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Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents

European journal of medicinal chemistry, 2018-01, Vol.143, p.1463-1473

2018

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One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein

Pharmaceuticals (Basel, Switzerland), 2022-03, Vol.15 (3), p.376

2022

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Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α -amylase, and α -glucosidase: synthesis, molecular docking, and ADMET studies

Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2367128

2024

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Erratum to “Facile synthesis and in vitro anticancer evaluation of a new series of tetrahydroquinoline” [Heliyon 7(10) (October 2021) e08117]

Heliyon, 2024-01, Vol.10 (1), p.e23189-e23189, Article e23189

2024

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One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines

BMC chemistry, 2017-07, Vol.11 (1), p.1

2017

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Interception of Epoxide ring to quorum sensing system in Enterococcus faecalis and Staphylococcus aureus

AMB Express, 2023-11, Vol.13 (1), p.126-126, Article 126

2023

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Facile synthesis and in vitro anticancer evaluation of a new series of tetrahydroquinoline

Heliyon, 2021-10, Vol.7 (10), p.e08117, Article e08117

2021

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Secondary Metabolites of Actinomycetales as Potent Quorum Sensing Inhibitors Targeting Gram-Positive Pathogens: In Vitro and In Silico Study

Metabolites, 2022-03, Vol.12 (3), p.246

2022

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Rationale design, synthesis, cytotoxicity evaluation, and in silico mechanistic studies of novel 1,2,3-triazoles with potential anticancer activity

New journal of chemistry, 2022-06, Vol.46 (25), p.12206-12216

2022

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Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination studies against MRSA

Bioorganic chemistry, 2021-11, Vol.116, p.105339-105339, Article 105339

2021

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Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors

Journal of molecular structure, 2021-07, Vol.1236, p.130317, Article 130317

2021

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The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, VEGFR-2, and cell cycle of myeloid leukemia

Bioorganic chemistry, 2022-10, Vol.127, p.105968-105968, Article 105968

2022

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Erratum to: One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines

BMC chemistry, 2017-08, Vol.11 (1), p.1

2017

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Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies

Bioorganic chemistry, 2021-05, Vol.110, p.104803-104803, Article 104803

2021

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Synthetic coumarin derivatives with anticoagulation and antiplatelet aggregation inhibitory effects

Medicinal chemistry research, 2023-11, Vol.32 (11), p.2269-2278

2023

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In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors

Molecular diversity, 2022-02, Vol.26 (1), p.341-363

2022

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The role of current synthetic and possible plant and marine phytochemical compounds in the treatment of acne

RSC advances, 2024-07, Vol.14 (33), p.24287-24321

2024

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Isatin-Schiff's base and chalcone hybrids as chemically apoptotic inducers and EGFR inhibitors; design, synthesis, anti-proliferative activities and in silico evaluation

Journal of molecular structure, 2021-06, Vol.1234, p.130159, Article 130159

2021

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Design, synthesis, biological evaluation and molecular modeling of new coumarin derivatives as potent anticancer agents

Medicinal chemistry research, 2019-08, Vol.28 (8), p.1284-1297

2019

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In vivo screening and toxicity studies of indolinone incorporated thiosemicarbazone, thiazole and piperidinosulfonyl moieties as anticonvulsant agents

Bioorganic chemistry, 2021-11, Vol.116, p.105300, Article 105300

2021

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Development of new spiro[1,3]dithiine-4,11′-indeno[1,2-b]quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation

Bioorganic chemistry, 2023-02, Vol.131, p.106307-106307, Article 106307

2023

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In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies

Bioorganic chemistry, 2020-07, Vol.100, p.103951, Article 103951

2020

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Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies

Bioorganic chemistry, 2020-06, Vol.99, p.103841, Article 103841

2020

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Upregulation of BAX and caspase‐3, as well as downregulation of Bcl‐2 during treatment with indeno[1,2‐b]quinoxalin derivatives, mediated apoptosis in human cancer cells

Archiv der Pharmazie (Weinheim), 2022-05, Vol.355 (5), p.e2100454-n/a

2022

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In vivo and in vitro anti-inflammatory, antipyretic and ulcerogenic activities of pyridone and chromenopyridone derivatives, physicochemical and pharmacokinetic studies

Bioorganic chemistry, 2021-04, Vol.109, p.104742-104742, Article 104742

2021

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Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents

One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein

Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α -amylase, and α -glucosidase: synthesis, molecular docking, and ADMET studies

Erratum to “Facile synthesis and in vitro anticancer evaluation of a new series of tetrahydroquinoline” [Heliyon 7(10) (October 2021) e08117]

One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines

Interception of Epoxide ring to quorum sensing system in Enterococcus faecalis and Staphylococcus aureus

Facile synthesis and in vitro anticancer evaluation of a new series of tetrahydroquinoline

Secondary Metabolites of Actinomycetales as Potent Quorum Sensing Inhibitors Targeting Gram-Positive Pathogens: In Vitro and In Silico Study

Rationale design, synthesis, cytotoxicity evaluation, and in silico mechanistic studies of novel 1,2,3-triazoles with potential anticancer activity

Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination studies against MRSA

Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors

The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, VEGFR-2, and cell cycle of myeloid leukemia

Erratum to: One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines

Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies

Synthetic coumarin derivatives with anticoagulation and antiplatelet aggregation inhibitory effects

In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors

The role of current synthetic and possible plant and marine phytochemical compounds in the treatment of acne

Isatin-Schiff's base and chalcone hybrids as chemically apoptotic inducers and EGFR inhibitors; design, synthesis, anti-proliferative activities and in silico evaluation

Design, synthesis, biological evaluation and molecular modeling of new coumarin derivatives as potent anticancer agents

In vivo screening and toxicity studies of indolinone incorporated thiosemicarbazone, thiazole and piperidinosulfonyl moieties as anticonvulsant agents

Development of new spiro[1,3]dithiine-4,11′-indeno[1,2-b]quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation

In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies

Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies

Upregulation of BAX and caspase‐3, as well as downregulation of Bcl‐2 during treatment with indeno[1,2‐b]quinoxalin derivatives, mediated apoptosis in human cancer cells

In vivo and in vitro anti-inflammatory, antipyretic and ulcerogenic activities of pyridone and chromenopyridone derivatives, physicochemical and pharmacokinetic studies

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