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Contrasting effects of selective MAGL and FAAH inhibition on dopamine depletion and GDNF expression in a chronic MPTP mouse model of Parkinson's disease

Neurochemistry international, 2017-11, Vol.110, p.14-24

2017

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Simultaneous LC–MS/MS analysis of the biomarkers cAMP and cGMP in plasma, CSF and brain tissue

Journal of neuroscience methods, 2012-01, Vol.203 (2), p.338-343

2012

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Rapid analysis of GABA and glutamate in microdialysis samples using high performance liquid chromatography and tandem mass spectrometry

Journal of neuroscience methods, 2009-08, Vol.182 (1), p.78-84

2009

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Depletion of nucleus accumbens dopamine leads to impaired reward and aversion processing in mice: Relevance to motivation pathologies

Neuropharmacology, 2016-10, Vol.109, p.306-319

2016

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The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease

Neurobiology of disease, 2019-01, Vol.121, p.34-46

2019

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Evaluation of monoacylglycerol lipase as a therapeutic target in a transgenic mouse model of ALS

Neuropharmacology, 2017-09, Vol.124, p.157-169

2017

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Long-term effects of early-life environmental manipulations in rodents and primates: Potential animal models in depression research

Neuroscience and biobehavioral reviews, 2005, Vol.29 (4), p.649-674

2005

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A reduced concentration of brain interstitial amino acids is associated with depression in subarachnoid hemorrhage patients

Scientific reports, 2019-02, Vol.9 (1), p.2811-2811, Article 2811

2019

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Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

Synapse (New York, N.Y.), 2001-02, Vol.39 (2), p.167-174

2001

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In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species

Cell reports (Cambridge), 2019-11, Vol.29 (9), p.2862-2874.e9

2019

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Genetic ablation of tumor necrosis factor‐alpha (TNF‐α) and pharmacological inhibition of TNF‐synthesis attenuates MPTP toxicity in mouse striatum

Journal of neurochemistry, 2004-05, Vol.89 (4), p.822-833

2004

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Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l -DOPA-induced dyskinesia: A bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats

Neurobiology of disease, 2008-02, Vol.29 (2), p.210-220

2008

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Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice

Neurobiology of stress, 2018-02, Vol.8, p.42-56

2018

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Astrocyte-specific IKK2 activation in mice is sufficient to induce neuroinflammation but does not increase susceptibility to MPTP

Neurobiology of disease, 2012-12, Vol.48 (3), p.481-487

2012

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Long-term social isolation and medial prefrontal cortex: dopaminergic and cholinergic neurotransmission

Pharmacology, biochemistry and behavior, 2004-02, Vol.77 (2), p.371-379

2004

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Differential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia

PloS one, 2012-11, Vol.7 (11), p.e48783-e48783

2012

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Increased susceptibility of G-protein-coupled receptor 6 deficient mice to MPTP neurotoxicity

Neuroscience, 2016-11, Vol.337, p.218-223

2016

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CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis

PloS one, 2012-03, Vol.7 (3), p.e32664

2012

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Analysis of hydroxylation and nitration products of d-phenylalanine for in vitro and in vivo radical determination using high-performance liquid chromatography and photodiode array detection

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-05, Vol.877 (14-15), p.1501-1508

2009

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Dopamine-Dependent Neurodegeneration in Rats Induced by Viral Vector-Mediated Overexpression of the Parkin Target Protein, CDCrel-1

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.12438-12443

2003

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Whole-brain signatures of functional connectivity after bidirectional modulation of the dopaminergic system in mice

Neuropharmacology, 2020-11, Vol.178, p.108246-108246, Article 108246

2020

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G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease

Experimental neurology, 2014-07, Vol.257, p.1-9

2014

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Effect of a change in housing conditions on body weight, behavior and brain neurotransmitters in male C57BL/6J mice

Behavioural brain research, 2017-08, Vol.333, p.35-42

2017

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l-DOPA-induced dyskinesia in Parkinson's disease: a drug discovery perspective

Drug discovery today, 2010-10, Vol.15 (19), p.867-875

2010

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P376. Preclinical Pharmacological Characterization of the Selective NR2b Negative Allosteric Modulator BI 1569912 With Potential to Treat MDD

Biological psychiatry (1969), 2022-05, Vol.91 (9), p.S239-S239

2022

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Contrasting effects of selective MAGL and FAAH inhibition on dopamine depletion and GDNF expression in a chronic MPTP mouse model of Parkinson's disease

Simultaneous LC–MS/MS analysis of the biomarkers cAMP and cGMP in plasma, CSF and brain tissue

Rapid analysis of GABA and glutamate in microdialysis samples using high performance liquid chromatography and tandem mass spectrometry

Depletion of nucleus accumbens dopamine leads to impaired reward and aversion processing in mice: Relevance to motivation pathologies

The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease

Evaluation of monoacylglycerol lipase as a therapeutic target in a transgenic mouse model of ALS

Long-term effects of early-life environmental manipulations in rodents and primates: Potential animal models in depression research

A reduced concentration of brain interstitial amino acids is associated with depression in subarachnoid hemorrhage patients

Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species

Genetic ablation of tumor necrosis factor‐alpha (TNF‐α) and pharmacological inhibition of TNF‐synthesis attenuates MPTP toxicity in mouse striatum

Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l -DOPA-induced dyskinesia: A bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats

Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice

Astrocyte-specific IKK2 activation in mice is sufficient to induce neuroinflammation but does not increase susceptibility to MPTP

Long-term social isolation and medial prefrontal cortex: dopaminergic and cholinergic neurotransmission

Differential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia

Increased susceptibility of G-protein-coupled receptor 6 deficient mice to MPTP neurotoxicity

CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis

Analysis of hydroxylation and nitration products of d-phenylalanine for in vitro and in vivo radical determination using high-performance liquid chromatography and photodiode array detection

Dopamine-Dependent Neurodegeneration in Rats Induced by Viral Vector-Mediated Overexpression of the Parkin Target Protein, CDCrel-1

Whole-brain signatures of functional connectivity after bidirectional modulation of the dopaminergic system in mice

G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease

Effect of a change in housing conditions on body weight, behavior and brain neurotransmitters in male C57BL/6J mice

l-DOPA-induced dyskinesia in Parkinson's disease: a drug discovery perspective

P376. Preclinical Pharmacological Characterization of the Selective NR2b Negative Allosteric Modulator BI 1569912 With Potential to Treat MDD

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