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Critically evaluating sweet taste receptor expression and signaling through a molecular pharmacology lens

The FEBS journal, 2021-04, Vol.288 (8), p.2660-2672

2021

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Expression of adrenoceptor subtypes in preterm piglet heart is different to term heart

PloS one, 2014-03, Vol.9 (3), p.e92167-e92167

2014

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Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?

Trends in endocrinology and metabolism, 2022-07, Vol.33 (7), p.481-492

2022

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Characterisation of bis(4-aminoquinoline)s as α1A adrenoceptor allosteric modulators

European journal of pharmacology, 2022-02, Vol.916, p.174659-174659, Article 174659

2022

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Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease

Chemical senses, 2023-01, Vol.48

2023

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Low-Molecular-Weight Peptidic and Cyclic Antagonists of the Receptor for the Complement Factor C5a

Journal of medicinal chemistry, 1999-06, Vol.42 (11), p.1965-1974

1999

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A novel structural framework for α(1A/D)-adrenoceptor selective antagonists identified using subtype selective pharmacophores

PloS one, 2011-05, Vol.6 (5), p.e19695-e19695

2011

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Orphan receptor GPR37L1 remains unliganded

Nature chemical biology, 2021-04, Vol.17 (4), p.383-386

2021

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Homobivalent Conjugation Increases the Allosteric Effect of 9-aminoacridine at the α1-Adrenergic Receptors

Molecular pharmacology, 2017-02, Vol.91 (2), p.135-144

2017

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Glucocorticoid exposure and tissue gene expression of 11β HSD-1, 11β HSD-2, and glucocorticoid receptor in a porcine model of differential fetal growth

Reproduction (Cambridge, England), 2007-03, Vol.133 (3), p.653-661

2007

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Template selection and refinement considerations for modelling aminergic GPCR-ligand complexes

Journal of molecular graphics & modelling, 2017-09, Vol.76, p.488-503

2017

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Design, Synthesis, and Evaluation of N- and C‑Terminal Protein Bioconjugates as G Protein-Coupled Receptor Agonists

Bioconjugate chemistry, 2018-02, Vol.29 (2), p.403-409

2018

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An aspartate in the second extracellular loop of the α(1B) adrenoceptor regulates agonist binding

European journal of pharmacology, 2014-06, Vol.733, p.90-96

2014

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Pharmacological characterization of antagonists of the C5a receptor

British journal of pharmacology, 1999-12, Vol.128 (7), p.1461-1466

1999

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5-HT1A receptor pharmacophores to screen for off-target activity of α1-adrenoceptor antagonists

Journal of computer-aided molecular design, 2013-04, Vol.27 (4), p.305-319

2013

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α1-Adrenoceptor and serotonin 5-HT1A receptor affinity of homobivalent 4-aminoquinoline compounds: An investigation of the effect of linker length

Biochemical pharmacology, 2013-05, Vol.85 (10), p.1534-1541

2013

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Effects of a new C5a receptor antagonist on C5a‐ and endotoxin‐ induced neutropenia in the rat

British journal of pharmacology, 1999-02, Vol.126 (3), p.551-554

1999

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Human α1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines

Bioorganic & medicinal chemistry, 2014-11, Vol.22 (21), p.5910-5916

2014

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Placental transport of leucine in a porcine model of low birth weight

Reproduction (Cambridge, England), 2004-08, Vol.128 (2), p.229-235

2004

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The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile

Reproduction (Cambridge, England), 2005-06, Vol.129 (6), p.757-763

2005

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A Novel Structural Framework for α1A/D-Adrenoceptor Selective Antagonists Identified Using Subtype Selective Pharmacophores

PloS one, 2011-05, Vol.6 (5), p.e19695

2011

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Transgenic α1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival

Cardiovascular research, 2006-09, Vol.71 (4), p.735-743

2006

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Genetic Enhancement of Ventricular Contractility Protects against Pressure-Overload-Induced Cardiac Dysfunction

Journal of molecular and cellular cardiology, 2004-11, Vol.37 (5), p.979-987

2004

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Small Molecular Probes for G-Protein-Coupled C5a Receptors: Conformationally Constrained Antagonists Derived from the C Terminus of the Human Plasma Protein C5a

Journal of medicinal chemistry, 1998-08, Vol.41 (18), p.3417-3425

1998

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Homobivalent Conjugation Increases the Allosteric Effect of 9-aminoacridine at the α 1 -Adrenergic Receptors

Molecular pharmacology, 2017-02, Vol.91 (2), p.135-144

2017

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Critically evaluating sweet taste receptor expression and signaling through a molecular pharmacology lens

Expression of adrenoceptor subtypes in preterm piglet heart is different to term heart

Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?

Characterisation of bis(4-aminoquinoline)s as α1A adrenoceptor allosteric modulators

Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease

Low-Molecular-Weight Peptidic and Cyclic Antagonists of the Receptor for the Complement Factor C5a

A novel structural framework for α(1A/D)-adrenoceptor selective antagonists identified using subtype selective pharmacophores

Orphan receptor GPR37L1 remains unliganded

Homobivalent Conjugation Increases the Allosteric Effect of 9-aminoacridine at the α1-Adrenergic Receptors

Glucocorticoid exposure and tissue gene expression of 11β HSD-1, 11β HSD-2, and glucocorticoid receptor in a porcine model of differential fetal growth

Template selection and refinement considerations for modelling aminergic GPCR-ligand complexes

Design, Synthesis, and Evaluation of N- and C‑Terminal Protein Bioconjugates as G Protein-Coupled Receptor Agonists

An aspartate in the second extracellular loop of the α(1B) adrenoceptor regulates agonist binding

Pharmacological characterization of antagonists of the C5a receptor

5-HT1A receptor pharmacophores to screen for off-target activity of α1-adrenoceptor antagonists

α1-Adrenoceptor and serotonin 5-HT1A receptor affinity of homobivalent 4-aminoquinoline compounds: An investigation of the effect of linker length

Effects of a new C5a receptor antagonist on C5a‐ and endotoxin‐ induced neutropenia in the rat

Human α1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines

Placental transport of leucine in a porcine model of low birth weight

The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile

A Novel Structural Framework for α1A/D-Adrenoceptor Selective Antagonists Identified Using Subtype Selective Pharmacophores

Transgenic α1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival

Genetic Enhancement of Ventricular Contractility Protects against Pressure-Overload-Induced Cardiac Dysfunction

Small Molecular Probes for G-Protein-Coupled C5a Receptors: Conformationally Constrained Antagonists Derived from the C Terminus of the Human Plasma Protein C5a

Homobivalent Conjugation Increases the Allosteric Effect of 9-aminoacridine at the α 1 -Adrenergic Receptors

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