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Notch signaling is activated by TLR stimulation and regulates macrophage functions

European journal of immunology, 2008-01, Vol.38 (1), p.174-183

2008

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Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice

The Journal of neuroscience, 2012-09, Vol.32 (38), p.13125-13136

2012

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Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

The Journal of neuroscience, 2010-05, Vol.30 (20), p.6862-6872

2010

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Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin

PloS one, 2010-05, Vol.5 (5), p.e10504

2010

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Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis

The Journal of biological chemistry, 2013-03, Vol.288 (10), p.7313-7325

2013

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Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia

The Journal of experimental medicine, 2013-07, Vol.210 (7), p.1311-1329

2013

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Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells

Frontiers in immunology, 2014, Vol.5, p.54-54

2014

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Binding of antitumor tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen to human serum albumin

Biochimie, 2011-07, Vol.93 (7), p.1089-1101

2011

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Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Aβ42 production

Nature medicine, 2005-05, Vol.11 (5), p.545-550

2005

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Notch1 augments NF-κB activity by facilitating its nuclear retention

The EMBO journal, 2006-01, Vol.25 (1), p.129-138

2006

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Optimization of Peptide Hydroxamate Inhibitors of Insulin-Degrading Enzyme Reveals Marked Substrate-Selectivity

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2246-2255

2013

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Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme

The Journal of biological chemistry, 2006-10, Vol.281 (41), p.30471-30478

2006

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Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

Nature immunology, 2005-07, Vol.6 (7), p.680-688

2005

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γ-Secretase Processing and Effects of γ-Secretase Inhibitors and Modulators on Long Aβ Peptides in Cells

The Journal of biological chemistry, 2014-02, Vol.289 (6), p.3276-3287

2014

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Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

The Journal of biological chemistry, 2010-02, Vol.285 (6), p.4224-4231

2010

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Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.4344-4353

2011

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Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes : NCCTG trial N01CC

Journal of clinical oncology, 2006-06, Vol.24 (18), p.2836-2841

2006

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A multigram chemical synthesis of the γ-secretase inhibitor LY411575 and its diastereoisomers

Bioorganic & medicinal chemistry, 2007-11, Vol.17 (22), p.6392-6395

2007

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Synthesis of a DOTA (Gd3+)-conjugate of proton-pump inhibitor pantoprazole for gastric wall imaging studies

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (9), p.2808-2811

2013

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A convenient synthesis of ( Z)-4-hydroxy- N-desmethyltamoxifen (endoxifen)

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3036-3038

2010

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NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

Frontiers in immunology, 2014, Vol.5, p.249-249

2014

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Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids

Tetrahedron letters, 2010-12, Vol.51 (49), p.6426-6428

2010

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A synthesis of the γ-secretase inhibitor BMS-708163

Tetrahedron letters, 2010-12, Vol.51 (50), p.6542-6544

2010

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Iothalamate Quantification by Tandem Mass Spectrometry to Measure Glomerular Filtration Rate

Clinical chemistry (Baltimore, Md.), 2010-04, Vol.56 (4), p.568-574

2010

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Synthesis of Acid-Cleavable Light Isotope-Coded Affinity Tags (ICAT-L) for Potential Use in Proteomic Expression Profiling Analysis

Bioconjugate chemistry, 2006-01, Vol.17 (1), p.248-254

2006

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Notch signaling is activated by TLR stimulation and regulates macrophage functions

Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice

Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin

Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis

Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia

Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells

Binding of antitumor tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen to human serum albumin

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Aβ42 production

Notch1 augments NF-κB activity by facilitating its nuclear retention

Optimization of Peptide Hydroxamate Inhibitors of Insulin-Degrading Enzyme Reveals Marked Substrate-Selectivity

Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

γ-Secretase Processing and Effects of γ-Secretase Inhibitors and Modulators on Long Aβ Peptides in Cells

Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin

Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes : NCCTG trial N01CC

A multigram chemical synthesis of the γ-secretase inhibitor LY411575 and its diastereoisomers

Synthesis of a DOTA (Gd3+)-conjugate of proton-pump inhibitor pantoprazole for gastric wall imaging studies

A convenient synthesis of ( Z)-4-hydroxy- N-desmethyltamoxifen (endoxifen)

NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids

A synthesis of the γ-secretase inhibitor BMS-708163

Iothalamate Quantification by Tandem Mass Spectrometry to Measure Glomerular Filtration Rate

Synthesis of Acid-Cleavable Light Isotope-Coded Affinity Tags (ICAT-L) for Potential Use in Proteomic Expression Profiling Analysis

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