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Six Years (2012–2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2‐Pyridone Compounds

Chemical record, 2018-12, Vol.18 (12), p.1818-1832

2018

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LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials

Frontiers in pharmacology, 2023-02, Vol.14, p.1120911-1120911

2023

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Current HDAC Inhibitors in Clinical Trials

Chimia, 2022-05, Vol.76 (5), p.448

2022

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CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas

Frontiers in pharmacology, 2020-08, Vol.11, p.1230-1230

2020

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Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy

Nature communications, 2024-03, Vol.15 (1), p.2235-2235, Article 2235

2024

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Selenium-Containing Agents Acting on Cancer-A New Hope?

Pharmaceutics, 2022-12, Vol.15 (1), p.104

2022

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Molecular Docking Assessment of Cathinones as 5-HT2AR Ligands: Developing of Predictive Structure-Based Bioactive Conformations and Three-Dimensional Structure-Activity Relationships Models for Future Recognition of Abuse Drugs

Molecules (Basel, Switzerland), 2023-08, Vol.28 (17), p.6236

2023

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(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors

European journal of medicinal chemistry, 2016-07, Vol.117, p.292-300

2016

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Essential Oils from Mediterranean Plants Inhibit In Vitro Monocyte Adhesion to Endothelial Cells from Umbilical Cords of Females with Gestational Diabetes Mellitus

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7225

2023

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Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation

Science advances, 2020-04, Vol.6 (15), p.eaax2746

2020

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Pharmacological Activation of SIRT3 Modulates the Response of Cancer Cells to Acidic pH

Pharmaceuticals (Basel, Switzerland), 2024-06, Vol.17 (6), p.810

2024

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Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.973-985

2022

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Tranylcypromine‐Based LSD1 Inhibitors: Structure‐Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation

ChemMedChem, 2020-04, Vol.15 (7), p.643-658

2020

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Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells

Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3122

2020

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Retraction Note: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelialmesenchymal transition, migration, and on the pro-inflammatory phenotype

Clinical epigenetics, 2023-11, Vol.15 (1), p.1-179, Article 179

2023

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A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone

Journal of medicinal chemistry, 2009-01, Vol.52 (2), p.530-536

2009

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Screening of the activity of sixty essential oils against plasmodium early mosquito stages in vitro and machine learning analysis reveals new putative inhibitors of malaria parasites

International journal for parasitology -- drugs and drug resistance, 2023-12, Vol.23, p.87-93

2023

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Design, Synthesis, Antiviral Evaluation, and SAR Studies of New 1-(Phenylsulfonyl)-1H-Pyrazol−4-yl-Methylaniline Derivatives

Frontiers in chemistry, 2019-04, Vol.7, p.214-214

2019

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PD-L1 small-molecule modulators: A new hope in epigenetic-based multidrug cancer therapy?

Drug discovery today, 2023-02, Vol.28 (2), p.103435-103435, Article 103435

2023

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Targeting histone acetylation/deacetylation in parasites: an update (2017–2020)

Current opinion in chemical biology, 2020-08, Vol.57, p.65-74

2020

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RETRACTED ARTICLE: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype

Clinical epigenetics, 2019-12, Vol.11 (1), Article 173

2019

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Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1 H)-pyrazole derivatives

European journal of medicinal chemistry, 2008-10, Vol.43 (10), p.2262-2267

2008

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Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors

Current opinion in structural biology, 2023-10, Vol.82, p.102668, Article 102668

2023

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Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer

Current opinion in chemical biology, 2019-06, Vol.50, p.89-100

2019

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GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design

Green chemistry : an international journal and green chemistry resource : GC, 2023-03, Vol.25 (6), p.219-2169

2023

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Six Years (2012–2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2‐Pyridone Compounds

LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials

Current HDAC Inhibitors in Clinical Trials

CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas

Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy

Selenium-Containing Agents Acting on Cancer-A New Hope?

Molecular Docking Assessment of Cathinones as 5-HT2AR Ligands: Developing of Predictive Structure-Based Bioactive Conformations and Three-Dimensional Structure-Activity Relationships Models for Future Recognition of Abuse Drugs

(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors

Essential Oils from Mediterranean Plants Inhibit In Vitro Monocyte Adhesion to Endothelial Cells from Umbilical Cords of Females with Gestational Diabetes Mellitus

Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation

Pharmacological Activation of SIRT3 Modulates the Response of Cancer Cells to Acidic pH

Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

Tranylcypromine‐Based LSD1 Inhibitors: Structure‐Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation

Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells

Retraction Note: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelialmesenchymal transition, migration, and on the pro-inflammatory phenotype

A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone

Screening of the activity of sixty essential oils against plasmodium early mosquito stages in vitro and machine learning analysis reveals new putative inhibitors of malaria parasites

Design, Synthesis, Antiviral Evaluation, and SAR Studies of New 1-(Phenylsulfonyl)-1H-Pyrazol−4-yl-Methylaniline Derivatives

PD-L1 small-molecule modulators: A new hope in epigenetic-based multidrug cancer therapy?

Targeting histone acetylation/deacetylation in parasites: an update (2017–2020)

RETRACTED ARTICLE: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype

Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1 H)-pyrazole derivatives

Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors

Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer

GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design

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