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Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

Nature, 2008-01, Vol.451 (7175), p.211-215

2008

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SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (52), p.20828-20833

2008

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Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

Nature medicine, 2007-05, Vol.13 (5), p.579-586

2007

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Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation

Nature medicine, 2010-08, Vol.16 (8), p.897-902

2010

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IDO Mediates TLR9-Driven Protection from Experimental Autoimmune Diabetes

The Journal of immunology (1950), 2009-11, Vol.183 (10), p.6303-6312

2009

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Kynurenine Pathway Enzymes in Dendritic Cells Initiate Tolerogenesis in the Absence of Functional IDO

Journal of Immunology, 2006-07, Vol.177 (1), p.130-137

2006

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A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

The Journal of experimental medicine, 2003-07, Vol.198 (1), p.153-160

2003

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Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

Nature immunology, 2011-09, Vol.12 (9), p.870

2011

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CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice

The Journal of experimental medicine, 2004-10, Vol.200 (8), p.1051-1062

2004

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Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

International immunology, 2002-01, Vol.14 (1), p.65-68

2002

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Functional Plasticity of Dendritic Cell Subsets as Mediated by CD40 Versus B7 Activation

The Journal of immunology (1950), 2003-09, Vol.171 (5), p.2581-2587

2003

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The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

Journal of Immunology, 2006-06, Vol.176 (11), p.6752-6761

2006

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CD40 Ligation Ablates the Tolerogenic Potential of Lymphoid Dendritic Cells

The Journal of immunology (1950), 2001-01, Vol.166 (1), p.277-283

2001

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CTLA-4-Ig regulates tryptophan catabolism in vivo

Nature immunology, 2002-11, Vol.3 (11), p.1097-1101

2002

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Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells

The Journal of immunology (1950), 2008-10, Vol.181 (8), p.5194-5198

2008

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Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12

European Journal of Immunology, 2005-11, Vol.35 (11), p.3111-3118

2005

Volltextzugriff (PDF)

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone

The Journal of experimental medicine, 2009-10, Vol.206 (11), p.2511-2526

2009

Volltextzugriff (PDF)

T cell apoptosis by kynurenines

Advances in experimental medicine and biology, 2003, Vol.527, p.183

2003

Volltextzugriff (PDF)

IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

Immunity (Cambridge, Mass.), 1998-09, Vol.9 (3), p.315-323

1998

Volltextzugriff (PDF)

Tryptophan catabolism generates autoimmune-preventive regulatory T cells

Transplant Immunology, 2006-12, Vol.17 (1), p.58-60

2006

Volltextzugriff (PDF)

Th1 and Th2 Cell Clones to a Poorly Immunogenic Tumor Antigen Initiate CD8+ T Cell-Dependent Tumor Eradication In Vivo

The Journal of immunology (1950), 2000-11, Vol.165 (10), p.5495-5501

2000

Volltextzugriff (PDF)

Autocrine IL-12 Is Involved in Dendritic Cell Modulation Via CD40 Ligation

The Journal of immunology (1950), 1999-09, Vol.163 (5), p.2517-2521

1999

Volltextzugriff (PDF)

CD40 Ligand and CTLA-4 Are Reciprocally Regulated in the Th1 Cell Proliferative Response Sustained by CD8+ Dendritic Cells

The Journal of immunology (1950), 2002-08, Vol.169 (3), p.1182-1188

2002

Volltextzugriff (PDF)

CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum− or helper peptides in priming for skin test reactivity to a P815AB‐related peptide

European journal of immunology, 1995-10, Vol.25 (10), p.2797-2802

1995

Volltextzugriff (PDF)

Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma

The Journal of immunology (1950), 2001-07, Vol.167 (1), p.221-227

2001

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Indoleamine-Pyrrole 2,3,-Dioxygenase - Metabolism
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Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation

IDO Mediates TLR9-Driven Protection from Experimental Autoimmune Diabetes

Kynurenine Pathway Enzymes in Dendritic Cells Initiate Tolerogenesis in the Absence of Functional IDO

A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice

Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

Functional Plasticity of Dendritic Cell Subsets as Mediated by CD40 Versus B7 Activation

The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

CD40 Ligation Ablates the Tolerogenic Potential of Lymphoid Dendritic Cells

CTLA-4-Ig regulates tryptophan catabolism in vivo

Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells

Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone

T cell apoptosis by kynurenines

IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

Tryptophan catabolism generates autoimmune-preventive regulatory T cells

Th1 and Th2 Cell Clones to a Poorly Immunogenic Tumor Antigen Initiate CD8+ T Cell-Dependent Tumor Eradication In Vivo

Autocrine IL-12 Is Involved in Dendritic Cell Modulation Via CD40 Ligation

CD40 Ligand and CTLA-4 Are Reciprocally Regulated in the Th1 Cell Proliferative Response Sustained by CD8+ Dendritic Cells

CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum− or helper peptides in priming for skin test reactivity to a P815AB‐related peptide

Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma

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