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Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke

PloS one, 2014-01, Vol.9 (1), p.e84767-e84767

2014

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Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease

The Journal of pharmacology and experimental therapeutics, 2020-08, Vol.374 (2), p.342

2020

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Activation of Hypoxia-Inducible Factors in Hyperoxia through Prolyl 4-Hydroxylase Blockade in Cells and Explants of Primate Lung

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (29), p.10212-10217

2005

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Isolation of the Acetylcholinesterase Inhibitor Ungeremine from Nerine bowdenii by Preparative HPLC Coupled On-Line to a Flow Assay System

Biological and Pharmaceutical Bulletin, 2004, Vol.27(11), pp.1804-1809

2004

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Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization

Kidney international, 2010-02, Vol.77 (4), p.312-318

2010

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lmplementation of the prolyl hydroxylase inhibitor Roxadustat (FG‐4592) and its main metabolites into routine doping controls

Drug testing and analysis, 2017-11, Vol.9 (11-12), p.1768-1778

2017

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Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney

Nephrology, dialysis, transplantation, 2008-11, Vol.23 (11), p.3472-3478

2008

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Non-hypoxic Stabilization of Hypoxia-Inducible Factor Alpha (HIF-α): Relevance in Neural Progenitor/Stem Cells

Neurotoxicity research, 2009-05, Vol.15 (4), p.367-380

2009

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Palladium-Mediated 6-endo-trig Intramolecular Cyclization of N-Acryloyl-7-bromoindolines. A Regiochemical Variant of the Intramolecular Heck Reaction

Journal of organic chemistry, 1995-04, Vol.60 (8), p.2312-2313

1995

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Regiochemical control of the ring opening of 1,2-epoxides by means of chelating processes. 5. Synthesis and reactions of some 2,3-epoxy-1-alkanol derivatives

Journal of organic chemistry, 1993-02, Vol.58 (5), p.1221-1227

1993

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Acyclic stereoselection. 52. On the mechanism of Lewis acid mediated nucleophilic substitution reactions of acetals

Journal of organic chemistry, 1990-12, Vol.55 (25), p.6107-6115

1990

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Regiochemical control of the ring-opening of 1,2-epoxides by means of chelating processes. 3. Aminolysis and azidolysis of the cis- and trans-oxides derived from 4-(benzyloxy)cyclohexene

Journal of organic chemistry, 1991-12, Vol.56 (25), p.7043-7048

1991

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RS‐127445: a selective, high affinity, orally bioavailable 5‐HT2B receptor antagonist

British journal of pharmacology, 1999-07, Vol.127 (5), p.1075-1082

1999

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Concise Synthesis of Narcissus Pyrrolophenanthridine Alkaloids: Vasconine, Assoanine and Oxoassoanine

Journal of organic chemistry, 1994-06, Vol.59 (12), p.3497-3499

1994

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Total Synthesis of Amaryllidaceae Pyrrolophenanthridinium Alkaloids via the Ziegler−Ullmann Reaction: Tortuosine, Criasbetaine, and Ungeremine

Journal of organic chemistry, 2000-05, Vol.65 (10), p.3227-3230

2000

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Regiochemical control of the ring opening of 1,2-epoxides by means of chelating processes. 4. Synthesis and reactions of the cis- and trans-oxides derived from 3-[(benzyloxy)methyl]cyclohexene

Journal of organic chemistry, 1992-03, Vol.57 (6), p.1713-1718

1992

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Substituent-directed alkyl addition reactions of epoxides. 1. Applications to the synthesis of 3-hydroxy-4-methylalkanoic acids

Journal of organic chemistry, 1989-07, Vol.54 (15), p.3588-3596

1989

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Nucleophilic Aromatic Substitution Reactions of Novel 5-(2-Methoxyphenyl)tetrazole Derivatives with Organolithium Reagents

Journal of organic chemistry, 1999-12, Vol.64 (25), p.9301-9306

1999

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Directed metalation and new synthetic transformations of 5-aryltetrazoles

Tetrahedron letters, 1991-11, Vol.32 (47), p.6857-6860

Flippin, Lee A.

