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Identification of highly selective covalent inhibitors by phage display

Nature biotechnology, 2021-04, Vol.39 (4), p.490-498

2021

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Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway

Science advances, 2017-08, Vol.3 (8), p.e1700344

2017

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Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE

Scientific reports, 2020-04, Vol.10 (1), p.5830-5830, Article 5830

2020

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A structural perspective on the PP-loop ATP pyrophosphatase family

Critical reviews in biochemistry and molecular biology, 2018-11, Vol.53 (6), p.607-622

2018

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Molecular Regulation of the Polycomb Repressive-Deubiquitinase

International journal of molecular sciences, 2020-10, Vol.21 (21), p.7837

2020

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Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum

Biochemistry (Easton), 2018-09, Vol.57 (38), p.5513-5523

2018

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Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases

Scientific reports, 2020-10, Vol.10 (1), p.18123-18123, Article 18123

2020

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Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets

ADMET & DMPK, 2022-01, Vol.10 (2), p.107-114

Fellner, Matthias

2022

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Structures and Mechanisms of the Non-Heme Fe(II)- and 2‑Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist

Journal of the American Chemical Society, 2017-08, Vol.139 (34), p.11980-11988

2017

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Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (34), p.9074-9079

2017

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Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function

The Journal of biological chemistry, 2020-06, Vol.295 (24), p.8272-8284

2020

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Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase

The Journal of biological chemistry, 2018-08, Vol.293 (32), p.12303-12317

2018

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Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme

Biochemistry (Easton), 2024-04, Vol.63 (8), p.1038-1050

2024

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Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections

Journal of the American Chemical Society, 2024-03, Vol.146 (10), p.6880-6892

2024

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Nickel–pincer nucleotide cofactor

Current opinion in chemical biology, 2018-12, Vol.47, p.18-23

2018

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Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity

Biochemical journal, 2021-02, Vol.478 (3), p.669-684

2021

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Covalent isothiocyanate inhibitors of macrophage migration inhibitory factor as potential colorectal cancer treatments

ChemMedChem, 2024-07, p.e202400394

2024

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Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism

Biochemistry (Easton), 2018-06, Vol.57 (23), p.3244-3251

2018

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pH/glucose dual-responsive protein-based hydrogels with enhanced adhesive and antibacterial properties for diabetic wound healing

Food innovation and advances, 2024, Vol.3 (4), p.332-343

2024

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The Cysteine Dioxygenase Homologue from Pseudomonas aeruginosa Is a 3-Mercaptopropionate Dioxygenase

The Journal of biological chemistry, 2015-10, Vol.290 (40), p.24424-24437

2015

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Recurrent de novo missense variants across multiple histone H4 genes underlie a neurodevelopmental syndrome

American journal of human genetics, 2022-04, Vol.109 (4), p.750-758

2022

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The Cys-Tyr Cross-Link of Cysteine Dioxygenase Changes the Optimal pH of the Reaction without a Structural Change

Biochemistry (Easton), 2014-12, Vol.53 (50), p.7961-7968

2014

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Substrate and pH-Dependent Kinetic Profile of 3‑Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa

Biochemistry (Easton), 2016-03, Vol.55 (9), p.1362-1371

2016

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Unique cesium-binding sites in proteins, a case study with the sacrificial sulfur transferase LarE

JoLS, Journal of Life Sciences, 2021-03, Vol.3 (1)

Fellner, Matthias

2021

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Influence of cysteine 164 on active site structure in rat cysteine dioxygenase

Journal of biological inorganic chemistry, 2016-07, Vol.21 (4), p.501-510

2016

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Identification of highly selective covalent inhibitors by phage display

Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway

Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE

A structural perspective on the PP-loop ATP pyrophosphatase family

Molecular Regulation of the Polycomb Repressive-Deubiquitinase

Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum

Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases

Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets

Structures and Mechanisms of the Non-Heme Fe(II)- and 2‑Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist

Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE

Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function

Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase

Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme

Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections

Nickel–pincer nucleotide cofactor

Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity

Covalent isothiocyanate inhibitors of macrophage migration inhibitory factor as potential colorectal cancer treatments

Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism

pH/glucose dual-responsive protein-based hydrogels with enhanced adhesive and antibacterial properties for diabetic wound healing

The Cysteine Dioxygenase Homologue from Pseudomonas aeruginosa Is a 3-Mercaptopropionate Dioxygenase

Recurrent de novo missense variants across multiple histone H4 genes underlie a neurodevelopmental syndrome

The Cys-Tyr Cross-Link of Cysteine Dioxygenase Changes the Optimal pH of the Reaction without a Structural Change

Substrate and pH-Dependent Kinetic Profile of 3‑Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa

Unique cesium-binding sites in proteins, a case study with the sacrificial sulfur transferase LarE

Influence of cysteine 164 on active site structure in rat cysteine dioxygenase

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