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Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries

ACS combinatorial science, 2016-08, Vol.18 (8), p.438-443

2016

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Screening of copper and palladium-mediated reactions compatible with DNA-encoded chemical libraries

Helvetica chimica acta, 2019-04, Vol.102 (4)

2019

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A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

Advanced science, 2020-11, Vol.7 (22), p.2001970-n/a

2020

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Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody

Journal for immunotherapy of cancer, 2022-09, Vol.10 (9), p.e005282

2022

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Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries

ACS omega, 2023-07, Vol.8 (28), p.25090-25100

2023

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DNA‐encoded chemical libraries – achievements and remaining challenges

FEBS letters, 2018-06, Vol.592 (12), p.2168-2180

2018

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Large screening of DNA-compatible reaction conditions for Suzuki and Sonogashira cross-coupling reactions and for reverse amide bond formation

Bioorganic & medicinal chemistry, 2021-07, Vol.41, p.116206-116206, Article 116206

2021

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Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

Biochemical and biophysical research communications, 2020-12, Vol.533 (2), p.223-229

2020

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Discovery of Glutamate Carboxypeptidase III Ligands to Compete the Uptake of [177Lu]Lu-PSMA-617 in Healthy Organs

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.8247-8260

2024

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Screening of Three Transition Metal‐Mediated Reactions Compatible with DNA‐Encoded Chemical Libraries

Helvetica chimica acta, 2019-04, Vol.102 (4), p.n/a

2019

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Response to: GCP III is not the “off-target” for urea-based PSMA-ligands

European journal of nuclear medicine and molecular imaging, 2023-08, Vol.50 (10), p.2947-2949

2023

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Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics

European journal of nuclear medicine and molecular imaging, 2023-02, Vol.50 (3), p.957-961

2023

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Impact of library input on the hit discovery rate in DNA-encoded chemical library selections

Chemical science (Cambridge), 2023-11, Vol.14 (43), p.1226-1233

2023

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Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence

Chemistry : a European journal, 2021-06, Vol.27 (35), p.8985-8993

2021

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Permutational Encoding Strategy Accelerates HIT Validation from Single-Stranded DNA-Encoded Libraries

Bioconjugate chemistry, 2024-07, Vol.35 (7), p.1033-1043

2024

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Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands

Analytical chemistry (Washington), 2020-08, Vol.92 (15), p.10822-10829

2020

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Structural insights into the interaction of three Y-shaped ligands with PI3Kα

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (34), p.e2304071120-e2304071120

2023

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Specific Inhibitor of Placental Alkaline Phosphatase Isolated from a DNA-Encoded Chemical Library Targets Tumor of the Female Reproductive Tract

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15799-15809

2021

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DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target

Chemical science (Cambridge), 2024-05, Vol.15 (18), p.6789-6799

2024

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A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition

Nature chemistry, 2023-10, Vol.15 (10), p.1431-1443

2023

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Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications

Nature chemistry, 2021-06, Vol.13 (6), p.540-548

2021

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Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Blood, 2023-11, Vol.142 (Supplement 1), p.3435-3435

2023

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Impact of Ligand Size and Conjugation Chemistry on the Performance of Universal Chimeric Antigen Receptor T‑Cells for Tumor Killing

Bioconjugate chemistry, 2020-07, Vol.31 (7), p.1775-1783

2020

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Cover Feature: Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence (Chem. Eur. J. 35/2021)

Chemistry : a European journal, 2021-06, Vol.27 (35), p.8888-8888

2021

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Efficient combinatorial adaptor-mediated targeting of acute myeloid leukemia with CAR T-cells

Leukemia, 2024-09

2024

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Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries

Screening of copper and palladium-mediated reactions compatible with DNA-encoded chemical libraries

A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody

Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries

DNA‐encoded chemical libraries – achievements and remaining challenges

Large screening of DNA-compatible reaction conditions for Suzuki and Sonogashira cross-coupling reactions and for reverse amide bond formation

Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

Discovery of Glutamate Carboxypeptidase III Ligands to Compete the Uptake of [177Lu]Lu-PSMA-617 in Healthy Organs

Screening of Three Transition Metal‐Mediated Reactions Compatible with DNA‐Encoded Chemical Libraries

Response to: GCP III is not the “off-target” for urea-based PSMA-ligands

Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics

Impact of library input on the hit discovery rate in DNA-encoded chemical library selections

Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence

Permutational Encoding Strategy Accelerates HIT Validation from Single-Stranded DNA-Encoded Libraries

Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands

Structural insights into the interaction of three Y-shaped ligands with PI3Kα

Specific Inhibitor of Placental Alkaline Phosphatase Isolated from a DNA-Encoded Chemical Library Targets Tumor of the Female Reproductive Tract

DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target

A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition

Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Impact of Ligand Size and Conjugation Chemistry on the Performance of Universal Chimeric Antigen Receptor T‑Cells for Tumor Killing

Cover Feature: Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence (Chem. Eur. J. 35/2021)

Efficient combinatorial adaptor-mediated targeting of acute myeloid leukemia with CAR T-cells

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