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Introduction to the Thematic Review Series: Seeing 2020: lipids and lipid-soluble molecules in the eye

Journal of lipid research, 2021-01, Vol.62, p.100007, Article 100007

Fliesler, Steven J.

2021

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Cholesterol homeostasis in the vertebrate retina: biology and pathobiology

Journal of lipid research, 2021-01, Vol.62, p.100057, Article 100057

2021

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Reassessing the suitability of ARPE-19 cells as a valid model of native RPE biology

Experimental eye research, 2022-06, Vol.219, p.109046-109046, Article 109046

2022

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In Memoriam: G. Stephen (Steve) Tint, PhD (1935-2022)

Journal of lipid research, 2023-08, Vol.64 (8), p.100421, Article 100421

2023

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Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention

Molecules (Basel, Switzerland), 2018-10, Vol.23 (10), p.2720

2018

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Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (39), p.E4086-E4095

2014

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Endoplasmic reticulum stress and the unfolded protein responses in retinal degeneration

Experimental eye research, 2014-08, Vol.125, p.30-40

2014

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Cells Special Issue: "The Molecular and Cellular Basis of Retinal Diseases"

Cells (Basel, Switzerland), 2023-07, Vol.12 (15), p.1933

2023

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Bottlenecks in the Investigation of Retinal Sterol Homeostasis

Biomolecules (Basel, Switzerland), 2024-03, Vol.14 (3), p.341

2024

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Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome

International journal of molecular sciences, 2021-02, Vol.22 (5), p.2339

2021

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Inherited Retinal Degeneration Caused by Dehydrodolichyl Diphosphate Synthase Mutation-Effect of an ALG6 Modifier Variant

International journal of molecular sciences, 2024-01, Vol.25 (2), p.1004

2024

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Vertebrate Animal Models of RP59: Current Status and Future Prospects

International journal of molecular sciences, 2022-11, Vol.23 (21), p.13324

2022

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Generation and validation of a conditional knockout mouse model for the study of the Smith-Lemli-Opitz syndrome

Journal of lipid research, 2021, Vol.62, p.100002, Article 100002

2021

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Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome

Autophagy, 2018-10, Vol.14 (10), p.1796-1817

2018

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Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome

Scientific reports, 2018-01, Vol.8 (1), p.1286-13, Article 1286

2018

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A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

PloS one, 2009-04, Vol.4 (4), p.e5290-e5290

2009

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A Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission

Cell death & disease, 2023-07, Vol.14 (7), p.420-420, Article 420

2023

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A Dpagt1 Missense Variant Causes Degenerative Retinopathy without Myasthenic Syndrome in Mice

International journal of molecular sciences, 2022-10, Vol.23 (19), p.12005

2022

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Novel oxysterols observed in tissues and fluids of AY9944-treated rats: a model for Smith-Lemli-Opitz syndrome

Journal of lipid research, 2011-10, Vol.52 (10), p.1810-1820

2011

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Monitoring basal autophagy in the retina utilizing CAG-mRFP-EGFP-MAP1LC3B reporter mouse: technical and biological considerations

Autophagy, 2022-05, Vol.18 (5), p.1187-1201

2022

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EDITOR’S PERSPECTIVE: On the verge of translation: Combined cholesterol-antioxidant supplementation as a potential therapeutic intervention for Smith-Lemli-Opitz syndrome

Experimental eye research, 2021-01, Vol.202, p.108390-108390, Article 108390

Fliesler, Steven J.

2021

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Early-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency

Investigative ophthalmology & visual science, 2011-05, Vol.52 (6), p.3557-3566

2011

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Lack of Overt Retinal Degeneration in a K42E Dhdds Knock-In Mouse Model of RP59

Cells (Basel, Switzerland), 2020-04, Vol.9 (4), p.896

2020

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Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis

Frontiers in cell and developmental biology, 2020-11, Vol.8, p.560266-560266

2020

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The subretinal drusenoid deposit (SDD) of age-related macular degeneration (AMD) may have a specific and strong association with high-risk vascular diseases (HRVDs)

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), 2024-01, Vol.13 (1), p.100035-100035, Article 100035

Fliesler, Steven J.

2024

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Introduction to the Thematic Review Series: Seeing 2020: lipids and lipid-soluble molecules in the eye

Cholesterol homeostasis in the vertebrate retina: biology and pathobiology

Reassessing the suitability of ARPE-19 cells as a valid model of native RPE biology

In Memoriam: G. Stephen (Steve) Tint, PhD (1935-2022)

Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development

Endoplasmic reticulum stress and the unfolded protein responses in retinal degeneration

Cells Special Issue: "The Molecular and Cellular Basis of Retinal Diseases"

Bottlenecks in the Investigation of Retinal Sterol Homeostasis

Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome

Inherited Retinal Degeneration Caused by Dehydrodolichyl Diphosphate Synthase Mutation-Effect of an ALG6 Modifier Variant

Vertebrate Animal Models of RP59: Current Status and Future Prospects

Generation and validation of a conditional knockout mouse model for the study of the Smith-Lemli-Opitz syndrome

Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome

Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome

A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

A Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission

A Dpagt1 Missense Variant Causes Degenerative Retinopathy without Myasthenic Syndrome in Mice

Novel oxysterols observed in tissues and fluids of AY9944-treated rats: a model for Smith-Lemli-Opitz syndrome

Monitoring basal autophagy in the retina utilizing CAG-mRFP-EGFP-MAP1LC3B reporter mouse: technical and biological considerations

EDITOR’S PERSPECTIVE: On the verge of translation: Combined cholesterol-antioxidant supplementation as a potential therapeutic intervention for Smith-Lemli-Opitz syndrome

Early-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency

Lack of Overt Retinal Degeneration in a K42E Dhdds Knock-In Mouse Model of RP59

Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis

The subretinal drusenoid deposit (SDD) of age-related macular degeneration (AMD) may have a specific and strong association with high-risk vascular diseases (HRVDs)

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