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DNA targeting specificity of RNA-guided Cas9 nucleases

Nature biotechnology, 2013-09, Vol.31 (9), p.827-832

2013

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COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Molecular therapy. Nucleic acids, 2014-12, Vol.3 (12), p.e214-e214, Article e214

2014

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An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

Nucleic acids research, 2014-04, Vol.42 (6), p.e42

2014

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Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing

Cell reports (Cambridge), 2014-04, Vol.7 (1), p.293-305

2014

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CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

Scientific reports, 2017-12, Vol.7 (1), p.17472-17472, Article 17472

2017

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CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

Nucleic acids research, 2013-11, Vol.41 (20), p.9584

2013

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SAPTA: a new design tool for improving TALE nuclease activity

Nucleic acids research, 2014-04, Vol.42 (6), p.e47

2014

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Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes

Scientific reports, 2015-07, Vol.5 (1), p.10777-10777, Article 10777

2015

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Quantifying on- and off-target genome editing

Trends in biotechnology (Regular ed.), 2015-02, Vol.33 (2), p.132-140

2015

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Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

Molecular therapy, 2016-03, Vol.24 (3), p.475-487

2016

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TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

Nucleic acids research, 2014-06, Vol.42 (10), p.6762

2014

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TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

Molecular therapy. Nucleic acids, 2016-01, Vol.5 (1), p.e273-e273, Article e273

2016

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Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector

Current gene therapy, 2014-01, Vol.14 (5), p.365

2014

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Nanomedicine: Tiny Particles and Machines Give Huge Gains

Annals of biomedical engineering, 2014-02, Vol.42 (2), p.243-259

2014

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Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

Scientific reports, 2020-05, Vol.10 (1), p.7500-7500, Article 7500

2020

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Clinical trials-in-a-dish: Different inter-individual drug responses for calcium handling and electrophysiology in a cohort of hiPSC-derived cardiomyocytes

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models

Methods in molecular biology (Clifton, N.J.), 2014, Vol.1114, p.371

2014

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682. Applied In Silico Engineering of Factor VIII-AAV Transgene Cassettes

Molecular therapy, 2015-05, Vol.23, p.S271-S272

2015

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Leveraging genetic diversity in vitro: Evolution or revolution in cardiac safety assessment?

Journal of pharmacological and toxicological methods, 2018-09, Vol.93, p.163-163

2018

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Strategies to Determine Off-Target Effects of Engineered Nucleases

Genome Editing, 2016, Vol.895, p.187-222

2016

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Quantifying Genome Editing Outcomes at Endogenous Loci using SMRT Sequencing

Cell reports (Cambridge), 2014-03, Vol.7 (1), p.293-305

2014

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Enhanced endothelial cell functions on rosette nanotube-coated titanium vascular stents

International journal of nanomedicine, 2009-01, Vol.4 (default), p.91-97

2009

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Improved detection of compound arrhythmogenicity in 2D cardiac stem cell models via advanced maturation strategies

Journal of pharmacological and toxicological methods, 2021-09, Vol.111, p.107028, Article 107028

2021

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DNA targeting specificity of RNA-guided Cas9 nucleases

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing

CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

SAPTA: a new design tool for improving TALE nuclease activity

Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes

Quantifying on- and off-target genome editing

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector

Nanomedicine: Tiny Particles and Machines Give Huge Gains

Author Correction: CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

Clinical trials-in-a-dish: Different inter-individual drug responses for calcium handling and electrophysiology in a cohort of hiPSC-derived cardiomyocytes

Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models

682. Applied In Silico Engineering of Factor VIII-AAV Transgene Cassettes

Leveraging genetic diversity in vitro: Evolution or revolution in cardiac safety assessment?

Strategies to Determine Off-Target Effects of Engineered Nucleases

Quantifying Genome Editing Outcomes at Endogenous Loci using SMRT Sequencing

Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions

Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions

Enhanced endothelial cell functions on rosette nanotube-coated titanium vascular stents

Improved detection of compound arrhythmogenicity in 2D cardiac stem cell models via advanced maturation strategies

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