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Cannabinoid-1 receptor inverse agonists: current understanding of mechanism of action and unanswered questions

International Journal of Obesity, 2009-09, Vol.33 (9), p.947-955

2009

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Molecular Determinants of Ligand Binding to the Human Melanocortin-4 Receptor

Biochemistry (Easton), 2000-12, Vol.39 (48), p.14900-14911

2000

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Molecular Interaction of Agouti Protein and Agouti-Related Protein with Human Melanocortin Receptors

Biochemistry (Easton), 1999-01, Vol.38 (3), p.897-904

1999

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Plasma Agouti-Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats

Journal of neuroendocrinology, 2002-08, Vol.14 (8), p.607-610

2002

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The role of histidine 265 in antagonist binding to the neurokinin-1 receptor

The Journal of biological chemistry, 1994-01, Vol.269 (4), p.2728-2732

1994

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Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors

Molecular pharmacology, 1992-06, Vol.41 (6), p.1096-1099

1992

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The family of G‐protein‐coupled receptors

The FASEB journal, 1995-06, Vol.9 (9), p.745-754

1995

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Synergistic effects of cannabinoid inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice

Brain research, 2004-03, Vol.999 (2), p.227-230

2004

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ART (Protein Product of Agouti-Related Transcript) as an Antagonist of MC-3 and MC-4 Receptors

Biochemical and biophysical research communications, 1997-08, Vol.237 (3), p.629-631

1997

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Identification of a Series of 3-(Benzyloxy)-1-azabicyclo[2.2.2]octane Human NK1 Antagonists

Journal of medicinal chemistry, 1995-11, Vol.38 (24), p.4793-4805

1995

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Functional mapping of the ligand binding sites of G-Protein coupled receptors

Medicinal research reviews, 1994-07, Vol.14 (4), p.387-399

1994

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Molecular basis for the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580

The Journal of biological chemistry, 1992-12, Vol.267 (36), p.25668-25671

1992

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Localization of agonist and antagonist binding domains of the human neurokinin-1 receptor

The Journal of biological chemistry, 1992-12, Vol.267 (36), p.25664-25667

1992

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Localization of the ligand binding site of the neurokinin-1 receptor: interpretation of chimeric mutations and single-residue substitutions

Molecular pharmacology, 1994-04, Vol.45 (4), p.690-695

1994

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Localization of Leptin Binding Domain in the Leptin Receptor

Molecular pharmacology, 1998-02, Vol.53 (2), p.234-240

1998

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Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor

Molecular pharmacology, 1992-01, Vol.41 (1), p.24-30

1992

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Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells

Endocrinology (Philadelphia), 1996-11, Vol.137 (11), p.5178-5181

1996

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Characterization of the binding of [ 125I-iodo-histidyl,methyl-Phe 7] neurokinin B to the neurokinin-3 receptor

Neuropeptides (Edinburgh), 1993-06, Vol.24 (6), p.317-319

1993

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Thapsigargin blocks the mobilisation of intracellular calcium caused by activation of human NK1 (long) receptors expressed in chinese hamster ovary cells

Neuroscience letters, 1993-04, Vol.152 (1), p.9-12

1993

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Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor

Molecular pharmacology, 1992-09, Vol.42 (3), p.458-463

1992

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Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345

Nature (London), 1993-03, Vol.362 (6418), p.350-353

1993

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Relative contribution of polar interactions and conformational compatibility to the binding of neurokinin-1 receptor antagonists

Molecular pharmacology, 1996-12, Vol.50 (6), p.1605

1996

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Mutational analysis of neurokinin receptor function

Canadian journal of physiology and pharmacology, 1995-07, Vol.73 (7), p.860

1995

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Use of Bioluminescent Aequorin for the Pharmacological Characterization of 5ht Receptors

Journal of receptors and signal transduction, 1999-11, Vol.19 (6), p.927-938

1999

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Species-Dependent Pharmacological Properties of the Melanocortin-5 Receptor

Journal of receptors and signal transduction, 2000, Vol.20 (1), p.47-59

2000

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