1991

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Synthesis of Mexiletine Stereoisomers and Related Compounds via SNAr Nucleophilic Substitution of a Cr(CO)3-Complexed Aromatic Fluoride

Journal of organic chemistry, 1999-04, Vol.64 (9), p.3373-3375

1999

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Structure of the fatty acid component of an antibiotic cyclodepsipeptide complex from the genus Fusarium

Journal of organic chemistry, 1989-06, Vol.54 (13), p.3006-3007

1989

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Total Synthesis of (±)-Roserine

Journal of organic chemistry, 1997-12, Vol.62 (26), p.9305-9313

1997

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A convenient method for the reduction of ozonides to alcohols with borane-dimethyl sulfide complex

Journal of organic chemistry, 1989-03, Vol.54 (6), p.1430-1432

1989

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Total Synthesis of (±)-Roserine

Journal of organic chemistry, 1998-10, Vol.63 (22), p.8080-8080

1998

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Regiochemical control of the ring-opening of 1,2-epoxides by means of chelating processes. 2. Synthesis and reactions of the cis- and trans-oxides of 4-[(benzyloxy)methyl]cyclohexene, 3-cyclohexenemethanol, and methyl 3-cyclohexenecarboxylate

Journal of organic chemistry, 1992-02, Vol.57 (5), p.1405-1412

1992

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Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke

Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease

Activation of Hypoxia-Inducible Factors in Hyperoxia through Prolyl 4-Hydroxylase Blockade in Cells and Explants of Primate Lung

Isolation of the Acetylcholinesterase Inhibitor Ungeremine from Nerine bowdenii by Preparative HPLC Coupled On-Line to a Flow Assay System

Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization

lmplementation of the prolyl hydroxylase inhibitor Roxadustat (FG‐4592) and its main metabolites into routine doping controls

Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney

Non-hypoxic Stabilization of Hypoxia-Inducible Factor Alpha (HIF-α): Relevance in Neural Progenitor/Stem Cells

Palladium-Mediated 6-endo-trig Intramolecular Cyclization of N-Acryloyl-7-bromoindolines. A Regiochemical Variant of the Intramolecular Heck Reaction

Regiochemical control of the ring opening of 1,2-epoxides by means of chelating processes. 5. Synthesis and reactions of some 2,3-epoxy-1-alkanol derivatives

Acyclic stereoselection. 52. On the mechanism of Lewis acid mediated nucleophilic substitution reactions of acetals

Regiochemical control of the ring-opening of 1,2-epoxides by means of chelating processes. 3. Aminolysis and azidolysis of the cis- and trans-oxides derived from 4-(benzyloxy)cyclohexene

RS‐127445: a selective, high affinity, orally bioavailable 5‐HT2B receptor antagonist

Concise Synthesis of Narcissus Pyrrolophenanthridine Alkaloids: Vasconine, Assoanine and Oxoassoanine

Total Synthesis of Amaryllidaceae Pyrrolophenanthridinium Alkaloids via the Ziegler−Ullmann Reaction: Tortuosine, Criasbetaine, and Ungeremine

Regiochemical control of the ring opening of 1,2-epoxides by means of chelating processes. 4. Synthesis and reactions of the cis- and trans-oxides derived from 3-[(benzyloxy)methyl]cyclohexene

Substituent-directed alkyl addition reactions of epoxides. 1. Applications to the synthesis of 3-hydroxy-4-methylalkanoic acids

Nucleophilic Aromatic Substitution Reactions of Novel 5-(2-Methoxyphenyl)tetrazole Derivatives with Organolithium Reagents

Directed metalation and new synthetic transformations of 5-aryltetrazoles

Synthesis of Mexiletine Stereoisomers and Related Compounds via SNAr Nucleophilic Substitution of a Cr(CO)3-Complexed Aromatic Fluoride

Structure of the fatty acid component of an antibiotic cyclodepsipeptide complex from the genus Fusarium

Total Synthesis of (±)-Roserine

A convenient method for the reduction of ozonides to alcohols with borane-dimethyl sulfide complex

Total Synthesis of (±)-Roserine

Regiochemical control of the ring-opening of 1,2-epoxides by means of chelating processes. 2. Synthesis and reactions of the cis- and trans-oxides of 4-[(benzyloxy)methyl]cyclohexene, 3-cyclohexenemethanol, and methyl 3-cyclohexenecarboxylate

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