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Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition

Drug resistance updates, 2021-12, Vol.59, p.100795-100795, Article 100795

2021

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ABC transporters in cancer: more than just drug efflux pumps

Nature reviews. Cancer, 2010-02, Vol.10 (2), p.147

2010

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A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4), p.971-981

2017

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The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression

Oncotarget, 2016-02, Vol.7 (8), p.8663-8675

2016

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The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Nature communications, 2024-02, Vol.15 (1), p.1385-1385, Article 1385

2024

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Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1

PLoS pathogens, 2010-12, Vol.6 (12), p.e1001236

2010

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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18081-18087

2008

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CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma

British journal of cancer, 2020-09, Vol.123 (7), p.1101-1113

2020

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ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

JNCI : Journal of the National Cancer Institute, 2011-08, Vol.103 (16), p.1236-1251

2011

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MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

Cancer research (Chicago, Ill.), 2016-06, Vol.76 (12), p.3604-3617

2016

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High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

Biochemical pharmacology, 2014-09, Vol.91 (1), p.97-108

2014

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Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen

Biochemical pharmacology, 2015-02, Vol.93 (3), p.380-388

2015

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ABC transporters as mediators of drug resistance and contributors to cancer cell biology

Drug resistance updates, 2016-05, Vol.26, p.1-9

2016

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Controlling the cell death mediators Bax and Bak: puzzles and conundrums

Cell cycle (Georgetown, Tex.), 2008-01, Vol.7 (1), p.39-44

2008

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Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

Cell death & disease, 2021-03, Vol.12 (3), p.268-18, Article 268

2021

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Generation of Orthotopic and Subcutaneous Patient-Derived Xenograft Models from Diverse Clinical Tissue Samples of Pediatric Extracranial Solid Tumors

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2806, p.55

2024

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Too many targets, not enough patients: rethinking neuroblastoma clinical trials

Nature reviews. Cancer, 2018-06, Vol.18 (6), p.389

2018

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Mouse models of high-risk neuroblastoma

Cancer and metastasis reviews, 2020-03, Vol.39 (1), p.261-274

2020

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Quantification of vincristine and tariquidar by liquid chromatography‐tandem mass spectrometry in mouse whole blood using volumetric absorptive microsampling for pharmacokinetic applications

Journal of separation science, 2022-07, Vol.45 (14), p.2508-2519

2022

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

Genes & development, 2005-06, Vol.19 (11), p.1294-1305

2005

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GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators

The FEBS journal, 2022-07, Vol.289 (13), p.3854-3875

2022

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Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition

Oncogene, 2020-04, Vol.39 (17), p.3555-3570

2020

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Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression

Cancer research (Chicago, Ill.), 2020-09, Vol.80 (17), p.3706-3718

2020

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Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN‐amplified neuroblastoma

International journal of cancer, 2020-10, Vol.147 (7), p.1928-1938

2020

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Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition

ABC transporters in cancer: more than just drug efflux pumps

A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers

The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma

ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen

ABC transporters as mediators of drug resistance and contributors to cancer cell biology

Controlling the cell death mediators Bax and Bak: puzzles and conundrums

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

Generation of Orthotopic and Subcutaneous Patient-Derived Xenograft Models from Diverse Clinical Tissue Samples of Pediatric Extracranial Solid Tumors

Too many targets, not enough patients: rethinking neuroblastoma clinical trials

Mouse models of high-risk neuroblastoma

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

Quantification of vincristine and tariquidar by liquid chromatography‐tandem mass spectrometry in mouse whole blood using volumetric absorptive microsampling for pharmacokinetic applications

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators

Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition

Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression

Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN‐amplified neuroblastoma

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