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Biocatalytic routes to anti-viral agents and their synthetic intermediates

Chemical Society reviews, 2021-02, Vol.5 (3), p.1968-29

2021

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Engineering the Active Site of an (S)‐Selective Amine Transaminase for Acceptance of Doubly Bulky Primary Amines

Advanced synthesis & catalysis, 2020-02, Vol.362 (4), p.812-821

2020

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Semi‐Synthetic Sialic Acid Probes for Challenging the Substrate Promiscuity of Enzymes in the Sialoconjugation Pathway

Advanced synthesis & catalysis, 2020-12, Vol.362 (23), p.5485-5495

2020

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Hydroxamate Assays for High‐Throughput Screening of Transketolase Libraries Against Arylated Substrates

Advanced synthesis & catalysis, 2023-11, Vol.365 (22), p.3861-3871

2023

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nanoDSF as screening tool for enzyme libraries and biotechnology development

The FEBS journal, 2019-01, Vol.286 (1), p.184-204

2019

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Biocatalysis: Ready to Master Increasing Complexity

Advanced synthesis & catalysis, 2019-06, Vol.361 (11), p.2373-2376

2019

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Transketolase Catalyzed Synthesis of N‐Aryl Hydroxamic Acids

Advanced synthesis & catalysis, 2022-02, Vol.364 (3), p.612-621

2022

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Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products

Angewandte Chemie (International ed.), 2018-08, Vol.57 (32), p.10153-10157

International ed. in English, 2018

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Modern Biocatalysis: Stereoselective and Environmentally Friendly Reactions

1. Aufl., 2009

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Enantioselective Synthesis of Pharmaceutically Relevant Bulky Arylbutylamines Using Engineered Transaminases

Advanced synthesis & catalysis, 2022-09, Vol.364 (17), p.2972-2981

2022

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An α2,3‐Sialyltransferase from Photobacterium phosphoreum with Broad Substrate Scope: Controlling Hydrolytic Activity by Directed Evolution

Chemistry : a European journal, 2020-09, Vol.26 (50), p.11614-11624

2020

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Cascade Biocatalysis: Integrating Stereoselective and Environmentally Friendly Reactions

Sergio Riva, Wolf-Dieter Fessner / Sergio Riva, Wolf-Dieter Fessner

1, 2014

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Aldolase‐Catalyzed Asymmetric Synthesis of N‐Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes

Advanced synthesis & catalysis, 2019-06, Vol.361 (11), p.2673-2687

2019

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Enzymatic Synthesis of Aliphatic Acyloins Catalyzed by Thermostable Transketolase

ChemCatChem, 2020-11, Vol.12 (22), p.5772-5779

2020

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Donor Promiscuity of a Thermostable Transketolase by Directed Evolution: Efficient Complementation of 1‐Deoxy‐d‐xylulose‐5‐phosphate Synthase Activity

Angewandte Chemie (International ed.), 2017-05, Vol.56 (19), p.5358-5362

International ed. in English, 2017

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One‐Pot Cascade Synthesis of (3S)‐Hydroxyketones Catalyzed by Transketolase via Hydroxypyruvate Generated in Situ from d‐Serine by d‐Amino Acid Oxidase

Advanced synthesis & catalysis, 2019-06, Vol.361 (11), p.2550-2558

2019

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Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose‐6‐phosphate Aldolase

Chemistry : a European journal, 2017-04, Vol.23 (21), p.5005-5009

2017

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Systems Biocatalysis: Development and engineering of cell-free “artificial metabolisms” for preparative multi-enzymatic synthesis

New biotechnology, 2015-12, Vol.32 (6), p.658-664

Fessner, Wolf-Dieter

2015

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Convergent in situ Generation of Both Transketolase Substrates via Transaminase and Aldolase Reactions for Sequential One‐Pot, Three‐Step Cascade Synthesis of Ketoses

ChemCatChem, 2020-02, Vol.12 (3), p.812-817

2020

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Illuminating structure and acyl donor sites of a physiological transglutaminase substrate from Streptomyces mobaraensis

