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Cannabinoid-1 receptor inverse agonists: current understanding of mechanism of action and unanswered questions

International Journal of Obesity, 2009-09, Vol.33 (9), p.947-955

2009

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Molecular Determinants of Ligand Binding to the Human Melanocortin-4 Receptor

Biochemistry (Easton), 2000-12, Vol.39 (48), p.14900-14911

2000

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Molecular Interaction of Agouti Protein and Agouti-Related Protein with Human Melanocortin Receptors

Biochemistry (Easton), 1999-01, Vol.38 (3), p.897-904

1999

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Plasma Agouti-Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats

Journal of neuroendocrinology, 2002-08, Vol.14 (8), p.607-610

2002

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The role of histidine 265 in antagonist binding to the neurokinin-1 receptor

The Journal of biological chemistry, 1994-01, Vol.269 (4), p.2728-2732

1994

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Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors

Molecular pharmacology, 1992-06, Vol.41 (6), p.1096-1099

1992

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The family of G‐protein‐coupled receptors

The FASEB journal, 1995-06, Vol.9 (9), p.745-754

1995

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Synergistic effects of cannabinoid inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice

Brain research, 2004-03, Vol.999 (2), p.227-230

2004

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ART (Protein Product of Agouti-Related Transcript) as an Antagonist of MC-3 and MC-4 Receptors

Biochemical and biophysical research communications, 1997-08, Vol.237 (3), p.629-631

1997

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Identification of a Series of 3-(Benzyloxy)-1-azabicyclo[2.2.2]octane Human NK1 Antagonists

Journal of medicinal chemistry, 1995-11, Vol.38 (24), p.4793-4805

1995

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Functional mapping of the ligand binding sites of G-Protein coupled receptors

Medicinal research reviews, 1994-07, Vol.14 (4), p.387-399

1994

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Molecular basis for the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580

The Journal of biological chemistry, 1992-12, Vol.267 (36), p.25668-25671

1992

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Localization of agonist and antagonist binding domains of the human neurokinin-1 receptor

The Journal of biological chemistry, 1992-12, Vol.267 (36), p.25664-25667

1992

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Localization of the ligand binding site of the neurokinin-1 receptor: interpretation of chimeric mutations and single-residue substitutions

Molecular pharmacology, 1994-04, Vol.45 (4), p.690-695

1994

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Localization of Leptin Binding Domain in the Leptin Receptor

Molecular pharmacology, 1998-02, Vol.53 (2), p.234-240

1998

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The Concise Guide to PHARMACOLOGY 2015/16: Overview

British journal of pharmacology, 2015-12, Vol.172 (24), p.5729-5743

2015

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Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor

Molecular pharmacology, 1992-01, Vol.41 (1), p.24-30

1992

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Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells

Endocrinology (Philadelphia), 1996-11, Vol.137 (11), p.5178-5181

1996

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Characterization of the binding of [ 125I-iodo-histidyl,methyl-Phe 7] neurokinin B to the neurokinin-3 receptor

Neuropeptides (Edinburgh), 1993-06, Vol.24 (6), p.317-319

1993

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Thapsigargin blocks the mobilisation of intracellular calcium caused by activation of human NK1 (long) receptors expressed in chinese hamster ovary cells

Neuroscience letters, 1993-04, Vol.152 (1), p.9-12

1993

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Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor

Molecular pharmacology, 1992-09, Vol.42 (3), p.458-463

1992

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Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345

Nature (London), 1993-03, Vol.362 (6418), p.350-353

1993

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Relative contribution of polar interactions and conformational compatibility to the binding of neurokinin-1 receptor antagonists

Molecular pharmacology, 1996-12, Vol.50 (6), p.1605

1996

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Mutational analysis of neurokinin receptor function

Canadian journal of physiology and pharmacology, 1995-07, Vol.73 (7), p.860-865

1995

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Use of Bioluminescent Aequorin for the Pharmacological Characterization of 5ht Receptors

Journal of receptors and signal transduction, 1999-11, Vol.19 (6), p.927-938

1999

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Cannabinoid-1 receptor inverse agonists: current understanding of mechanism of action and unanswered questions

Molecular Determinants of Ligand Binding to the Human Melanocortin-4 Receptor

Molecular Interaction of Agouti Protein and Agouti-Related Protein with Human Melanocortin Receptors

Plasma Agouti-Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats

The role of histidine 265 in antagonist binding to the neurokinin-1 receptor

Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors

The family of G‐protein‐coupled receptors

Synergistic effects of cannabinoid inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice

ART (Protein Product of Agouti-Related Transcript) as an Antagonist of MC-3 and MC-4 Receptors

Identification of a Series of 3-(Benzyloxy)-1-azabicyclo[2.2.2]octane Human NK1 Antagonists

Functional mapping of the ligand binding sites of G-Protein coupled receptors

Molecular basis for the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580

Localization of agonist and antagonist binding domains of the human neurokinin-1 receptor

Localization of the ligand binding site of the neurokinin-1 receptor: interpretation of chimeric mutations and single-residue substitutions

Localization of Leptin Binding Domain in the Leptin Receptor

The Concise Guide to PHARMACOLOGY 2015/16: Overview

Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor

Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells

Characterization of the binding of [ 125I-iodo-histidyl,methyl-Phe 7] neurokinin B to the neurokinin-3 receptor

Thapsigargin blocks the mobilisation of intracellular calcium caused by activation of human NK1 (long) receptors expressed in chinese hamster ovary cells

Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor

Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345

Relative contribution of polar interactions and conformational compatibility to the binding of neurokinin-1 receptor antagonists

Mutational analysis of neurokinin receptor function

Use of Bioluminescent Aequorin for the Pharmacological Characterization of 5ht Receptors

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