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Targeting telomere maintenance mechanisms in cancer therapy

Current pharmaceutical design, 2014-01, Vol.20 (41), p.6359

Folini, M

2014

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Targeting survivin in cancer therapy: fulfilled promises and open questions

Carcinogenesis (New York), 2007-06, Vol.28 (6), p.1133-1139

2007

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miR-205 regulates basement membrane deposition in human prostate: implications for cancer development

Cell death and differentiation, 2012-05, Vol.19 (11), p.1750-1760

2012

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miR-205 regulates basement membrane deposition in human prostate: implications for cancer development

Cell death and differentiation, 2012-11, Vol.19 (11), p.1750-1760

2012

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Targeting telomerase by antisense-based approaches: perspectives for new anti-cancer therapies

Current pharmaceutical design, 2005-04, Vol.11 (9), p.1105

2005

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Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation

British journal of cancer, 2009-03, Vol.100 (5), p.739-746

2009

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Towards the definition of prostate cancer-related microRNAs: where are we now?

Trends in molecular medicine, 2009-09, Vol.15 (9), p.381-390

2009

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Oligomer-mediated modulation of hTERT alternative splicing induces telomerase inhibition and cell growth decline in human prostate cancer cells

Cellular and molecular life sciences : CMLS, 2004-07, Vol.61 (14), p.1764-1774

2004

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Photochemically enhanced delivery of a cell-penetrating peptide nucleic acid conjugate targeting human telomerase reverse transcriptase: effects on telomere status and proliferative potential of human prostate cancer cells

Cell proliferation, 2007-12, Vol.40 (6), p.905-920

2007

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Attenuation of telomerase activity does not increase sensitivity of human melanoma cells to anticancer agents

European journal of cancer (1990), 2000-10, Vol.36 (16), p.2137-2145

2000

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Possible Regulation of Telomerase Activity by Transcription and Alternative Splicing of Telomerase Reverse Transcriptase in Human Melanoma

Journal of investigative dermatology, 2001-06, Vol.116 (6), p.867-873

2001

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Approaches for the inhibition of human telomerase based on the use of peptide nucleic acids and hammerhead ribozymes

Mini reviews in medicinal chemistry, 2003-02, Vol.3 (1), p.51

2003

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535 miR-205-mediated reversal of epithelial–mesenchymal transition modifies the drug sensitivity profile of prostate cancer cells

European journal of cancer supplements, 2010, Vol.8 (7), p.170-171

2010

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Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents

International journal of oncology, 2000-05, Vol.16 (5), p.995

2000

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Silencing of survivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in human prostate cancer cells

Molecular cancer therapeutics, 2006-01, Vol.5 (1), p.179-186

2006

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Ribozyme-mediated attenuation of survivin expression sensitizes human melanoma cells to cisplatin-induced apoptosis

The Journal of clinical investigation, 2002-01, Vol.109 (2), p.285-286

2002

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Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells

European journal of cancer (1990), 2005-03, Vol.41 (4), p.624-634

2005

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Radiosensitization of Human Melanoma Cells by Ribozyme-Mediated Inhibition of Survivin Expression

Journal of investigative dermatology, 2003-04, Vol.120 (4), p.648-654

2003

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256 POSTER SiRNA-mediated Apollon gene silencing induces apoptosis in breast cancer cells via p53 stabilization and caspase-3 activation

European journal of cancer supplements, 2008, Vol.6 (12), p.84-84

2008

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RNA interference-mediated validation of genes involved in telomere maintenance and evasion of apoptosis as cancer therapeutic targets

Methods in molecular biology (Clifton, N.J.), 2009, Vol.487, p.303

2009

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Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance

Neuro-oncology (Charlottesville, Va.), 2012-06, Vol.14 (6), p.736-744

2012

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Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells

Oncogene, 2004-01, Vol.23 (2), p.386-394

2004

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Telomerase Activity in Benign and Malignant Breast Lesions: a Pilot Prospective Study on Fine-Needle Aspirates

JNCI : Journal of the National Cancer Institute, 1998-04, Vol.90 (7), p.537-539

1998

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Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase

Cancer research (Chicago, Ill.), 2003-07, Vol.63 (13), p.3490-3494

2003

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Ribozyme-mediated down-regulation of survivin expression sensitizes human melanoma cells to topotecan in vitro and in vivo

Carcinogenesis (New York), 2004-07, Vol.25 (7), p.1129-1136

2004

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Targeting telomere maintenance mechanisms in cancer therapy

Targeting survivin in cancer therapy: fulfilled promises and open questions

miR-205 regulates basement membrane deposition in human prostate: implications for cancer development

miR-205 regulates basement membrane deposition in human prostate: implications for cancer development

Targeting telomerase by antisense-based approaches: perspectives for new anti-cancer therapies

Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation

Towards the definition of prostate cancer-related microRNAs: where are we now?

Oligomer-mediated modulation of hTERT alternative splicing induces telomerase inhibition and cell growth decline in human prostate cancer cells

Photochemically enhanced delivery of a cell-penetrating peptide nucleic acid conjugate targeting human telomerase reverse transcriptase: effects on telomere status and proliferative potential of human prostate cancer cells

Attenuation of telomerase activity does not increase sensitivity of human melanoma cells to anticancer agents

Possible Regulation of Telomerase Activity by Transcription and Alternative Splicing of Telomerase Reverse Transcriptase in Human Melanoma

Approaches for the inhibition of human telomerase based on the use of peptide nucleic acids and hammerhead ribozymes

535 miR-205-mediated reversal of epithelial–mesenchymal transition modifies the drug sensitivity profile of prostate cancer cells

Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents

Silencing of survivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in human prostate cancer cells

Ribozyme-mediated attenuation of survivin expression sensitizes human melanoma cells to cisplatin-induced apoptosis

Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells

Radiosensitization of Human Melanoma Cells by Ribozyme-Mediated Inhibition of Survivin Expression

256 POSTER SiRNA-mediated Apollon gene silencing induces apoptosis in breast cancer cells via p53 stabilization and caspase-3 activation

RNA interference-mediated validation of genes involved in telomere maintenance and evasion of apoptosis as cancer therapeutic targets

Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance

Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells

Telomerase Activity in Benign and Malignant Breast Lesions: a Pilot Prospective Study on Fine-Needle Aspirates

Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase

Ribozyme-mediated down-regulation of survivin expression sensitizes human melanoma cells to topotecan in vitro and in vivo

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