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Voltage-gated sodium channels assemble and gate as dimers

Nature communications, 2017-12, Vol.8 (1), p.2077-14, Article 2077

2017

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Circadian rhythms govern cardiac repolarization and arrhythmogenesis

Nature (London), 2012-02, Vol.483 (7387), p.96-99

2012

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KChIP2 is a core transcriptional regulator of cardiac excitability

eLife, 2017-03, Vol.6

2017

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A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo

PloS one, 2012-08, Vol.7 (8), p.e42120

2012

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A common SCN5A polymorphism modulates the biophysical defects of SCN5A mutations

Heart rhythm, 2011-03, Vol.8 (3), p.455-462

2011

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Molecular determinants of pentamidine-induced hERG trafficking inhibition

Molecular pharmacology, 2012-02, Vol.81 (2), p.198-209

2012

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Antidepressant-induced Ubiquitination and Degradation of the Cardiac Potassium Channel hERG

The Journal of biological chemistry, 2011-09, Vol.286 (39), p.34413-34425

2011

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Role of the Cytosolic Chaperones Hsp70 and Hsp90 in Maturation of the Cardiac Potassium Channel hERG

Circulation research, 2003-06, Vol.92 (12), p.e87-e100

2003

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Mechanisms of Arsenic-Induced Prolongation of Cardiac Repolarization

Molecular pharmacology, 2004-07, Vol.66 (1), p.33-44

2004

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Pentamidine-induced long QT syndrome and block of hERG trafficking

The Journal of pharmacology and experimental therapeutics, 2005-01, Vol.312 (1), p.316

2005

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Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking

The Journal of pharmacology and experimental therapeutics, 2007-02, Vol.320 (2), p.525

2007

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The Binding Site for Channel Blockers That Rescue Misprocessed Human Long QT Syndrome Type 2 ether-a-gogo-related Gene (HERG) Mutations

The Journal of biological chemistry, 2002-02, Vol.277 (7), p.4989-4998

2002

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Gap junction heterogeneity as mechanism for electrophysiologically distinct properties across the ventricular wall

American journal of physiology. Heart and circulatory physiology, 2010-03, Vol.298 (3), p.H787-H794

2010

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Ionic bases for electrical remodeling of the canine cardiac ventricle

American journal of physiology. Heart and circulatory physiology, 2013-08, Vol.305 (3), p.H410-H419

2013

Volltextzugriff (PDF)

Phosphoinositide Binding Differentially Regulates NHE1 Na+/H+ Exchanger-dependent Proximal Tubule Cell Survival

The Journal of biological chemistry, 2011-12, Vol.286 (49), p.42435-42445

2011

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Molecular Determinants of Dofetilide Block of HERG K+ Channels

Circulation research, 1998-02, Vol.82 (3), p.386-395

1998

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Intracellular Potassium Stabilizes Human Ether-Ã -go-go-Related Gene Channels for Export from Endoplasmic Reticulum

Molecular pharmacology, 2009-04, Vol.75 (4), p.927-937

2009

Volltextzugriff (PDF)

Dopamine Modulates Synaptic Transmission in the Nucleus of the Solitary Tract

Journal of neurophysiology, 2002-11, Vol.88 (5), p.2736-2744

2002

Volltextzugriff (PDF)

Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine

Naunyn-Schmiedeberg's archives of pharmacology, 2010-05, Vol.381 (5), p.385-400

2010

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Spermine and Spermidine as Gating Molecules for Inward Rectifier $K^+$ Channels

Science (American Association for the Advancement of Science), 1994-11, Vol.266 (5187), p.1068-1072

1994

Volltextzugriff (PDF)

Antimony-Based Antileishmanial Compounds Prolong the Cardiac Action Potential by an Increase in Cardiac Calcium Currents

Molecular pharmacology, 2006-04, Vol.69 (4), p.1216-1225

2006

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Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures

Canadian journal of cardiology, 2009-08, Vol.25 (8), p.455-462

2009

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Retention in the Endoplasmic Reticulum as a Mechanism of Dominant-negative Current Suppression in Human Long QT Syndrome

Journal of molecular and cellular cardiology, 2000-12, Vol.32 (12), p.2327-2337

2000

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Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity

The Journal of clinical investigation, 2018-03, Vol.128 (3), p.1043-1056

2018

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In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: Compound effects of hERG pore region mutation and SCN5A N-terminus variant

Heart rhythm, 2008-11, Vol.5 (11), p.1567-1574

2008

Volltextzugriff (PDF)

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Voltage-gated sodium channels assemble and gate as dimers

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

KChIP2 is a core transcriptional regulator of cardiac excitability

A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo

A common SCN5A polymorphism modulates the biophysical defects of SCN5A mutations

Molecular determinants of pentamidine-induced hERG trafficking inhibition

Antidepressant-induced Ubiquitination and Degradation of the Cardiac Potassium Channel hERG

Role of the Cytosolic Chaperones Hsp70 and Hsp90 in Maturation of the Cardiac Potassium Channel hERG

Mechanisms of Arsenic-Induced Prolongation of Cardiac Repolarization

Pentamidine-induced long QT syndrome and block of hERG trafficking

Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking

The Binding Site for Channel Blockers That Rescue Misprocessed Human Long QT Syndrome Type 2 ether-a-gogo-related Gene (HERG) Mutations

Gap junction heterogeneity as mechanism for electrophysiologically distinct properties across the ventricular wall

Ionic bases for electrical remodeling of the canine cardiac ventricle

Phosphoinositide Binding Differentially Regulates NHE1 Na+/H+ Exchanger-dependent Proximal Tubule Cell Survival

Molecular Determinants of Dofetilide Block of HERG K+ Channels

Intracellular Potassium Stabilizes Human Ether-Ã -go-go-Related Gene Channels for Export from Endoplasmic Reticulum

Dopamine Modulates Synaptic Transmission in the Nucleus of the Solitary Tract

Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine

Spermine and Spermidine as Gating Molecules for Inward Rectifier $K^+$ Channels

Antimony-Based Antileishmanial Compounds Prolong the Cardiac Action Potential by an Increase in Cardiac Calcium Currents

Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures

Retention in the Endoplasmic Reticulum as a Mechanism of Dominant-negative Current Suppression in Human Long QT Syndrome

Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity

In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: Compound effects of hERG pore region mutation and SCN5A N-terminus variant

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