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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Science translational medicine, 2019-07, Vol.11 (501)

2019

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Understanding acute burn injury as a chronic disease

Burns and trauma, 2019, Vol.7 (1), p.23-23

2019

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Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice

Nature communications, 2022-08, Vol.13 (1), p.4895-4895, Article 4895

2022

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Burn Injury Leads to Increased Long-Term Susceptibility to Respiratory Infection in both Mouse Models and Population Studies

PloS one, 2017-01, Vol.12 (1), p.e0169302-e0169302

2017

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Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

Nature protocols, 2020-05, Vol.15 (5), p.1628-1648

2020

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Tumor Infiltrating Effector Memory Antigen-Specific CD8 + T Cells Predict Response to Immune Checkpoint Therapy

Frontiers in immunology, 2020-11, Vol.11, p.584423-584423

2020

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Systemic long-term metabolic effects of acute non-severe paediatric burn injury

Scientific reports, 2022-07, Vol.12 (1), p.13043-13043, Article 13043

2022

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Identifying SETBP1 haploinsufficiency molecular pathways to improve patient diagnosis using induced pluripotent stem cells and neural disease modelling

Molecular autism, 2024-09, Vol.15 (1), p.42-16, Article 42

2024

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CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency

Stem cell research & therapy, 2022-02, Vol.13 (1), p.69-69, Article 69

2022

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Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response

Frontiers in immunology, 2020-07, Vol.11, p.1481-1481

2020

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IFNβ Is a Potent Adjuvant for Cancer Vaccination Strategies

Frontiers in immunology, 2021-09, Vol.12, p.735133-735133

2021

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Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

Stem cell research & therapy, 2023-12, Vol.14 (1), p.345-345, Article 345

2023

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Combination immune checkpoint blockade as an effective therapy for mesothelioma

Oncoimmunology, 2018-10, Vol.7 (10), p.e1494111-e1494111

2018

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Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes

Oncoimmunology, 2024, Vol.13 (1), p.2345859-2345859

2024

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Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

Oncoimmunology, 2020-01, Vol.9 (1), p.1684714

2020

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The role and therapeutic implications of T cells in cancer of the lung

Clinical & translational immunology, 2019, Vol.8 (8), p.e1076-n/a

2019

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Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy

Scientific data, 2024-05, Vol.11 (1), p.448-448, Article 448

2024

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Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes

Frontiers in immunology, 2020-04, Vol.11, p.542-542

2020

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CRISPR-Cas9-generated PTCHD1 2489T>G stem cells recapitulate patient phenotype when undergoing neural induction

HGG advances, 2024-01, Vol.5 (1), p.100257-100257, Article 100257

2024

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Cardiometabolic disease risk markers are increased following burn injury in children

Frontiers in public health, 2023-06, Vol.11, p.1105163-1105163

2023

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Corrigendum: Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response

Frontiers in immunology, 2020-10, Vol.11, p.598646-598646

2020

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The Immune Response to Skin Trauma Is Dependent on the Etiology of Injury in a Mouse Model of Burn and Excision

Journal of investigative dermatology, 2015-08, Vol.135 (8), p.2119-2128

2015

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Functional validation of variants of unknown significance using CRISPR gene editing and transcriptomics: A Kleefstra syndrome case study

Gene, 2022-05, Vol.821, p.146287-146287, Article 146287

2022

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Tumour draining lymph node-generated CD8 T cells play a role in controlling lung metastases after a primary tumour is removed but not when adjuvant immunotherapy is used

Cancer Immunology, Immunotherapy, 2021-11, Vol.70 (11), p.3249-3258

2021

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CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy

Cell reports (Cambridge), 2022-12, Vol.41 (13), p.111874, Article 111874

2022

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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Understanding acute burn injury as a chronic disease

Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice

Burn Injury Leads to Increased Long-Term Susceptibility to Respiratory Infection in both Mouse Models and Population Studies

Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

Tumor Infiltrating Effector Memory Antigen-Specific CD8 + T Cells Predict Response to Immune Checkpoint Therapy

Systemic long-term metabolic effects of acute non-severe paediatric burn injury

Identifying SETBP1 haploinsufficiency molecular pathways to improve patient diagnosis using induced pluripotent stem cells and neural disease modelling

CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency

Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response

IFNβ Is a Potent Adjuvant for Cancer Vaccination Strategies

Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

Combination immune checkpoint blockade as an effective therapy for mesothelioma

Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes

Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

The role and therapeutic implications of T cells in cancer of the lung

Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy

Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes

CRISPR-Cas9-generated PTCHD1 2489T>G stem cells recapitulate patient phenotype when undergoing neural induction

Cardiometabolic disease risk markers are increased following burn injury in children

Corrigendum: Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response

The Immune Response to Skin Trauma Is Dependent on the Etiology of Injury in a Mouse Model of Burn and Excision

Functional validation of variants of unknown significance using CRISPR gene editing and transcriptomics: A Kleefstra syndrome case study

Tumour draining lymph node-generated CD8 T cells play a role in controlling lung metastases after a primary tumour is removed but not when adjuvant immunotherapy is used

CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy

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