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Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs

Cell reports (Cambridge), 2015-09, Vol.12 (9), p.1385-1390

2015

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Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis

American journal of respiratory and critical care medicine, 2020-01, Vol.201 (2), p.198-211

2020

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Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (17), p.E1723-E1730

2014

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Establishment of the early cilia preassembly protein complex during motile ciliogenesis

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (6), p.E1221-E1228

2018

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Lymphoid Regeneration from Gene-Corrected SCID-X1 Subject-Derived iPSCs

Cell stem cell, 2015-04, Vol.16 (4), p.367-372

2015

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CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro

International journal of cancer, 2018-12, Vol.143 (12), p.3169-3180

2018

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PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells

American Journal of Physiology: Cell Physiology, 2012-01, Vol.302 (2), p.C405-C411

2012

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Brief Report: Efficient Generation of Hematopoietic Precursors and Progenitors from Human Pluripotent Stem Cell Lines

Stem cells (Dayton, Ohio), 2011-07, Vol.29 (7), p.1158-1164

2011

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Pathophysiology of voltage-gated K + channels in vascular smooth muscle cells: Modulation by protein kinases

Progress in biophysics and molecular biology, 2010-09, Vol.103 (1), p.95-101

2010

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Intermittent Reprogramming: A Breath of Fresh Air for Lung Regeneration

Cell stem cell, 2017-12, Vol.21 (6), p.712-714

Firth, Amy L.

2017

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Blockade of voltage-dependent K+ current in rabbit coronary arterial smooth muscle cells by the tricyclic antidepressant clomipramine

Journal of pharmacological sciences, 2018-05, Vol.137 (1), p.61-66

2018

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Adenylyl Cyclase Type 6 Deletion Decreases Left Ventricular Function via Impaired Calcium Handling

Circulation (New York, N.Y.), 2008, Vol.117 (1), p.61-69

2008

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Alterations of voltage-dependent K+ channels in the mesenteric artery during the early and chronic phases of diabetes

Clinical and experimental pharmacology & physiology, 2016-09, Vol.43 (9), p.808-817

2016

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Idiopathic pulmonary arterial hypertension

Disease models & mechanisms, 2010-05, Vol.3 (5-6), p.268-273

2010

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Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells

American journal of physiology. Lung cellular and molecular physiology, 2007-10, Vol.293 (4), p.L952-L959

2007

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The anti-diabetic drug dapagliflozin induces vasodilation via activation of PKG and Kv channels

Life sciences (1973), 2018-03, Vol.197, p.46-55

2018

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Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells

iScience, 2020-05, Vol.23 (5), p.101083, Article 101083

2020

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Application of iPSC to Modelling of Respiratory Diseases

Advances in experimental medicine and biology, 2020, Vol.1237, p.1-16

2020

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Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels

Pulmonary Circulation, 2011-01, Vol.1 (1), p.48-71

2011

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Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart

Biochemical and biophysical research communications, 2011-02, Vol.405 (3), p.349-355

2011

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Thrombin‐mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension

Physiological reports, 2013-12, Vol.1 (7), p.e00190-n/a

2013

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Hypoxia Selectively Inhibits KCNA5 Channels in Pulmonary Artery Smooth Muscle Cells

Annals of the New York Academy of Sciences, 2009-10, Vol.1177 (1), p.101-111

2009

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Direct effect of protein kinase C inhibitors on cardiovascular ion channels

BMB Reports, 2011, 44(9), , pp.559-565

2011

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Chronic exposure to fibrin and fibrinogen differentially regulates intracellular Ca2+ in human pulmonary arterial smooth muscle and endothelial cells

American journal of physiology. Lung cellular and molecular physiology, 2009-06, Vol.296 (6), p.L979-L986

2009

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Thrombin-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells

American journal of physiology. Lung cellular and molecular physiology, 2008-12, Vol.295 (6), p.L1048-L1055

2008

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Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs

Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis

Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells

Establishment of the early cilia preassembly protein complex during motile ciliogenesis

Lymphoid Regeneration from Gene-Corrected SCID-X1 Subject-Derived iPSCs

CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro

PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells

Brief Report: Efficient Generation of Hematopoietic Precursors and Progenitors from Human Pluripotent Stem Cell Lines

Pathophysiology of voltage-gated K + channels in vascular smooth muscle cells: Modulation by protein kinases

Intermittent Reprogramming: A Breath of Fresh Air for Lung Regeneration

Blockade of voltage-dependent K+ current in rabbit coronary arterial smooth muscle cells by the tricyclic antidepressant clomipramine

Adenylyl Cyclase Type 6 Deletion Decreases Left Ventricular Function via Impaired Calcium Handling

Alterations of voltage-dependent K+ channels in the mesenteric artery during the early and chronic phases of diabetes

Idiopathic pulmonary arterial hypertension

Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells

The anti-diabetic drug dapagliflozin induces vasodilation via activation of PKG and Kv channels

Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells

Application of iPSC to Modelling of Respiratory Diseases

Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels

Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart

Thrombin‐mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension

Hypoxia Selectively Inhibits KCNA5 Channels in Pulmonary Artery Smooth Muscle Cells

Direct effect of protein kinase C inhibitors on cardiovascular ion channels

Chronic exposure to fibrin and fibrinogen differentially regulates intracellular Ca2+ in human pulmonary arterial smooth muscle and endothelial cells

Thrombin-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells

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