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CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

Nature medicine, 2021-10, Vol.27 (10), p.1797-1805

2021

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Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies

Nature communications, 2024-02, Vol.15 (1), p.1583-1583, Article 1583

2024

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A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats

Scientific reports, 2020-11, Vol.10 (1), p.19168-19168, Article 19168

2020

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Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2

Frontiers in immunology, 2023-06, Vol.14, p.1119350-1119350

2023

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Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis

Frontiers in immunology, 2021-02, Vol.12, p.640070-640070

2021

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Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

mAbs, 2021-01, Vol.13 (1), p.1864084-1864084

2021

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Dual T-cell constant β chain (TRBC)1 and TRBC2 staining for the identification of T-cell neoplasms by flow cytometry

Blood cancer journal (New York), 2024-02, Vol.14 (1), p.34-34, Article 34

2024

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IκB Kinase ε Targets Interferon Regulatory Factor 1 in Activated T Lymphocytes

Molecular and Cellular Biology, 2014-03, Vol.34 (6), p.1054-1065

2014

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Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy

Journal for immunotherapy of cancer, 2023-06, Vol.11 (6), p.e006699

2023

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Optimised Method for the Production and Titration of Lentiviral Vectors Pseudotyped with the SARS-CoV-2 Spike

Bio-protocol, 2021-08, Vol.11 (16), p.e4194-e4194

2021

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Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

Nature medicine, 2019-09, Vol.25 (9), p.1408-1414

2019

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Trojan horses and guided missiles: targeted therapies in the war on arthritis

Nature reviews. Rheumatology, 2015-06, Vol.11 (6), p.328-337

2015

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Going with the flow: harnessing the power of the vasculature for targeted therapy in rheumatoid arthritis

Drug discovery today, 2016-01, Vol.21 (1), p.172-179

2016

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Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants

Journal of virology, 2021-09, Vol.95 (19), p.e0068521-e0068521

2021

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Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Molecular therapy, 2023-07, Vol.31 (7), p.2089-2104

2023

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Anti-CD21 Chimeric Antigen Receptor (CAR)-T Cells for T Cell Acute Lymphoblastic Leukaemia (T-ALL)

Blood, 2021-11, Vol.138 (Supplement 1), p.902-902

2021

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Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation

Arthritis & rheumatology (Hoboken, N.J.), 2015-10, Vol.67 (10), p.2661-2672

2015

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Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction

ACS chemical biology, 2024-02, Vol.19 (2), p.308-324

2024

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A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency

Antiviral research, 2021-10, Vol.194, p.105147-105147, Article 105147

2021

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Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Molecular therapy, 2024-02, Vol.32 (2), p.556-558

2024

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Abstract 1070: AUTO7: Anti-PSMA humanized CAR T-cell with improved persistence and resistance to tumor microenvironment for metastatic castration resistant prostate cancer (mCRPC)

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1070-1070

2020

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Abstract 2183: Targeting TRBC1 and 2 for the treatment of T cell lymphomas

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2183-2183

2020

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A High Sensitivity aCD22 CAR Combined with aCD19 CAR to Generate Dual Targeting CAR T Cells for the Treatment of r/r B-ALL

Blood, 2021-11, Vol.138 (Supplement 1), p.1710-1710

2021

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A1.54 Development of a novel bispecific therapeutic for rheumatoid arthritis

Annals of the rheumatic diseases, 2014-03, Vol.73 (Suppl 1), p.A23-A23

2014

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Structure Guided Engineering of Highly Specific Chimeric Antigen Receptors for the Treatment of T Cell Lymphomas

Blood, 2018-11, Vol.132 (Supplement 1), p.1661-1661

2018

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CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies

A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats

Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2

Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis

Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

Dual T-cell constant β chain (TRBC)1 and TRBC2 staining for the identification of T-cell neoplasms by flow cytometry

IκB Kinase ε Targets Interferon Regulatory Factor 1 in Activated T Lymphocytes

Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy

Optimised Method for the Production and Titration of Lentiviral Vectors Pseudotyped with the SARS-CoV-2 Spike

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

Trojan horses and guided missiles: targeted therapies in the war on arthritis

Going with the flow: harnessing the power of the vasculature for targeted therapy in rheumatoid arthritis

Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants

Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Anti-CD21 Chimeric Antigen Receptor (CAR)-T Cells for T Cell Acute Lymphoblastic Leukaemia (T-ALL)

Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation

Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction

A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency

Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Abstract 1070: AUTO7: Anti-PSMA humanized CAR T-cell with improved persistence and resistance to tumor microenvironment for metastatic castration resistant prostate cancer (mCRPC)

Abstract 2183: Targeting TRBC1 and 2 for the treatment of T cell lymphomas

A High Sensitivity aCD22 CAR Combined with aCD19 CAR to Generate Dual Targeting CAR T Cells for the Treatment of r/r B-ALL

A1.54 Development of a novel bispecific therapeutic for rheumatoid arthritis

Structure Guided Engineering of Highly Specific Chimeric Antigen Receptors for the Treatment of T Cell Lymphomas

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