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Involvement of NADPH: cytochrome P450 reductase in the activation of indoloquinone EO9 to free radical and DNA damaging species

Biochemical pharmacology, 2001-08, Vol.62 (4), p.461-468

2001

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Reduction of the indoloquinone anticancer drug EO9 by purified DT-diaphorase: a detailed kinetic study and analysis of metabolites

Biochemical pharmacology, 1998-09, Vol.56 (5), p.613-621

1998

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Involvement of NADPH: cytochrome P450 reductase in the activation of indoloquinone EO9 to free radical and DNA damaging species56Abbreviations: EORTC, European Organisation for the Research and Treatment of Cancer; DMPO, 5,5-dimethyl-1-pyrroline-1-oxide; and AN and AH, hyperfine-splitting constants for nitrogen and hydrogen, respectively

Biochemical pharmacology, 2001-08, Vol.62 (4), p.461-468

2001

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Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)

Journal of clinical oncology, 2021-03, Vol.39 (7), p.822-835

2021

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Health Status of Children Alive 10 Years after Pediatric Liver Transplantation Performed in the US and Canada: Report of the Studies of Pediatric Liver Transplantation Experience

The Journal of pediatrics, 2012-05, Vol.160 (5), p.820-826.e3

2012

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Very Early Administration of Progesterone for Acute Traumatic Brain Injury

The New England journal of medicine, 2014-12, Vol.371 (26), p.2457-2466

2014

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Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

Nature communications, 2020-04, Vol.11 (1), p.1712-1712, Article 1712

2020

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External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase

Cancers, 2020-03, Vol.12 (4), p.798

2020

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Age-related delay in visual and auditory evoked responses is mediated by white- and grey-matter differences

Nature communications, 2017-06, Vol.8 (1), p.15671-15671, Article 15671

2017

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The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study protocol: a cross-sectional, lifespan, multidisciplinary examination of healthy cognitive ageing

BMC neurology, 2014-10, Vol.14 (1), p.204-204, Article 204

2014

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A phase-1 dose escalation and expansion study of EP0031, a next-generation selective RET inhibitor (SRI), in patients with SRI-naïve or pretreated advanced RET-altered NSCLC and other tumors

Journal of clinical oncology, 2024-06, Vol.42 (16_suppl), p.8556-8556

2024

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Multiple determinants of lifespan memory differences

Scientific reports, 2016-09, Vol.6 (1), p.32527-32527, Article 32527

2016

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Strong and specific associations between cardiovascular risk factors and white matter micro- and macrostructure in healthy aging

Neurobiology of aging, 2019-02, Vol.74, p.46-55

2019

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Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities

Scientific reports, 2023-01, Vol.13 (1), p.978-978, Article 978

2023

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Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking

Nature communications, 2014-12, Vol.5 (1), p.5658-5658, Article 5658

2014

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Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits

Nature communications, 2016-10, Vol.7 (1), p.13034-13034, Article 13034

2016

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Age-related reduction in motor adaptation: brain structural correlates and the role of explicit memory

Neurobiology of aging, 2020-06, Vol.90, p.13-23

2020

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Hyperintense Vessels on Acute Stroke Fluid-Attenuated Inversion Recovery Imaging: Associations With Clinical and Other MRI Findings

Stroke (1970), 2012-11, Vol.43 (11), p.2957-2961

2012

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Preserved cognitive functions with age are determined by domain-dependent shifts in network responsivity

Nature communications, 2017-05, Vol.8 (1), p.14743-14743, Article 14743

2017

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Physical Activity Predicts Population-Level Age-Related Differences in Frontal White Matter

The journals of gerontology. Series A, Biological sciences and medical sciences, 2020-01, Vol.75 (2), p.236-243

2020

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Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group

Acta neuropathologica, 2014-02, Vol.127 (2), p.189-201

2014

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Perceptual and conceptual processing of visual objects across the adult lifespan

Scientific reports, 2019-09, Vol.9 (1), p.13771-13, Article 13771

2019

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Hundreds of millions of people in the tropics need both wild harvests and other forms of economic development for their well-being

One earth (Cambridge, Mass.), 2024-02, Vol.7 (2), p.311-324

2024

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Involvement of NADPH: cytochrome P450 reductase in the activation of indoloquinone EO9 to free radical and DNA damaging species

Reduction of the indoloquinone anticancer drug EO9 by purified DT-diaphorase: a detailed kinetic study and analysis of metabolites

Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)

Health Status of Children Alive 10 Years after Pediatric Liver Transplantation Performed in the US and Canada: Report of the Studies of Pediatric Liver Transplantation Experience

DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4·5 h of symptom onset (PRE-FLAIR): a multicentre observational study

Very Early Administration of Progesterone for Acute Traumatic Brain Injury

Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase

Age-related delay in visual and auditory evoked responses is mediated by white- and grey-matter differences

The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study protocol: a cross-sectional, lifespan, multidisciplinary examination of healthy cognitive ageing

A phase-1 dose escalation and expansion study of EP0031, a next-generation selective RET inhibitor (SRI), in patients with SRI-naïve or pretreated advanced RET-altered NSCLC and other tumors

Multiple determinants of lifespan memory differences

Strong and specific associations between cardiovascular risk factors and white matter micro- and macrostructure in healthy aging

Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities

Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking

Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits

Age-related reduction in motor adaptation: brain structural correlates and the role of explicit memory

Hyperintense Vessels on Acute Stroke Fluid-Attenuated Inversion Recovery Imaging: Associations With Clinical and Other MRI Findings

Preserved cognitive functions with age are determined by domain-dependent shifts in network responsivity

Physical Activity Predicts Population-Level Age-Related Differences in Frontal White Matter

Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group

Perceptual and conceptual processing of visual objects across the adult lifespan

Hundreds of millions of people in the tropics need both wild harvests and other forms of economic development for their well-being

Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma

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