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Dermatokinetics: Advances and Experimental Models, Focus on Skin Metabolism

Current drug metabolism, 2022-04, Vol.23 (5), p.340-354

2022

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Temporal transcriptomic analysis of human primary keratinocytes exposed to β-naphthoflavone highlights the protective efficacy of skin to environmental pollutants

Toxicology in vitro, 2020-06, Vol.65, p.104822, Article 104822

2020

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Layer-by-Layer Assembly of Nanosized Membrane Fractions for the Assessment of Cytochrome P450 Xenobiotic Metabolism

ACS omega, 2018-10, Vol.3 (10), p.12535-12544

2018

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Development of an innovative bioreactor to simulate cutaneous absorption and metabolism for risk assessment purposes

Toxicology letters, 2017-10, Vol.280, p.S257-S257

2017

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Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay

Mutation research, 2009-08, Vol.678 (1), p.13-19

2009

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Comparative assessment of local tolerance of alcohols commonly used in alcohol-based hand rubs for hand hygiene

Toxicology in vitro, 2017-10, Vol.44, p.142-153

2017

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Preclinical Study of the Novel Vascular Occluding Agent, WST11, for Photodynamic Therapy of the Canine Prostate

The Journal of urology, 2011-07, Vol.186 (1), p.302-309

2011

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In vitro–in silico correlation in metabolism studies: Points to consider

Toxicology letters, 2014-09, Vol.229, p.S160-S160

2014

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Animal-free studies in cosmetic ingredient industry: Perspective and strategy after a 10-year experience

Toxicology letters, 2013-08, Vol.221, p.S219-S219

2013

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Effects of rhein on human articular chondrocytes in alginate beads

Biochemical pharmacology, 2003-02, Vol.65 (3), p.377-388

2003

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Evaluation of the New Photosensitizer Stakel (WST-11) for Photodynamic Choroidal Vessel Occlusion in Rabbit and Rat Eyes

Investigative ophthalmology & visual science, 2008-04, Vol.49 (4), p.1633-1644

2008

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Pharmacokinetics of tenatoprazole, a novel proton pump inhibitor, in healthy male Caucasian volunteers

Gastroenterology (New York, N.Y. 1943), 2003-04, Vol.124 (4), p.A231-A231

2003

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Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways

Clinical and experimental rheumatology, 2007-07, Vol.25 (4), p.546

2007

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Selection of dosing regimen with WST11 by Monte Carlo simulations, using PK data collected after single IV administration in healthy subjects and population PK modeling

Journal of pharmaceutical sciences, 2007-12, Vol.96 (12), p.3444-3456

2007

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Skin irritation using VitroDerm model for the personal care products classification: Internal validation process

Toxicology letters, 2013-08, Vol.221, p.S160-S161

2013

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Characterization of the inhibitory activity of tenatoprazole on the gastric H +,K +-ATPase in vitro and in vivo

Biochemical pharmacology, 2006-03, Vol.71 (6), p.837-849

2006

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How to integrate safety pharmacology end-points during toxicological studies in non-human primates for biologics?

Toxicology letters, 2009-09, Vol.189, p.S259-S259

2009

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Rhein inhibits interleukin-1[beta]-induced activation of MEK/ERK pathway and DNA binding of NF-[kappa]B and AP-1 in chondrocytes cultured in hypoxia: A potential mechanism for its disease-modifying effect in osteoarthritis

Inflammation, 2003-08, Vol.27 (4), p.233

2003

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Rhein inhibits interleukin-1 beta-induced activation of MEK/ERK pathway and DNA binding of NF-kappa B and AP-1 in chondrocytes cultured in hypoxia: a potential mechanism for its disease-modifying effect in osteoarthritis

Inflammation, 2003-08, Vol.27 (4), p.233-246

2003

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S-TENATOPRAZOLE SODIUM: A PROMISING NEW PROTON PUMP INHIBITOR WITH A SAFE GENERAL PHARMACOLOGICAL PROFILE