Protein science, 2018-05, Vol.27 (5), p.910-922

2018

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2‐Deoxyribose‐5‐phosphate aldolase from Thermotoga maritima in the synthesis of a statin side‐chain precursor: characterization, modeling and optimization

Journal of chemical technology and biotechnology (1986), 2019-06, Vol.94 (6), p.1832-1842

2019

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Second‐Generation Engineering of a Thermostable Transketolase (TKGst) for Aliphatic Aldehyde Acceptors with Either Improved or Reversed Stereoselectivity

Chembiochem : a European journal of chemical biology, 2017-03, Vol.18 (5), p.455-459

2017

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Fluorescence-Based Kinetic Assay for High-Throughput Discovery and Engineering of Stereoselective ω-Transaminases

Advanced synthesis & catalysis, 2015-05, Vol.357 (8), p.1721-1731

2015

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Minimalist Protein Engineering of an Aldolase Provokes Unprecedented Substrate Promiscuity

ACS catalysis, 2016-03, Vol.6 (3), p.1848-1852

2016

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Direct Enzymatic Branch‐End Extension of Glycocluster‐Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity

Chemistry : a European journal, 2017-01, Vol.23 (7), p.1623-1633

2017

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Biocatalytic routes to anti-viral agents and their synthetic intermediates

Engineering the Active Site of an (S)‐Selective Amine Transaminase for Acceptance of Doubly Bulky Primary Amines

Semi‐Synthetic Sialic Acid Probes for Challenging the Substrate Promiscuity of Enzymes in the Sialoconjugation Pathway

Hydroxamate Assays for High‐Throughput Screening of Transketolase Libraries Against Arylated Substrates

nanoDSF as screening tool for enzyme libraries and biotechnology development

Biocatalysis: Ready to Master Increasing Complexity

Transketolase Catalyzed Synthesis of N‐Aryl Hydroxamic Acids

Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products

Modern Biocatalysis: Stereoselective and Environmentally Friendly Reactions

Enantioselective Synthesis of Pharmaceutically Relevant Bulky Arylbutylamines Using Engineered Transaminases

An α2,3‐Sialyltransferase from Photobacterium phosphoreum with Broad Substrate Scope: Controlling Hydrolytic Activity by Directed Evolution

Cascade Biocatalysis: Integrating Stereoselective and Environmentally Friendly Reactions

Aldolase‐Catalyzed Asymmetric Synthesis of N‐Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes

Enzymatic Synthesis of Aliphatic Acyloins Catalyzed by Thermostable Transketolase

Donor Promiscuity of a Thermostable Transketolase by Directed Evolution: Efficient Complementation of 1‐Deoxy‐d‐xylulose‐5‐phosphate Synthase Activity

One‐Pot Cascade Synthesis of (3S)‐Hydroxyketones Catalyzed by Transketolase via Hydroxypyruvate Generated in Situ from d‐Serine by d‐Amino Acid Oxidase

Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose‐6‐phosphate Aldolase

Systems Biocatalysis: Development and engineering of cell-free “artificial metabolisms” for preparative multi-enzymatic synthesis

Convergent in situ Generation of Both Transketolase Substrates via Transaminase and Aldolase Reactions for Sequential One‐Pot, Three‐Step Cascade Synthesis of Ketoses

Illuminating structure and acyl donor sites of a physiological transglutaminase substrate from Streptomyces mobaraensis

2‐Deoxyribose‐5‐phosphate aldolase from Thermotoga maritima in the synthesis of a statin side‐chain precursor: characterization, modeling and optimization

Second‐Generation Engineering of a Thermostable Transketolase (TKGst) for Aliphatic Aldehyde Acceptors with Either Improved or Reversed Stereoselectivity

Fluorescence-Based Kinetic Assay for High-Throughput Discovery and Engineering of Stereoselective ω-Transaminases

Minimalist Protein Engineering of an Aldolase Provokes Unprecedented Substrate Promiscuity

Direct Enzymatic Branch‐End Extension of Glycocluster‐Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity

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