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LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival

Nature communications, 2018-10, Vol.9 (1), p.4055-10, Article 4055

2018

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Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite

Cell chemical biology, 2019-05, Vol.26 (5), p.674-685.e6

2019

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Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (8), p.2467-2472

2015

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signaling phospholipid PIP₃ creates a new interaction surface on the nuclear receptor SF-1

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15054-15059

2014

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Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19830-19844

2013

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Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.16927-16931

2011

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surface on the androgen receptor that allosterically regulates coactivator binding

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (41), p.16074-16079

2007

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The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable

PloS one, 2014-06, Vol.9 (6), p.e99440

2014

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Structural basis of coactivation of liver receptor homolog-1 by β-catenin

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (1), p.143-148

2012

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Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.11878-11883

2011

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Structural and functional insight into TAF1–TAF7, a subcomplex of transcription factor II D

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.9103-9108

2014

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Recognition and accommodation at the androgen receptor coactivator binding interface

PLoS biology, 2004-09, Vol.2 (9), p.E274-E274

2004

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structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18390-18395

2008

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Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (15), p.4666-4671

2015

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Disulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2)

PloS one, 2016-07, Vol.11 (7), p.e0159316

2016

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Conformation Switching of Clathrin Light Chain Regulates Clathrin Lattice Assembly

Developmental cell, 2010-05, Vol.18 (5), p.854-861

2010

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A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

eLife, 2015-12, Vol.4

2015

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The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling

PloS one, 2015-07, Vol.10 (7), p.e0134015-e0134015

2015

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Structural Basis for Ligand-Independent Activation of the Orphan Nuclear Receptor LRH-1

Molecular cell, 2003-06, Vol.11 (6), p.1575-1585

2003

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An atomic model of the thin filament in the relaxed and Ca2+-activated states

Journal of molecular biology, 2006-03, Vol.357 (3), p.707-717

2006

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Actin Binding by Hip1 (Huntingtin-interacting Protein 1) and Hip1R (Hip1-related Protein) Is Regulated by Clathrin Light Chain

The Journal of biological chemistry, 2008-11, Vol.283 (47), p.32870-32879

2008

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Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

Molecular endocrinology (Baltimore, Md.), 2009-01, Vol.23 (1), p.25-34

2009

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Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors

Science (American Association for the Advancement of Science), 1998-06, Vol.280 (5370), p.1747-1749

1998

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The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor

The Journal of biological chemistry, 2005-03, Vol.280 (9), p.8060-8068

2005

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NUCLEAR-RECEPTOR LIGANDS AND LIGAND-BINDING DOMAINS

Annual review of biochemistry, 1999-01, Vol.68 (1), p.559-581

1999

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LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival

Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite

Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs

signaling phospholipid PIP₃ creates a new interaction surface on the nuclear receptor SF-1

Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1

Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation

surface on the androgen receptor that allosterically regulates coactivator binding

The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable

Structural basis of coactivation of liver receptor homolog-1 by β-catenin

Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells

Structural and functional insight into TAF1–TAF7, a subcomplex of transcription factor II D

Recognition and accommodation at the androgen receptor coactivator binding interface

structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells

Disulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2)

Conformation Switching of Clathrin Light Chain Regulates Clathrin Lattice Assembly

A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling

Structural Basis for Ligand-Independent Activation of the Orphan Nuclear Receptor LRH-1

An atomic model of the thin filament in the relaxed and Ca2+-activated states

Actin Binding by Hip1 (Huntingtin-interacting Protein 1) and Hip1R (Hip1-related Protein) Is Regulated by Clathrin Light Chain

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors

The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor

NUCLEAR-RECEPTOR LIGANDS AND LIGAND-BINDING DOMAINS

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