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Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

Journal of medicinal chemistry, 2003-02, Vol.46 (4), p.453-456

2003

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4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.4923-4926

2000

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8-Hydroxy-3,4-dihydropyrrolo[1,2- a]pyrazine-1(2 H)-one HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6511-6515

2007

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Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5595-5599

2007

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A Naphthyridine Carboxamide Provides Evidence for Discordant Resistance between Mechanistically Identical Inhibitors of HIV-1 Integrase

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (31), p.11233-11238

2004

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Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogs of 3-aminopyridin-2(1H)-one

Journal of medicinal chemistry, 1992-10, Vol.35 (21), p.3792-3802

1992

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2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2922-2925

1991

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Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogs

Journal of medicinal chemistry, 1993-04, Vol.36 (8), p.953-966

1993

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Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one

Journal of medicinal chemistry, 1993, Vol.36 (2), p.249-255

1993

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Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors

Bioorganic & medicinal chemistry letters, 2000-09, Vol.10 (17), p.1943-1948

2000

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Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages

Bioorganic & medicinal chemistry, 1994-09, Vol.2 (9), p.939-947

1994

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Tetrahydrofuran synthesis via free radical mediated addition of functionalized alkenes to aryl vinyl oxiranes

Tetrahedron, 1989, Vol.45 (10), p.2969-2977

1989

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An efficient synthesis of γ-alkylated E-olefin dipeptide isosteres

Tetrahedron letters, 1995-05, Vol.36 (20), p.3461-3464

1995

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A Convenient and Versatile Synthesis of Chiral Aliphatic and Allylic Amines

Synthesis (Stuttgart), 1990, Vol.1990 (6), p.453-454

1990

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Synthesis of 3-Alkyl-6-bromo-4,5-E-hexenoate

Synthetic communications, 1996-09, Vol.26 (18), p.3431-3442

1996

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Detection and attribution of wildfire pollution in the Arctic and northern midlatitudes using a network of Fourier-transform infrared spectrometers and GEOS-Chem

Atmospheric chemistry and physics, 2020-11, Vol.20 (21), p.12813-12851

2020

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Timeless standards for species delimitation

Zootaxa, 2016-07, Vol.4137 (1), p.121

2016

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An 11-year record of XCO.sub.2 estimates derived from GOSAT measurements using the NASA ACOS version 9 retrieval algorithm

Earth system science data, 2022-01, Vol.14 (1), p.325

2022

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An 11-year record of XCO 2 estimates derived from GOSAT measurements using the NASA ACOS version 9 retrieval algorithm

Earth system science data, 2022-01, Vol.14 (1), p.325-360

2022

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Comparisons of the Orbiting Carbon Observatory-2 X.sub.CO.sub.2 measurements with TCCON

Atmospheric measurement techniques, 2017-06, Vol.10 (6), p.2209

2017

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Comparisons of the Orbiting Carbon Observatory-2 (OCO-2) X CO 2 measurements with TCCON

Atmospheric measurement techniques, 2017-06, Vol.10 (6), p.2209-2238

2017

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Identifying parametric controls and dependencies in integrated assessment models using global sensitivity analysis

Environmental modelling & software : with environment data news, 2014-09, Vol.59, p.10-29

2014

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Ovarian changes in women with morbid obesity

Obstetrics and gynecology (New York. 1953), 1974-12, Vol.44 (6), p.839

1974

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Ether derivatives of a progestin and estrogen in monthly dosage

Clinical pharmacology and therapeutics, 1973-05, Vol.14 (3), p.455-461

1973

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Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells

8-Hydroxy-3,4-dihydropyrrolo[1,2- a]pyrazine-1(2 H)-one HIV-1 integrase inhibitors

Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors

10-Hydroxy-7,8-dihydropyrazino[1′,2′:1,5]pyrrolo[2,3- d]pyridazine-1,9(2 H,6 H)-diones: Potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against integrase mutants

A Naphthyridine Carboxamide Provides Evidence for Discordant Resistance between Mechanistically Identical Inhibitors of HIV-1 Integrase

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogs of 3-aminopyridin-2(1H)-one

2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogs

Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one

Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors

Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages

Tetrahydrofuran synthesis via free radical mediated addition of functionalized alkenes to aryl vinyl oxiranes

An efficient synthesis of γ-alkylated E-olefin dipeptide isosteres

A Convenient and Versatile Synthesis of Chiral Aliphatic and Allylic Amines

Synthesis of 3-Alkyl-6-bromo-4,5-E-hexenoate

Detection and attribution of wildfire pollution in the Arctic and northern midlatitudes using a network of Fourier-transform infrared spectrometers and GEOS-Chem

Timeless standards for species delimitation

An 11-year record of XCO.sub.2 estimates derived from GOSAT measurements using the NASA ACOS version 9 retrieval algorithm

An 11-year record of XCO 2 estimates derived from GOSAT measurements using the NASA ACOS version 9 retrieval algorithm

Comparisons of the Orbiting Carbon Observatory-2 X.sub.CO.sub.2 measurements with TCCON

Comparisons of the Orbiting Carbon Observatory-2 (OCO-2) X CO 2 measurements with TCCON

Identifying parametric controls and dependencies in integrated assessment models using global sensitivity analysis

Ovarian changes in women with morbid obesity

Ether derivatives of a progestin and estrogen in monthly dosage

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