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Role of the HER2 [Ile655Val] genetic polymorphism in tumorogenesis and in the risk of trastuzumab-related cardiotoxicity

Annals of oncology, 2007-08, Vol.18 (8), p.1335-1341

2007

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Pharmacological background of EGFR targeting

Annals of oncology, 2004-07, Vol.15 (7), p.1007-1012

2004

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Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity

British journal of cancer, 2004-01, Vol.90 (2), p.526-534

2004

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Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: A brake to apoptosis in HeLa human carcinoma cells

Cancer research (Chicago, Ill.), 2001-11, Vol.61 (21), p.7785-7791

2001

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Molecular mechanisms underlying the interaction between ZD1839 ('Iressa') and cisplatin 5-fluorouracil

British journal of cancer, 2003-08, Vol.89 (3), p.585-592

2003

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Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity

Journal of clinical oncology, 1995-07, Vol.13 (7), p.1663-1670

1995

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ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity: Rational basis for a new combination therapy with capecitabine

Clinical cancer research, 2003-10, Vol.9 (13), p.4735-4742

2003

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A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

European journal of cancer (1990), 1994, Vol.30A (10), p.1517-1522

1994

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Response of endothelial cells to a dual tyrosine kinase receptor inhibition combined with irradiation

Molecular cancer therapeutics, 2005-12, Vol.4 (12), p.1962-1971

2005

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Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: results on human colon cancer cell lines

British journal of cancer, 2001-02, Vol.84 (4), p.579-585

2001

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Gefitinib–trastuzumab combination on hormone-refractory prostate cancer xenograft

European journal of cancer (1990), 2005-07, Vol.41 (10), p.1467-1473

2005

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Dual HER 1-2 targeting of hormone-refractory prostate cancer by ZD1839 and trastuzumab

European journal of cancer (1990), 2004-12, Vol.40 (18), p.2837-2844

2004

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Search for the optimal schedule for the oxaliplatin/5-fluorouracil association modulated or not by folinic acid: preclinical data

Clinical cancer research, 1998-10, Vol.4 (10), p.2529-2535

1998

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Combination of irinotecan (CPT11) and 5-fluorouracil with an analysis of cellular determinants of drug activity

Biochemical pharmacology, 1998-11, Vol.56 (10), p.1315-1322

1998

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Lack of contribution of dihydrofluorouracil and α-fluoro-β-alanine to the cytotoxicity of 5′-deoxy-5-fluorouridine on human keratinocytes

Anti-cancer drugs, 2004-11, Vol.15 (10), p.969-974

2004

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Taxotere–5′-deoxy-5-fluorouridine combination on hormone-refractory human prostate cancer cells

Anti-cancer drugs, 2005-03, Vol.16 (3), p.309-316

2005

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Oxaliplatin–5-Fluorouracil and Ionizing Radiation

Oncology, 2003-01, Vol.64 (3), p.280-287

2003

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Dihydropyrimidine dehydrogenase: a tumoral target for fluorouracil modulation

Clinical cancer research, 1995-09, Vol.1 (9), p.991-996

1995

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Cell growth inhibitory effects of caulerpenyne, a sesquiterpenoid from the marine algae Caulerpa taxifolia

Anticancer research, 1995-09, Vol.15 (5B), p.2155

1995

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Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal 5-fluorouracil efficacy: Experimental data

European journal of cancer (1990), 1997-05, Vol.33 (6), p.950-959

1997

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Dual modulation of 5-fluorouracil cytotoxicity using folinic acid with a dihydropyrimidine dehydrogenase inhibitor

Biochemical pharmacology, 1997-06, Vol.53 (11), p.1703-1709

1997

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Cytotoxic effects of two gamma linoleic salts (lithium gammalinolenate or meglumine gammalinolenate) alone or associated with a nitrosourea: an experimental study on human glioblastoma cell lines

Anti-cancer drugs, 1999-04, Vol.10 (4), p.413-418

1999

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Tamoxifen metabolism: pharmacokinetic and in vitro study

British journal of cancer, 1989-07, Vol.60 (1), p.30-35

1989

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Variable intrinsic sensitivity of human tumor cell lines to raltitrexed (Tomudex®) and folylpolyglutamate synthetase activity

Anti-cancer drugs, 1999-06, Vol.10 (5), p.505-510

1999

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Effects of prolonged exposure to cisplatin on cytotoxicity and intracellular drug concentration

European journal of cancer (1990), 1992, Vol.28 (1), p.82-86

1992

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Role of the HER2 [Ile655Val] genetic polymorphism in tumorogenesis and in the risk of trastuzumab-related cardiotoxicity

Pharmacological background of EGFR targeting

Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity

Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: A brake to apoptosis in HeLa human carcinoma cells

Molecular mechanisms underlying the interaction between ZD1839 ('Iressa') and cisplatin 5-fluorouracil

Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity

ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity: Rational basis for a new combination therapy with capecitabine

A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

Response of endothelial cells to a dual tyrosine kinase receptor inhibition combined with irradiation

Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: results on human colon cancer cell lines

Gefitinib–trastuzumab combination on hormone-refractory prostate cancer xenograft

Dual HER 1-2 targeting of hormone-refractory prostate cancer by ZD1839 and trastuzumab

Search for the optimal schedule for the oxaliplatin/5-fluorouracil association modulated or not by folinic acid: preclinical data

Combination of irinotecan (CPT11) and 5-fluorouracil with an analysis of cellular determinants of drug activity

Lack of contribution of dihydrofluorouracil and α-fluoro-β-alanine to the cytotoxicity of 5′-deoxy-5-fluorouridine on human keratinocytes

Taxotere–5′-deoxy-5-fluorouridine combination on hormone-refractory human prostate cancer cells

Oxaliplatin–5-Fluorouracil and Ionizing Radiation

Dihydropyrimidine dehydrogenase: a tumoral target for fluorouracil modulation

Cell growth inhibitory effects of caulerpenyne, a sesquiterpenoid from the marine algae Caulerpa taxifolia

Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal 5-fluorouracil efficacy: Experimental data

Dual modulation of 5-fluorouracil cytotoxicity using folinic acid with a dihydropyrimidine dehydrogenase inhibitor

Cytotoxic effects of two gamma linoleic salts (lithium gammalinolenate or meglumine gammalinolenate) alone or associated with a nitrosourea: an experimental study on human glioblastoma cell lines

Tamoxifen metabolism: pharmacokinetic and in vitro study

Variable intrinsic sensitivity of human tumor cell lines to raltitrexed (Tomudex®) and folylpolyglutamate synthetase activity

Effects of prolonged exposure to cisplatin on cytotoxicity and intracellular drug concentration

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