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Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acids

Organic & biomolecular chemistry, 2016-01, Vol.14 (44), p.10371-10385

2016

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N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors

Organic & biomolecular chemistry, 2014-11, Vol.12 (44), p.8977-8996

2014

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1-(1-Carboxy-methyl-1,4-anhydro-2,3-O-isopropyl-idene-α-d-erythrofuranos-yl)thymine

Acta crystallographica. Section E, Structure reports online, 2010-01, Vol.66 (Pt 2), p.o404-o404

2010

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Glucose analog inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes

Biochemistry (Easton), 1991-10, Vol.30 (42), p.10101-10116

1991

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3,4- O -Isopropylidene-2- C -methyl- D -galactonolactone

Acta crystallographica. Section E, Structure reports online, 2010-02, Vol.66 (2), p.o406-o407

2010

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Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acidsElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob01549b

2016-11

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The structural basis of the inhibition of human α-mannosidases by azafuranose analogues of mannose

Biochemical journal, 1993-03, Vol.290 (3), p.743-749

1993

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Homonojirimycin Isomers and N-Alkylated Homonojirimycins: Structural and Conformational Basis of Inhibition of Glycosidases

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2565-2571

1998

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Purification to homogeneity of Charonia lampas α-fucosidase by using sequential ligand-affinity chromatography

Biochemical journal, 1991-10, Vol.279 (1), p.189-195

1991

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Sugar mimics from sugar lactones

Pure and applied chemistry, 1998-02, Vol.70 (2), p.279-284

1998

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Anomeric specificity of D-xylose isomerase

Biochemistry (Easton), 1992-12, Vol.31 (48), p.12211-12218

1992

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Nitrogen-Containing Furanose and Pyranose Analogues from Hyacinthus orientalis

Journal of natural products (Washington, D.C.), 1998-05, Vol.61 (5), p.625-628

1998

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Aminosugar Derivatives as Potential Anti-Human Immunodeficiency Virus Agents

Proceedings of the National Academy of Sciences - PNAS, 1988-12, Vol.85 (23), p.9229-9233

1988

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Polyhydroxylated pyrrolidine and piperidine alkaloids from Adenophora triphylla var. japonica (Campanulaceae)

Phytochemistry (Oxford), 2000-02, Vol.53 (3), p.379-382

2000

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Inhibition of HIV replication by amino-sugar derivatives

FEBS letters, 1988-09, Vol.237 (1), p.128-132

1988

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(1 R ,2 R ,3 S ,6a S ,7 R ,8 R ,9 S ,12a S )-1,2,3,7,8,9-Hexahydroxyperhydrodipyrido[1,2- a :1′,2′- d ]pyrazine-6,12-dione

Acta crystallographica. Section E, Structure reports online, 2010-04, Vol.66 (4), p.o853-o853

2010

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Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta

Phytochemistry (Oxford), 1997-09, Vol.46 (2), p.255-259

1997

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The design of potential antidiabetic drugs : experimental investigation of a number of β-D-glucose analogue inhibitors of glycogen phosphorylase

European journal of drug metabolism and pharmacokinetics, 1994-07, Vol.19 (3), p.185-192

1994

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3,4-O-Isopropyl-idene-2-C-methyl-d-galactonolactone

Acta crystallographica. Section E, Structure reports online, 2010-01, Vol.66 (Pt 2), p.o406-o407

2010

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N‐acetyl‐β‐D‐glucopyranosylamine: A potent T‐state inhibitor of glycogen phosphorylase. A comparison with α‐D‐glucose

Protein science, 1995-12, Vol.4 (12), p.2469-2477

1995

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Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection

Acta crystallographica. Section D, Biological crystallography., 1995-07, Vol.51 (4), p.458-472

1995

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6-Azido-3-O-benzyl-6-de-oxy-N,N-diethyl-1,2-O-isopropyl-idene-d-glycero-α-d-gluco-heptofuran-uronamide

Acta crystallographica. Section E, Structure reports online, 2010-12, Vol.67 (Pt 1), p.o38-o39

2010

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(1R,2R,3S,6aS,7R,8R,9S,12aS)-1,2,3,7,8,9-Hexahydroxy-perhydro-dipyrido[1,2-a:1',2'-d]pyrazine-6,12-dione

Acta crystallographica. Section E, Structure reports online, 2010-03, Vol.66 (Pt 4), p.o853-o853

2010

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Polyhydroxylated pyrrolidines from sugar lactones: synthesis of 1,4-dideoxy-1,4-imino-D-glucitol from D-galactonolactone and syntheses of 1,4-dideoxy-1,4-imino-D-allitol, 1,4-dideoxy-1,4-imino-D-ribitol, and (2S,3R,4S)-3,4-dihydroxyproline from D-gulonolactone

Tetrahedron, 1988, Vol.44 (9), p.2637-2647

1988

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Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acids

N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors

1-(1-Carboxy-methyl-1,4-anhydro-2,3-O-isopropyl-idene-α-d-erythrofuranos-yl)thymine

Glucose analog inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes

3,4- O -Isopropylidene-2- C -methyl- D -galactonolactone

Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acidsElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob01549b

The structural basis of the inhibition of human α-mannosidases by azafuranose analogues of mannose

Homonojirimycin Isomers and N-Alkylated Homonojirimycins: Structural and Conformational Basis of Inhibition of Glycosidases

Purification to homogeneity of Charonia lampas α-fucosidase by using sequential ligand-affinity chromatography

Sugar mimics from sugar lactones

Anomeric specificity of D-xylose isomerase

Nitrogen-Containing Furanose and Pyranose Analogues from Hyacinthus orientalis

Aminosugar Derivatives as Potential Anti-Human Immunodeficiency Virus Agents

Polyhydroxylated pyrrolidine and piperidine alkaloids from Adenophora triphylla var. japonica (Campanulaceae)

Inhibition of HIV replication by amino-sugar derivatives

(1 R ,2 R ,3 S ,6a S ,7 R ,8 R ,9 S ,12a S )-1,2,3,7,8,9-Hexahydroxyperhydrodipyrido[1,2- a :1′,2′- d ]pyrazine-6,12-dione

Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta

The design of potential antidiabetic drugs : experimental investigation of a number of β-D-glucose analogue inhibitors of glycogen phosphorylase

3,4-O-Isopropyl-idene-2-C-methyl-d-galactonolactone

N‐acetyl‐β‐D‐glucopyranosylamine: A potent T‐state inhibitor of glycogen phosphorylase. A comparison with α‐D‐glucose

Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection

6-Azido-3-O-benzyl-6-de-oxy-N,N-diethyl-1,2-O-isopropyl-idene-d-glycero-α-d-gluco-heptofuran-uronamide

(1R,2R,3S,6aS,7R,8R,9S,12aS)-1,2,3,7,8,9-Hexahydroxy-perhydro-dipyrido[1,2-a:1',2'-d]pyrazine-6,12-dione

Polyhydroxylated pyrrolidines from sugar lactones: synthesis of 1,4-dideoxy-1,4-imino-D-glucitol from D-galactonolactone and syntheses of 1,4-dideoxy-1,4-imino-D-allitol, 1,4-dideoxy-1,4-imino-D-ribitol, and (2S,3R,4S)-3,4-dihydroxyproline from D-gulonolactone

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