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Phytochemical regulation of the tumor suppressive microRNA, miR-34a, by p53-dependent and independent responses in human breast cancer cells

Molecular carcinogenesis, 2016-05, Vol.55 (5), p.486-498

2016

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Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression

The Journal of biological chemistry, 2009-01, Vol.284 (4), p.2203-2213

2009

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Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells

BMC biology, 2014-09, Vol.12 (1), p.72, Article 72

2014

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Therapeutic targeting of replicative immortality

Seminars in cancer biology, 2015-12, Vol.35 (S), p.S104-S128

2015

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Bcl-2 family-mediated apoptotic effects of 3,3′-diindolylmethane (DIM) in human breast cancer cells

Biochemical pharmacology, 2002-03, Vol.63 (6), p.1085-1097

2002

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Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK

American journal of physiology. Renal physiology, 2001-04, Vol.280 (4), p.F675-F682

2001

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Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells

Molecular endocrinology (Baltimore, Md.), 2000-08, Vol.14 (8), p.1283-1300

2000

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Expression of the Serum- and Glucocorticoid-inducible Protein Kinase, Sgk, Is a Cell Survival Response to Multiple Types of Environmental Stress Stimuli in Mammary Epithelial Cells

The Journal of biological chemistry, 2003-02, Vol.278 (8), p.5871-5882

2003

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Indole‐3‐carbinol inhibits MDA‐MB‐231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity

International journal of cancer, 2009-05, Vol.124 (10), p.2294-2302

2009

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The Dietary Phytochemical Indole-3-Carbinol Is a Natural Elastase Enzymatic Inhibitor That Disrupts Cyclin E Protein Processing

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (50), p.19750-19755

2008

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The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation

Molecular cancer research, 2014-11, Vol.12 (11), p.1621-1634

2014

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BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype

Cancer biology & therapy, 2010-08, Vol.10 (4), p.397-405

2010

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SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport

American journal of physiology. Renal physiology, 2001-02, Vol.280 (2), p.F303-F313

2001

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Anticancer activities of artemisinin and its bioactive derivatives

Expert reviews in molecular medicine, 2009-10, Vol.11, p.e32-e32, Article e32

2009

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1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/β-catenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of microphthalmia-associated transcription factor isoform-M

Carcinogenesis (New York), 2017-12, Vol.38 (12), p.1207-1217

2017

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Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signaling

Anti-cancer drugs, 2014-03, Vol.25 (3), p.270-281

2014

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Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

Biochemical pharmacology, 2017-03, Vol.127, p.13-27

2017

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Estrogen receptor β inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest

Cancer research (Chicago, Ill.), 2004, Vol.64 (1), p.423-428

2004

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Indole-3-Carbinol (I3C) Inhibits Cyclin-dependent Kinase-2 Function in Human Breast Cancer Cells by Regulating the Size Distribution, Associated Cyclin E Forms, and Subcellular Localization of the CDK2 Protein Complex

The Journal of biological chemistry, 2005-03, Vol.280 (10), p.8756-8764

2005

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Indole‐3‐carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells

International journal of cancer, 2006-02, Vol.118 (4), p.857-868

2006

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Selective glucocorticoid control of Rho kinase isoforms regulate cell–cell interactions

Biochemical and biophysical research communications, 2007-03, Vol.354 (2), p.603-607

2007

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Inhibition of oncogenic BRAF activity by indole‐3‐carbinol disrupts microphthalmia‐associated transcription factor expression and arrests melanoma cell proliferation

Molecular carcinogenesis, 2017-01, Vol.56 (1), p.49-61

2017

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Minireview: Regulation of Gap Junction Dynamics by Nuclear Hormone Receptors and Their Ligands

Molecular endocrinology (Baltimore, Md.), 2012-11, Vol.26 (11), p.1798-1807

2012

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DEVD-NucView488: a novel class of enzyme substrates for real-time detection of caspase-3 activity in live cells

The FASEB journal, 2008-07, Vol.22 (7), p.2243-2252

2008

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3,3'-Diindolylmethane is a novel mitochondrial H(+)-ATP synthase inhibitor that can induce p21(Cip1/Waf1) expression by induction of oxidative stress in human breast cancer cells

Cancer research (Chicago, Ill.), 2006-05, Vol.66 (9), p.4880

2006

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Phytochemical regulation of the tumor suppressive microRNA, miR-34a, by p53-dependent and independent responses in human breast cancer cells

Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression

Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells

Therapeutic targeting of replicative immortality

Bcl-2 family-mediated apoptotic effects of 3,3′-diindolylmethane (DIM) in human breast cancer cells

Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK

Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells

Expression of the Serum- and Glucocorticoid-inducible Protein Kinase, Sgk, Is a Cell Survival Response to Multiple Types of Environmental Stress Stimuli in Mammary Epithelial Cells

Indole‐3‐carbinol inhibits MDA‐MB‐231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity

The Dietary Phytochemical Indole-3-Carbinol Is a Natural Elastase Enzymatic Inhibitor That Disrupts Cyclin E Protein Processing

The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation

BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype

SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport

Anticancer activities of artemisinin and its bioactive derivatives

1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/β-catenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of microphthalmia-associated transcription factor isoform-M

Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signaling

Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

Estrogen receptor β inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest

Indole-3-Carbinol (I3C) Inhibits Cyclin-dependent Kinase-2 Function in Human Breast Cancer Cells by Regulating the Size Distribution, Associated Cyclin E Forms, and Subcellular Localization of the CDK2 Protein Complex

Indole‐3‐carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells

Selective glucocorticoid control of Rho kinase isoforms regulate cell–cell interactions

Inhibition of oncogenic BRAF activity by indole‐3‐carbinol disrupts microphthalmia‐associated transcription factor expression and arrests melanoma cell proliferation

Minireview: Regulation of Gap Junction Dynamics by Nuclear Hormone Receptors and Their Ligands

DEVD-NucView488: a novel class of enzyme substrates for real-time detection of caspase-3 activity in live cells

3,3'-Diindolylmethane is a novel mitochondrial H(+)-ATP synthase inhibitor that can induce p21(Cip1/Waf1) expression by induction of oxidative stress in human breast cancer cells

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