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A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

The European respiratory journal, 2018-06, Vol.51 (6), p.1702638-1702638

2018

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Pharmacotherapy for Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia: Past, Present, and Future

Pharmaceuticals (Basel, Switzerland), 2023-03, Vol.16 (4), p.503

2023

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Sodium-coupled neutral amino acid transporter 1 (SNAT1) modulates L-citrulline transport and nitric oxide (NO) signaling in piglet pulmonary arterial endothelial cells

PloS one, 2014, Vol.9 (1), p.e85730

2014

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Impact of l‐citrulline on nitric oxide signaling and arginase activity in hypoxic human pulmonary artery endothelial cells

Pulmonary circulation, 2023-04, Vol.13 (2), p.e12221-n/a

2023

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Folic acid, either solely or combined with L‐citrulline, improves NO signaling and ameliorates chronic hypoxia‐induced pulmonary hypertension in newborn pigs

Physiological reports, 2021-11, Vol.9 (21), p.e15096-n/a

2021

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Plasma Asymmetric Dimethylarginine in Infants with Bronchopulmonary Dysplasia: A Promising Biomarker Despite Uncertain Pathogenic Significance

The Journal of pediatrics, 2015-02, Vol.166 (2), p.222-224

2015

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L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

Pulmonary circulation, 2021-04, Vol.11 (2), p.1-10

2021

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L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets

American journal of physiology. Lung cellular and molecular physiology, 2009-09, Vol.297 (3), p.L506-L511

2009

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Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review

Paediatric drugs, 2020-06, Vol.22 (3), p.279-293

2020

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Rescue Treatment with L-Citrulline Inhibits Hypoxia-Induced Pulmonary Hypertension in Newborn Pigs

American journal of respiratory cell and molecular biology, 2015-08, Vol.53 (2), p.255-264

2015

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Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

American journal of physiology. Lung cellular and molecular physiology, 2020-04, Vol.318 (4), p.L762-L772

2020

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L-citrulline provides a novel strategy for treating chronic pulmonary hypertension in newborn infants

Acta Paediatrica, 2014-10, Vol.103 (10), p.1019-1026

2014

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Pharmacokinetics of l-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

Paediatric drugs, 2023-01, Vol.25 (1), p.87-96

2023

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Multi-dose enteral L-citrulline administration in premature infants at risk of developing pulmonary hypertension associated with bronchopulmonary dysplasia

Journal of perinatology, 2024-02, Vol.44 (2), p.280-287

2024

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Tetrahydrobiopterin oral therapy recouples eNOS and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

American journal of physiology. Lung cellular and molecular physiology, 2016-10, Vol.311 (4), p.L743-L753

2016

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l‐Citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs

Pediatric pulmonology, 2020-10, Vol.55 (10), p.2762-2772

2020

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Reactive oxygen species modulate Na + -coupled neutral amino acid transporter 1 expression in piglet pulmonary arterial endothelial cells

American journal of physiology. Heart and circulatory physiology, 2019-04, Vol.316 (4), p.H911-H919

2019

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Pulmonary hypertension in the premature infant population: Analysis of echocardiographic findings and biomarkers

Pediatric pulmonology, 2018-03, Vol.53 (3), p.302-309

2018

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Reactive oxygen species-reducing strategies improve pulmonary arterial responses to nitric oxide in piglets with chronic hypoxia-induced pulmonary hypertension

Antioxidants & redox signaling, 2013-05, Vol.18 (14), p.1727-1738

2013

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Voltage-gated K+ channels at an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets

American journal of physiology. Lung cellular and molecular physiology, 2006-12, Vol.291 (6), p.L1169-L1176

2006

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Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs

American journal of physiology. Lung cellular and molecular physiology, 1998-04, Vol.274 (4), p.517-L526

1998

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NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets

American journal of physiology. Lung cellular and molecular physiology, 2009-10, Vol.297 (4), p.L596-L607

2009

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Prolonged hypoxia augments L-citrulline transport by System A in the newborn piglet pulmonary circulation

Cardiovascular research, 2012-08, Vol.95 (3), p.375-384

2012

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Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets

American journal of physiology. Heart and circulatory physiology, 2010-10, Vol.299 (4), p.H1190-H1204

2010

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Pulmonary Arterial Responses to Reactive Oxygen Species Are Altered in Newborn Piglets With Chronic Hypoxia-Induced Pulmonary Hypertension

Pediatric research, 2011-08, Vol.70 (2), p.136-141

2011

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A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

Pharmacotherapy for Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia: Past, Present, and Future

Sodium-coupled neutral amino acid transporter 1 (SNAT1) modulates L-citrulline transport and nitric oxide (NO) signaling in piglet pulmonary arterial endothelial cells

Impact of l‐citrulline on nitric oxide signaling and arginase activity in hypoxic human pulmonary artery endothelial cells

Folic acid, either solely or combined with L‐citrulline, improves NO signaling and ameliorates chronic hypoxia‐induced pulmonary hypertension in newborn pigs

Plasma Asymmetric Dimethylarginine in Infants with Bronchopulmonary Dysplasia: A Promising Biomarker Despite Uncertain Pathogenic Significance

L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets

Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review

Rescue Treatment with L-Citrulline Inhibits Hypoxia-Induced Pulmonary Hypertension in Newborn Pigs

Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

L-citrulline provides a novel strategy for treating chronic pulmonary hypertension in newborn infants

Pharmacokinetics of l-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

Multi-dose enteral L-citrulline administration in premature infants at risk of developing pulmonary hypertension associated with bronchopulmonary dysplasia

Tetrahydrobiopterin oral therapy recouples eNOS and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

l‐Citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs

Reactive oxygen species modulate Na + -coupled neutral amino acid transporter 1 expression in piglet pulmonary arterial endothelial cells

Pulmonary hypertension in the premature infant population: Analysis of echocardiographic findings and biomarkers

Reactive oxygen species-reducing strategies improve pulmonary arterial responses to nitric oxide in piglets with chronic hypoxia-induced pulmonary hypertension

Voltage-gated K+ channels at an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets

Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs

NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets

Prolonged hypoxia augments L-citrulline transport by System A in the newborn piglet pulmonary circulation

Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets

Pulmonary Arterial Responses to Reactive Oxygen Species Are Altered in Newborn Piglets With Chronic Hypoxia-Induced Pulmonary Hypertension

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