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A new serotonin 2A receptor antagonist with potential benefits in Non-Alcoholic Fatty Liver Disease

Life sciences (1973), 2023-02, Vol.314, p.121315-121315, Article 121315

2023

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Strategies to stabilize cell penetrating peptides for in vivo applications

Therapeutic delivery, 2015-10, Vol.6 (10), p.1171-1194

2015

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Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

The Journal of biological chemistry, 2009-10, Vol.284 (41), p.28392-28400

2009

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Spinophilin acts as a tumor suppressor by regulating Rb phosphorylation

Cell cycle (Georgetown, Tex.), 2011-08, Vol.10 (16), p.2751-2762

2011

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Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition

Cancer letters, 2011-01, Vol.300 (2), p.145-153

2011

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Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1591-1597

2012

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Enhanced serum proteolysis resistance of cell-penetrating peptides

Therapeutic delivery, 2015-02, Vol.6 (2), p.139-147

2015

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MAP17 enhances the malignant behavior of tumor cells through ROS increase

Carcinogenesis (New York), 2007-10, Vol.28 (10), p.2096-2104

2007

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Imidazo[1,2-a]pyrazines as novel PI3K inhibitors

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.1874-1878

2012

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Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (10), p.3460-3466

2012

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MAP17 overexpression is a common characteristic of carcinomas

Carcinogenesis (New York), 2007-08, Vol.28 (8), p.1646-1652

2007

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Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR

Bioorganic & medicinal chemistry letters, 2012-08, Vol.22 (16), p.5208-5214

2012

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Evaluation of Caspase-9b and PP2Acα2 as potential biomarkers for chronic lymphocytic leukemia

Biomarker research, 2016-05, Vol.4 (9), p.9-9, Article 9

2016

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Discovery of Mitogen-Activated Protein Kinase-Interacting Kinase 1 Inhibitors by a Comprehensive Fragment-Oriented Virtual Screening Approach

Journal of medicinal chemistry, 2010-09, Vol.53 (18), p.6618-6628

2010

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Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases

Investigational new drugs, 2013-02, Vol.31 (1), p.66-76

2013

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Extreme sensitivity to Yondelis® (Trabectedin, ET-743) in low passaged sarcoma cell lines correlates with mutated p53

Journal of cellular biochemistry, 2007-02, Vol.100 (2), p.339-348

2007

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Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate

Carcinogenesis (New York), 2007-07, Vol.28 (7), p.1418-1425

2007

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Effect of different baculovirus inactivation procedures on the integrity and immunogenicity of porcine parvovirus-like particles

Vaccine, 2000-11, Vol.19 (7), p.726-734

2000

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Identification of PP2A/Set Binding Sites and Design of Interacting Peptides with Potential Clinical Applications

International journal of peptide research and therapeutics, 2018-12, Vol.24 (4), p.479-488

2018

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Identification of an immunodominant epitope in the C terminus of glycoprotein 5 of porcine reproductive and respiratory syndrome virus

Journal of general virology, 2001-05, Vol.82 (5), p.995-999

2001

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A Modular DNA Carrier Protein Based on the Structure of Diphtheria Toxin Mediates Target Cell-specific Gene Delivery

The Journal of biological chemistry, 1998-04, Vol.273 (15), p.8835-8841

1998

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Oxidation of Sulfhydryl Groups of Ribonuclease Inhibitor in Epithelial Cells Is Sufficient for Its Intracellular Degradation

The Journal of biological chemistry, 1996-08, Vol.271 (31), p.18638-18642

1996

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Membrane localization of all class I PI 3-kinase isoforms suppresses c-Myc-induced apoptosis in Rat1 fibroblasts via Akt

Journal of cellular biochemistry, 2005-08, Vol.95 (5), p.979-989

2005

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Evaluation of Caspase-9b and PP2AcAlpha2 as potential biomarkers for chronic lymphocytic leukemia

Biomarker research, 2016-01, Vol.4

2016

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A new serotonin 2A receptor antagonist with potential benefits in Non-Alcoholic Fatty Liver Disease

Strategies to stabilize cell penetrating peptides for in vivo applications

Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

Spinophilin acts as a tumor suppressor by regulating Rb phosphorylation

Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition

Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors

Enhanced serum proteolysis resistance of cell-penetrating peptides

MAP17 enhances the malignant behavior of tumor cells through ROS increase

Imidazo[1,2-a]pyrazines as novel PI3K inhibitors

Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor

MAP17 overexpression is a common characteristic of carcinomas

Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR

Evaluation of Caspase-9b and PP2Acα2 as potential biomarkers for chronic lymphocytic leukemia

Discovery of Mitogen-Activated Protein Kinase-Interacting Kinase 1 Inhibitors by a Comprehensive Fragment-Oriented Virtual Screening Approach

Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases

Extreme sensitivity to Yondelis® (Trabectedin, ET-743) in low passaged sarcoma cell lines correlates with mutated p53

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate

Effect of different baculovirus inactivation procedures on the integrity and immunogenicity of porcine parvovirus-like particles

Identification of PP2A/Set Binding Sites and Design of Interacting Peptides with Potential Clinical Applications

Identification of an immunodominant epitope in the C terminus of glycoprotein 5 of porcine reproductive and respiratory syndrome virus

A Modular DNA Carrier Protein Based on the Structure of Diphtheria Toxin Mediates Target Cell-specific Gene Delivery

Oxidation of Sulfhydryl Groups of Ribonuclease Inhibitor in Epithelial Cells Is Sufficient for Its Intracellular Degradation

Membrane localization of all class I PI 3-kinase isoforms suppresses c-Myc-induced apoptosis in Rat1 fibroblasts via Akt

Evaluation of Caspase-9b and PP2AcAlpha2 as potential biomarkers for chronic lymphocytic leukemia

Abstract B228: Discovery of 6-Methyl-3-aryl-7,8-dihydro-6H-9-oxa-1,2,3a,4,6-pentaaza-cyclopenta[a]naphthalen-5-ylamine compounds as Pim kinase inhibitors with potent activity in tumoral cell lines and special binding mode

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