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Endothelial Glycocalyx Impairment in Disease

The American journal of pathology, 2020-04, Vol.190 (4), p.768-780

2020

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Abundance and size of hyaluronan in naked mole-rat tissues and plasma

Scientific reports, 2021-04, Vol.11 (1), p.7951-7951, Article 7951

2021

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Hyaluronidase 1 Deficiency Preserves Endothelial Function and Glycocalyx Integrity in Early Streptozotocin-Induced Diabetes

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2742-2753

2016

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Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia

Aging clinical and experimental research, 2016-02, Vol.28 (1), p.47-58

2016

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Hyaluronidase 1 deficiency decreases bone mineral density in mice

Scientific reports, 2022-06, Vol.12 (1), p.10142-10142, Article 10142

2022

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Murine Hyaluronidase 2 Deficiency Results in Extracellular Hyaluronan Accumulation and Severe Cardiopulmonary Dysfunction

The Journal of biological chemistry, 2013-01, Vol.288 (1), p.520-528

2013

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Hyaluronan Metabolism in Human Keratinocytes and Atopic Dermatitis Skin Is Driven by a Balance of Hyaluronan Synthases 1 and 3

Journal of investigative dermatology, 2014-08, Vol.134 (8), p.2174-2182

2014

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Two Novel Functions of Hyaluronidase-2 (Hyal2) Are Formation of the Glycocalyx and Control of CD44-ERM Interactions

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33495-33508

2009

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Cascading renal injury after brain death: Unveiling glycocalyx alteration and the potential protective role of tacrolimus

Frontiers in cell and developmental biology, 2024-08, Vol.12, p.1449209

2024

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Endothelial Glycocalyx Impairment in Disease: Focus on Hyaluronan Shedding

The American journal of pathology, 2020-04, Vol.190 (4), p.768-780

2020

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Subcellular Trafficking and Activity of Hyal‐1 and Its Processed Forms in Murine Macrophages

Traffic (Copenhagen, Denmark), 2014-05, Vol.15 (5), p.500-515

2014

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Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase

Biochemical and biophysical research communications, 2011-07, Vol.411 (1), p.175-179

2011

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Respective roles of hyaluronidases 1 and 2 in endogenous hyaluronan turnover

The FASEB journal, 2016-06, Vol.30 (6), p.2108-2114

2016

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The regulatory landscape for actively personalized cancer immunotherapies

Nature biotechnology, 2013-10, Vol.31 (10), p.880-882

2013

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Skeletal and hematological anomalies in HYAL2-deficient mice: a second type of mucopolysaccharidosis IX?

The FASEB journal, 2008-12, Vol.22 (12), p.4316-4326

2008

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The European Regulatory Environment of RNA-Based Vaccines

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1499, p.203

2017

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Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy

Haematologica (Roma), 2015-08, Vol.100 (8), p.1023

2015

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Deletion of TNFAIP6 Gene in Human Keratinocytes Demonstrates a Role for TSG-6 to Retain Hyaluronan Inside Epidermis

JID innovations, 2021-12, Vol.1 (4), p.100054-100054, Article 100054

2021

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Randomized Dose-Response Study of the New Dual Endothelin Receptor Antagonist Aprocitentan in Hypertension

Hypertension (Dallas, Tex. 1979), 2020-04, Vol.75 (4), p.956-965

2020

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0458 The Sleep Diary Questionnaire: An Analysis of Meaningful Change in Subjective Total Sleep Time Using Phase 2 and Phase 3 Clinical Trial Data

Sleep (New York, N.Y.), 2022-05, Vol.45 (Supplement_1), p.A203-A203

2022

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Improving clinical trial sampling for future research - an international approach: outcomes and next steps from the DIA future use sampling workshop 2011

Pharmacogenomics, 2013-01, Vol.14 (1), p.103-112

2013

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Keratitis in Dry Eye Disease and Topical Ciclosporin A

Ocular immunology and inflammation, 2017-08, Vol.25 (4), p.577-586

2017

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Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Kidney international, 2015-07, Vol.88 (1), p.17-27

2015

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348 Absence of Withdrawal Symptoms and Rebound Insomnia Upon Discontinuation of Daridorexant in Patients with Insomnia

Sleep (New York, N.Y.), 2021-05, Vol.44 (Supplement_2), p.A139-A139

2021

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Balancing early market access to new drugs with the need for benefit/risk data: a mounting dilemma

Nature reviews. Drug discovery, 2008-10, Vol.7 (10), p.818-826

2008

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Endothelial Glycocalyx Impairment in Disease

Abundance and size of hyaluronan in naked mole-rat tissues and plasma

Hyaluronidase 1 Deficiency Preserves Endothelial Function and Glycocalyx Integrity in Early Streptozotocin-Induced Diabetes

Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia

Hyaluronidase 1 deficiency decreases bone mineral density in mice

Murine Hyaluronidase 2 Deficiency Results in Extracellular Hyaluronan Accumulation and Severe Cardiopulmonary Dysfunction

Hyaluronan Metabolism in Human Keratinocytes and Atopic Dermatitis Skin Is Driven by a Balance of Hyaluronan Synthases 1 and 3

Two Novel Functions of Hyaluronidase-2 (Hyal2) Are Formation of the Glycocalyx and Control of CD44-ERM Interactions

Cascading renal injury after brain death: Unveiling glycocalyx alteration and the potential protective role of tacrolimus

Endothelial Glycocalyx Impairment in Disease: Focus on Hyaluronan Shedding

Subcellular Trafficking and Activity of Hyal‐1 and Its Processed Forms in Murine Macrophages

Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase

Respective roles of hyaluronidases 1 and 2 in endogenous hyaluronan turnover

The regulatory landscape for actively personalized cancer immunotherapies

Skeletal and hematological anomalies in HYAL2-deficient mice: a second type of mucopolysaccharidosis IX?

The European Regulatory Environment of RNA-Based Vaccines

Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy

Deletion of TNFAIP6 Gene in Human Keratinocytes Demonstrates a Role for TSG-6 to Retain Hyaluronan Inside Epidermis

Randomized Dose-Response Study of the New Dual Endothelin Receptor Antagonist Aprocitentan in Hypertension

0458 The Sleep Diary Questionnaire: An Analysis of Meaningful Change in Subjective Total Sleep Time Using Phase 2 and Phase 3 Clinical Trial Data

Improving clinical trial sampling for future research - an international approach: outcomes and next steps from the DIA future use sampling workshop 2011

Keratitis in Dry Eye Disease and Topical Ciclosporin A

Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

348 Absence of Withdrawal Symptoms and Rebound Insomnia Upon Discontinuation of Daridorexant in Patients with Insomnia

Balancing early market access to new drugs with the need for benefit/risk data: a mounting dilemma

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