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Critical Evaluation of the Colocalization Between Calcitonin Gene-Related Peptide, Substance P, Transient Receptor Potential Vanilloid Subfamily Type 1 Immunoreactivities, and Isolectin B4 Binding in Primary Afferent Neurons of the Rat and Mouse

The journal of pain, 2007-03, Vol.8 (3), p.263-272

2007

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Attenuated Cold Sensitivity in TRPM8 Null Mice

Neuron (Cambridge, Mass.), 2007-05, Vol.54 (3), p.379-386

2007

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Mechanistic and functional differentiation of tapentadol and tramadol

Expert opinion on pharmacotherapy, 2012-07, Vol.13 (10), p.1437-1449

2012

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Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Journal of lipid research, 2015-06, Vol.56 (6), p.1153-1171

2015

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Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

The Journal of neuroscience, 2005-03, Vol.25 (12), p.3126-3131

2005

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Erratum: Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Journal of lipid research, 2019-03, Vol.60 (3), p.717-717

2019

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Characterization of the trigeminovascular actions of several adenosine A2A receptor antagonists in an in vivo rat model of migraine

Journal of headache and pain, 2018-05, Vol.19 (1), p.1-10, Article 41

2018

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Revealing Unknown Benefits of Existing Medications to Aid the Discovery of New Treatments for Post‐Traumatic Stress Disorder

Psychiatric research and clinical practice, 2022-03, Vol.4 (1), p.12-20

2022

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Modulation of trigeminal sensory neuron activity by the dual cannabinoid–vanilloid agonists anandamide, N‐arachidonoyl‐dopamine and arachidonyl‐2‐chloroethylamide

British journal of pharmacology, 2004-04, Vol.141 (7), p.1118-1130

2004

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Design and Optimization of Benzimidazole-Containing Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists

Journal of medicinal chemistry, 2011-01, Vol.54 (1), p.233-247

2011

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Sex differences in the role of atypical PKC within the basolateral nucleus of the amygdala in a mouse hyperalgesic priming model

Neurobiology of pain, 2020-08, Vol.8, p.100049-100049, Article 100049

2020

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JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence

The Journal of pharmacology and experimental therapeutics, 2009-04, Vol.329 (1), p.241

2009

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TRPV2 Is Activated by Cannabidiol and Mediates CGRP Release in Cultured Rat Dorsal Root Ganglion Neurons

The Journal of neuroscience, 2008-06, Vol.28 (24), p.6231-6238

2008

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Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1298

2005

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TRPV1 antagonist JNJ-39439335 (mavatrep) demonstrates proof of pharmacology in healthy men: a first-in-human, double-blind, placebo-controlled, randomized, sequential group study

Pain reports, 2016-10, Vol.1 (4), p.e576-e576

2016

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Treatment of trigeminal ganglion neurons in vitro with NGF, GDNF or BDNF: effects on neuronal survival, neurochemical properties and TRPV1-mediated neuropeptide secretion

BMC neuroscience, 2005-01, Vol.6 (1), p.4-4

2005

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JNJ-10450232 (NTM-006), A novel non-opioid with structural similarities to acetaminophen, produces relatively long-lasting analgesia after a single dose in patients undergoing 3rd molar extraction

Regulatory toxicology and pharmacology, 2023-08, p.105480-105480, Article 105480

2023

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Cholinergic modulation of nociceptive responses in vivo and neuropeptide release in vitro at the level of the primary sensory neuron

Pain (Amsterdam), 2004-01, Vol.107 (1-2), p.22

2004

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First-in-human study to evaluate the safety, tolerability and pharmacokinetics of a novel analgesic and antipyretic drug with structural similarity to acetaminophen

Regulatory toxicology and pharmacology, 2022-10, Vol.134, p.105236-105236, Article 105236

2022

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The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL)

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (12), p.127198-127198, Article 127198

2020

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Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses

Regulatory toxicology and pharmacology, 2023-01, p.105334, Article 105334

2023

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Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons

Epilepsy research, 2009-01, Vol.83 (1), p.66-72

2009

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Jeffrey Scott Nye

Neuropsychopharmacology (New York, N.Y.), 2017-07, Vol.42 (8), p.1748-1748

2017

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The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors

Bioorganic & medicinal chemistry letters, 2020-07, Vol.30 (14), p.127243-127243, Article 127243

2020

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Activation Properties of Heterologously Expressed Mammalian TRPV2: EVIDENCE FOR SPECIES DEPENDENCE

The Journal of biological chemistry, 2007-05, Vol.282 (21), p.15894-15902

2007

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Critical Evaluation of the Colocalization Between Calcitonin Gene-Related Peptide, Substance P, Transient Receptor Potential Vanilloid Subfamily Type 1 Immunoreactivities, and Isolectin B4 Binding in Primary Afferent Neurons of the Rat and Mouse

Attenuated Cold Sensitivity in TRPM8 Null Mice

Mechanistic and functional differentiation of tapentadol and tramadol

Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

Erratum: Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Characterization of the trigeminovascular actions of several adenosine A2A receptor antagonists in an in vivo rat model of migraine

Revealing Unknown Benefits of Existing Medications to Aid the Discovery of New Treatments for Post‐Traumatic Stress Disorder

Modulation of trigeminal sensory neuron activity by the dual cannabinoid–vanilloid agonists anandamide, N‐arachidonoyl‐dopamine and arachidonyl‐2‐chloroethylamide

Design and Optimization of Benzimidazole-Containing Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists

Sex differences in the role of atypical PKC within the basolateral nucleus of the amygdala in a mouse hyperalgesic priming model

JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence

TRPV2 Is Activated by Cannabidiol and Mediates CGRP Release in Cultured Rat Dorsal Root Ganglion Neurons

Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention

TRPV1 antagonist JNJ-39439335 (mavatrep) demonstrates proof of pharmacology in healthy men: a first-in-human, double-blind, placebo-controlled, randomized, sequential group study

Treatment of trigeminal ganglion neurons in vitro with NGF, GDNF or BDNF: effects on neuronal survival, neurochemical properties and TRPV1-mediated neuropeptide secretion

JNJ-10450232 (NTM-006), A novel non-opioid with structural similarities to acetaminophen, produces relatively long-lasting analgesia after a single dose in patients undergoing 3rd molar extraction

Cholinergic modulation of nociceptive responses in vivo and neuropeptide release in vitro at the level of the primary sensory neuron

First-in-human study to evaluate the safety, tolerability and pharmacokinetics of a novel analgesic and antipyretic drug with structural similarity to acetaminophen

The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL)

Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses

Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons

Jeffrey Scott Nye

The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors

Activation Properties of Heterologously Expressed Mammalian TRPV2: EVIDENCE FOR SPECIES DEPENDENCE

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