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Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy

Human gene therapy, 2014-03, Vol.25 (3), p.180-188

2014

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Clinical Considerations for Capsid Choice in the Development of Liver-Targeted AAV-Based Gene Transfer

Molecular therapy. Methods & clinical development, 2019-12, Vol.15, p.170-178

2019

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Cell-Based Tracers as Trojan Horses for Image-Guided Surgery

International journal of molecular sciences, 2021-01, Vol.22 (2), p.755

2021

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Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates

Blood advances, 2019-09, Vol.3 (17), p.2632-2641

2019

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Successful Repeated Hepatic Gene Delivery in Mice and Non-human Primates Achieved by Sequential Administration of AAV5 ch and AAV1

Molecular therapy, 2017-08, Vol.25 (8), p.1831-1842

2017

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Enhanced Factor IX Activity following Administration of AAV5-R338L “Padua” Factor IX versus AAV5 WT Human Factor IX in NHPs

Molecular therapy. Methods & clinical development, 2019-12, Vol.15, p.221-231

2019

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Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses

Arteriosclerosis, thrombosis, and vascular biology, 2006-10, Vol.26 (10), p.2288-2288

2006

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Adeno-associated virus mediated delivery of Tregitope 167 ameliorates experimental colitis

World journal of gastroenterology : WJG, 2012-08, Vol.18 (32), p.4288-4299

2012

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Recombinant AAV Integration Is Not Associated With Hepatic Genotoxicity in Nonhuman Primates and Patients

Molecular therapy, 2016-06, Vol.24 (6), p.1100-1105

2016

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Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease

Human vaccines & immunotherapeutics, 2012-10, Vol.8 (10), p.1459-1464

2012

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Murine CD4⁺CD25⁻ cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivo

BMC gastroenterology, 2012-12, Vol.12 (1), p.172-172, Article 172

2012

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Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial

Gene therapy, 2013-04, Vol.20 (4), p.361-369

2013

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Current use of benzodiazepines in anxiety disorders

Current opinion in psychiatry, 2009-01, Vol.22 (1), p.90-95

2009

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Immune Responses to AAV-Vectors, the Glybera Example from Bench to Bedside

Frontiers in immunology, 2014, Vol.5, p.82-82

2014

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701. Successful In Vivo Re-Administration of AAV with the Use of Two-Step AAV Injection

Molecular therapy, 2016-05, Vol.24, p.S277-S277

2016

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VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis

European journal of cancer (1990), 2008-09, Vol.44 (13), p.1904-1913

2008

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Therapeutic hFIX Activity Achieved after Single AAV5-hFIX Treatment in Hemophilia B Patients and NHPs with Pre-existing Anti-AAV5 NABs

Molecular therapy. Methods & clinical development, 2019-09, Vol.14, p.27-36

2019

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THU-365-Adeno-associated virus-serotype-specific transduction patterns in mice and non-human primates liver tissue: Implications for therapeutic efficacy

Journal of hepatology, 2019-04, Vol.70 (1), p.e314-e315

2019

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Seroprevalence of Pre-Existing Nabs Against AAV1, 2, 5, 6 and 8 in South African Hemophilia B Patient Population

Blood, 2019-11, Vol.134 (Supplement_1), p.3353-3353

2019

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

Nature (London), 1996-04, Vol.380 (6573), p.435-439

1996

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424. AAV Re-Administration Following Pediatric Application: Effect of Age at First Administration

Molecular therapy, 2016-05, Vol.24, p.S168-S168

2016

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Successful Repeated Hepatic Gene Delivery in Mice and Non-human Primates Achieved by Sequential Administration of AAV5ch and AAV1

Molecular therapy, 2017-08, Vol.25 (8), p.1831-1842

2017

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THU-363-Lipid nanoparticle pre-treatment improves adeno-associated virus diffusion in the primate liver and enables an increase of therapeutic transgene expression

Journal of hepatology, 2019-04, Vol.70 (1), p.e313-e314

2019

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Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

The Journal of immunology (1950), 2000-04, Vol.164 (8), p.4292-4300

2000

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Macrophage-specific inhibition of NF-κB activation reduces foam-cell formation

Atherosclerosis, 2007-06, Vol.192 (2), p.283-290

2007

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Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy

Clinical Considerations for Capsid Choice in the Development of Liver-Targeted AAV-Based Gene Transfer

Cell-Based Tracers as Trojan Horses for Image-Guided Surgery

Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates

Successful Repeated Hepatic Gene Delivery in Mice and Non-human Primates Achieved by Sequential Administration of AAV5 ch and AAV1

Enhanced Factor IX Activity following Administration of AAV5-R338L “Padua” Factor IX versus AAV5 WT Human Factor IX in NHPs

Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses

Adeno-associated virus mediated delivery of Tregitope 167 ameliorates experimental colitis

Recombinant AAV Integration Is Not Associated With Hepatic Genotoxicity in Nonhuman Primates and Patients

Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease

Murine CD4⁺CD25⁻ cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivo

Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial

Current use of benzodiazepines in anxiety disorders

Immune Responses to AAV-Vectors, the Glybera Example from Bench to Bedside

701. Successful In Vivo Re-Administration of AAV with the Use of Two-Step AAV Injection

VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis

Therapeutic hFIX Activity Achieved after Single AAV5-hFIX Treatment in Hemophilia B Patients and NHPs with Pre-existing Anti-AAV5 NABs

THU-365-Adeno-associated virus-serotype-specific transduction patterns in mice and non-human primates liver tissue: Implications for therapeutic efficacy

Seroprevalence of Pre-Existing Nabs Against AAV1, 2, 5, 6 and 8 in South African Hemophilia B Patient Population

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

424. AAV Re-Administration Following Pediatric Application: Effect of Age at First Administration

Successful Repeated Hepatic Gene Delivery in Mice and Non-human Primates Achieved by Sequential Administration of AAV5ch and AAV1

THU-363-Lipid nanoparticle pre-treatment improves adeno-associated virus diffusion in the primate liver and enables an increase of therapeutic transgene expression

Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

Macrophage-specific inhibition of NF-κB activation reduces foam-cell formation

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