Journal of pharmacological and toxicological methods, 2007-09, Vol.56 (2), p.e25-e25

2007

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Synthesis of quinone and xanthone analogs of rhein

Tetrahedron, 2001-10, Vol.57 (44), p.9131-9135

2001

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ChemInform Abstract: Synthesis of Quinone and Xanthone Analogues of Rhein

ChemInform, 2002-02, Vol.33 (7), p.no-no

2002

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Pharmacokinetics of tenatoprazole, a newly synthesized proton pump inhibitor, in healthy male Caucasian volunteers

Arzneimittel-Forschung, 2006-01, Vol.56 (1), p.33-39

2006

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Mycophenolate mofetil vs azathioprine for remission maintenance in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized controlled trial

JAMA : the journal of the American Medical Association, 2010-12, Vol.304 (21), p.2381

2010

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Structural Determinants of HIV-1 Nucleocapsid Protein for cTAR DNA Binding and Destabilization, and Correlation with Inhibition of Self-primed DNA Synthesis

Journal of molecular biology, 2005-05, Vol.348 (5), p.1113-1126

2005

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Dermatokinetics: Advances and Experimental Models, Focus on Skin Metabolism

Temporal transcriptomic analysis of human primary keratinocytes exposed to β-naphthoflavone highlights the protective efficacy of skin to environmental pollutants

Layer-by-Layer Assembly of Nanosized Membrane Fractions for the Assessment of Cytochrome P450 Xenobiotic Metabolism

Development of an innovative bioreactor to simulate cutaneous absorption and metabolism for risk assessment purposes

Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay

Comparative assessment of local tolerance of alcohols commonly used in alcohol-based hand rubs for hand hygiene

Preclinical Study of the Novel Vascular Occluding Agent, WST11, for Photodynamic Therapy of the Canine Prostate

In vitro–in silico correlation in metabolism studies: Points to consider

Animal-free studies in cosmetic ingredient industry: Perspective and strategy after a 10-year experience

Effects of rhein on human articular chondrocytes in alginate beads

Evaluation of the New Photosensitizer Stakel (WST-11) for Photodynamic Choroidal Vessel Occlusion in Rabbit and Rat Eyes

Pharmacokinetics of tenatoprazole, a novel proton pump inhibitor, in healthy male Caucasian volunteers

Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways

Selection of dosing regimen with WST11 by Monte Carlo simulations, using PK data collected after single IV administration in healthy subjects and population PK modeling

Skin irritation using VitroDerm model for the personal care products classification: Internal validation process

Characterization of the inhibitory activity of tenatoprazole on the gastric H +,K +-ATPase in vitro and in vivo

How to integrate safety pharmacology end-points during toxicological studies in non-human primates for biologics?

Rhein inhibits interleukin-1[beta]-induced activation of MEK/ERK pathway and DNA binding of NF-[kappa]B and AP-1 in chondrocytes cultured in hypoxia: A potential mechanism for its disease-modifying effect in osteoarthritis

Rhein inhibits interleukin-1 beta-induced activation of MEK/ERK pathway and DNA binding of NF-kappa B and AP-1 in chondrocytes cultured in hypoxia: a potential mechanism for its disease-modifying effect in osteoarthritis

S-TENATOPRAZOLE SODIUM: A PROMISING NEW PROTON PUMP INHIBITOR WITH A SAFE GENERAL PHARMACOLOGICAL PROFILE

Synthesis of quinone and xanthone analogs of rhein

ChemInform Abstract: Synthesis of Quinone and Xanthone Analogues of Rhein

Pharmacokinetics of tenatoprazole, a newly synthesized proton pump inhibitor, in healthy male Caucasian volunteers

Mycophenolate mofetil vs azathioprine for remission maintenance in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized controlled trial

Structural Determinants of HIV-1 Nucleocapsid Protein for cTAR DNA Binding and Destabilization, and Correlation with Inhibition of Self-primed DNA Synthesis

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