Body circumferences: clinical implications emerging from a new geometric model

Nutrition & metabolism, 2008-10, Vol.5 (1), p.24-24, Article 24

2008

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Molecular Determinants of Ligand Binding to the Human Melanocortin-4 Receptor

Biochemistry (Easton), 2000-12, Vol.39 (48), p.14900-14911

2000

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Constitutive Activity in Cannabinoid Receptors

Advances in Pharmacology, 2014, Vol.70, p.121-133

Fong, Tung M.

2014

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Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2330-2334

2011

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Galanin and Galanin-Like Peptide Differentially Modulate Neuronal Activities in Rat Arcuate Nucleus Neurons

Journal of neurophysiology, 2006-05, Vol.95 (5), p.3228-3234

2006

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The role of melanocortins in body weight regulation: opportunities for the treatment of obesity

European journal of pharmacology, 2002-08, Vol.450 (1), p.93-109

2002

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Molecular Basis of the Pharmacological Difference between Rat and Human Bombesin Receptor Subtype-3 (BRS-3)

Biochemistry (Easton), 2002-07, Vol.41 (28), p.8954-8960

2002

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Measurement of Inverse Agonism of the Cannabinoid Receptors

Methods in Enzymology, 2010, Vol.485, p.139-145

Fong, Tung M.

2010

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Melanocortin-4 Receptor (MC4R) Agonists for the Treatment of Obesity

Journal of medicinal chemistry, 2006-07, Vol.49 (14), p.4035-4043

2006

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Synthesis and evaluation of N-[(1 S,2 S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (17), p.5195-5199

2009

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The role of melanocortins in body weight regulation: opportunities for the treatment of obesity

European journal of pharmacology, 2002-04, Vol.440 (2), p.141-157

2002

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Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity

Journal of medicinal chemistry, 2006-12, Vol.49 (26), p.7584-7587

2006

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Genome-wide expression profiling revealed peripheral effects of cannabinoid receptor 1 inverse agonists in improving insulin sensitivity and metabolic parameters

Molecular pharmacology, 2010-09, Vol.78 (3), p.350-359

2010

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Reduced sensitivity to diet-induced obesity in mice carrying a mutant 5-HT6 receptor

Brain research, 2008-10, Vol.1236, p.140-144

2008

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Antiobesity Efficacy of a Novel Cannabinoid-1 Receptor Inverse Agonist, N -[(1 S ,2 S )-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), in Rodents

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.1013-1022

2007

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Development of anti-obesity agents: drugs that target neuropeptide and neurotransmitter systems

Expert opinion on investigational drugs, 2008-03, Vol.17 (3), p.321-325

Fong, Tung M

2008

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Interactions of Human Melanocortin 4 Receptor with Nonpeptide and Peptide Agonists

Biochemistry (Easton), 2005-08, Vol.44 (34), p.11329-11341

2005

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Conformational Analysis and Receptor Docking of N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (Taranabant, MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist

Journal of medicinal chemistry, 2008-04, Vol.51 (7), p.2108-2114

2008

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Pharmacological evaluation of LH-21, a newly discovered molecule that binds to cannabinoid CB1 receptor

European journal of pharmacology, 2008-04, Vol.584 (2-3), p.338-342

2008

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Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years: A Randomized Clinical Trial

The melanocortin system

Neuronal activation in the hypothalamus and brainstem during feeding in rats

[¹⁸F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor

The Acyclic CB1R Inverse Agonist Taranabant Mediates Weight Loss by Increasing Energy Expenditure and Decreasing Caloric Intake

Body circumferences: clinical implications emerging from a new geometric model

Molecular Determinants of Ligand Binding to the Human Melanocortin-4 Receptor

Constitutive Activity in Cannabinoid Receptors

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist

Galanin and Galanin-Like Peptide Differentially Modulate Neuronal Activities in Rat Arcuate Nucleus Neurons

The role of melanocortins in body weight regulation: opportunities for the treatment of obesity

Molecular Basis of the Pharmacological Difference between Rat and Human Bombesin Receptor Subtype-3 (BRS-3)

Measurement of Inverse Agonism of the Cannabinoid Receptors

Melanocortin-4 Receptor (MC4R) Agonists for the Treatment of Obesity

Synthesis and evaluation of N-[(1 S,2 S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists

The role of melanocortins in body weight regulation: opportunities for the treatment of obesity

Regulation of Energy Homeostasis by Bombesin Receptor Subtype-3: Selective Receptor Agonists for the Treatment of Obesity

Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity

Genome-wide expression profiling revealed peripheral effects of cannabinoid receptor 1 inverse agonists in improving insulin sensitivity and metabolic parameters

Reduced sensitivity to diet-induced obesity in mice carrying a mutant 5-HT6 receptor

Antiobesity Efficacy of a Novel Cannabinoid-1 Receptor Inverse Agonist, N -[(1 S ,2 S )-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), in Rodents

Development of anti-obesity agents: drugs that target neuropeptide and neurotransmitter systems

Interactions of Human Melanocortin 4 Receptor with Nonpeptide and Peptide Agonists

Conformational Analysis and Receptor Docking of N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (Taranabant, MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist

Pharmacological evaluation of LH-21, a newly discovered molecule that binds to cannabinoid CB1 receptor

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