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Astrocytes from Na+-K+-Cl- cotransporter-null mice exhibit absence of swelling and decrease in EAA release

American Journal of Physiology: Cell Physiology, 2002-05, Vol.282 (5), p.C1147-C1160

2002

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Mice Lacking the Basolateral Na-K-2Cl Cotransporter Have Impaired Epithelial Chloride Secretion and Are Profoundly Deaf

The Journal of biological chemistry, 1999-09, Vol.274 (38), p.26946-26955

1999

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Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na+-K+-2Cl- cotransporter

American journal of physiology. Heart and circulatory physiology, 2002-11, Vol.283 (5), p.H1846-H1855

2002

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An alternate pathway of cAMP-stimulated Cl− secretion across the NKCC1-null murine duodenum

Gastroenterology (New York, N.Y. 1943), 2002-08, Vol.123 (2), p.531-541

2002

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Effect of selective LRRK2 kinase inhibition on nonhuman primate lung

Science translational medicine, 2015-02, Vol.7 (273), p.273ra15

2015

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Mouse Mammary Epithelial Cells Express the Na-K-Cl Cotransporter, NKCC1: Characterization, Localization, and Involvement in Ductal Development and Morphogenesis

Molecular endocrinology (Baltimore, Md.), 2002-06, Vol.16 (6), p.1309-1321

2002

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An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines

Cancer research (Chicago, Ill.), 2004-06, Vol.64 (11), p.3761-3766

2004

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Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7686-7695

2012

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A multiplex branched DNA assay for parallel quantitative gene expression profiling

Analytical biochemistry, 2006-05, Vol.352 (1), p.50-60

2006

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Mitigation of Acetylcholine Esterase Activity in the 1,7-Diazacarbazole Series of Inhibitors of Checkpoint Kinase 1

Journal of medicinal chemistry, 2015-06, Vol.58 (12), p.5053-5074

2015

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Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900

Molecular cancer therapeutics, 2013-10, Vol.12 (10), p.1968-1980

2013

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Abstract 1598: RM-046, a first-in-class, mutant-selective, and oral KRASQ61H(ON) inhibitor that drives tumor regression in preclinical models and validates KRASQ61H as a therapeutic target

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1598-1598

2023

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Identification of GNE-293, a potent and selective PI3Kδ inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity

Bioorganic & medicinal chemistry letters, 2013-09, Vol.23 (17), p.4953-4959

2013

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Phenotype Resembling Gitelman's Syndrome in Mice Lacking the Apical Na+-Cl− Cotransporter of the Distal Convoluted Tubule

The Journal of biological chemistry, 1998-10, Vol.273 (44), p.29150-29155

1998

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Identification of GNE-293, a potent and selective PI3KI' inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity

Bioorganic & medicinal chemistry letters, 2013-09, Vol.23 (17), p.4953-4959

2013

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Exploratory cardiovascular safety pharmacology in the lead-optimization of novel small molecule kinase inhibitors

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.e31-e31

2011

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Small Interfering RNA and Gene Expression Analysis Using a Multiplex Branched DNA Assay without RNA Purification

Journal of biomolecular screening, 2005-09, Vol.10 (6), p.549-556

2005

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Cloning, renal distribution, and regulation of the rat Na+-HCO3- cotransporter

The American journal of physiology, 1998-06, Vol.274 (6), p.F1119

1998

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The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase

Cell and tissue research, 2002-09, Vol.309 (3), p.369-380

2002

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Astrocytes from Na+-K+-C1- cotransporter-null mice exhibit absence of swelling and decrease in EAA release

American Journal of Physiology: Cell Physiology, 2002-05, Vol.51 (5), p.C1147

2002

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Astrocytes from Na+-K+-Cl- cotransporter-null mice exhibit absence of swelling and decrease in EAA release

American Journal of Physiology: Cell Physiology, 2002, Vol.51 (5), p.C1147-C1160

2002

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Molecular and physiological studies of electrolyte and fluid transport perturbations in NKCC1 and NHE3 -deficient mice

Flagella, Michael

2001

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ProQuest

Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na+-K+-2Cl- cotransporter

American journal of physiology. Heart and circulatory physiology, 2002-11, Vol.52 (5), p.H1846-H1855

2002

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CAMP stimulated anion secretion across NKCC1 knockout intestine

Gastroenterology (New York, N.Y. 1943), 2000-04, Vol.118 (4), p.A605-A605

2000

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Astrocytes from Na+-K+-Cl- cotransporter-null mice exhibit absence of swelling and decrease in EAA release

Mice Lacking the Basolateral Na-K-2Cl Cotransporter Have Impaired Epithelial Chloride Secretion and Are Profoundly Deaf

Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na+-K+-2Cl- cotransporter

An alternate pathway of cAMP-stimulated Cl− secretion across the NKCC1-null murine duodenum

Effect of selective LRRK2 kinase inhibition on nonhuman primate lung

Mouse Mammary Epithelial Cells Express the Na-K-Cl Cotransporter, NKCC1: Characterization, Localization, and Involvement in Ductal Development and Morphogenesis

Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors

An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines

Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

A multiplex branched DNA assay for parallel quantitative gene expression profiling

Mitigation of Acetylcholine Esterase Activity in the 1,7-Diazacarbazole Series of Inhibitors of Checkpoint Kinase 1

Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900

Abstract 1598: RM-046, a first-in-class, mutant-selective, and oral KRASQ61H(ON) inhibitor that drives tumor regression in preclinical models and validates KRASQ61H as a therapeutic target

Identification of GNE-293, a potent and selective PI3Kδ inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity

Phenotype Resembling Gitelman's Syndrome in Mice Lacking the Apical Na+-Cl− Cotransporter of the Distal Convoluted Tubule

Identification of GNE-293, a potent and selective PI3KI' inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity

Exploratory cardiovascular safety pharmacology in the lead-optimization of novel small molecule kinase inhibitors

Small Interfering RNA and Gene Expression Analysis Using a Multiplex Branched DNA Assay without RNA Purification

Cloning, renal distribution, and regulation of the rat Na+-HCO3- cotransporter

The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase

Astrocytes from Na+-K+-C1- cotransporter-null mice exhibit absence of swelling and decrease in EAA release

Astrocytes from Na+-K+-Cl- cotransporter-null mice exhibit absence of swelling and decrease in EAA release

Molecular and physiological studies of electrolyte and fluid transport perturbations in NKCC1 and NHE3 -deficient mice

Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na+-K+-2Cl- cotransporter

CAMP stimulated anion secretion across NKCC1 knockout intestine

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