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Notch1 augments NF-κB activity by facilitating its nuclear retention

The EMBO journal, 2006-01, Vol.25 (1), p.129-138

2006

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Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

Nature immunology, 2005-07, Vol.6 (7), p.680-688

2005

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Design and Chemical Synthesis of a Magnetic Resonance Contrast Agent with Enhanced in Vitro Binding, High Blood−Brain Barrier Permeability, and in Vivo Targeting to Alzheimer's Disease Amyloid Plaques

Biochemistry (Easton), 2004-05, Vol.43 (20), p.6064-6075

2004

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Synthesis of Acid-Cleavable Light Isotope-Coded Affinity Tags (ICAT-L) for Potential Use in Proteomic Expression Profiling Analysis

Bioconjugate chemistry, 2006-01, Vol.17 (1), p.248-254

2006

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A Concise, High Yield Synthesis of the Selective ECE-Inhibitor, CGS 35066

Synthetic communications, 2004-12, Vol.34 (5), p.775-782

2004

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Systemic and intestinal pharmacokinetics of methotrexate in patients with inflammatory bowel disease

Clinical pharmacology and therapeutics, 1999-01, Vol.65 (1), p.29-39

1999

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Efficacy of Glycoconjugated Dinitroanilines against Cryptosporidium parvum

The Journal of eukaryotic microbiology, 2003-07, Vol.50 (s1), p.550-552

2003

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Efficacy of Glycoconjugated Dinitroanilines against Cryptosporidium Parvum

The Journal of eukaryotic microbiology, 2003-11, Vol.50 (6), p.550-552

2003

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Synthesis of 1D-3-deoxy-, 1D-2,3-dideoxy-, and 1D-2,3,6-trideoxy-myo-inositol 1,4,5-trisphosphate from quebrachitol, their binding affinities, and calcium release activity

Journal of the American Chemical Society, 1993-06, Vol.115 (11), p.4429-4434

1993

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Inhibition of Recombinant Human Mitochondrial Aldehyde Dehydrogenase by Two Intermediate Metabolites of Disulfiram

Biochemical pharmacology, 1998-04, Vol.55 (7), p.1099-1103

1998

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Synthesis of (2 S)-2-amino-3-(1 H-4-indolyl)propanoic acid, a novel tryptophan analog for structural modification of bioactive peptides

Tetrahedron: asymmetry, 1998-12, Vol.9 (23), p.4127-4134

1998

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Synthesis of ( S)- and ( R)-enantiomers of p-(4-hydroxybenzoyl)phenylalanine, useful photoaffinity labeling probes for peptide–protein binding sites

Tetrahedron: asymmetry, 1998-07, Vol.9 (13), p.2333-2338

1998

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S-Methyl-N,N-Diethylthiocarbamate Sulfoxide and S-Methyl-N,N-Diethylthiocarbamate Sulfone, Two Candidates for the Active Metabolite of Disulfiram

Alcoholism, clinical and experimental research, 1996-05, Vol.20 (3), p.595-600

1996

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Efficient synthetic routes in fluorinated isosteres of inositol and their effects on cellular growth

Journal of the American Chemical Society, 1990-05, Vol.112 (11), p.4528-4531

1990

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Cloning of a cDNA for Short/Branched Chain Acyl-Coenzyme A Dehydrogenase from Rat and Characterization of Its Tissue Expression and Substrate Specificity

Archives of biochemistry and biophysics, 1996-07, Vol.331 (1), p.127-133

1996

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Comparative studies of the deprotection of various acid sensitive protecting groups with pyridinium p-toluenesulphonate

Tetrahedron letters, 1998-06, Vol.39 (23), p.4137-4138

1998

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Alzheimer's therapy: an approach to novel muscarinic ligands based upon the naturally occurring alkaloid himbacine

Bioorganic & medicinal chemistry letters, 1992-08, Vol.2 (8), p.797-802

1992

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Synthesis and Biological Activity of the D-3-Deoxy-3-fluoro and D-3-Chloro-3-deoxy Analogs of Phosphatidylinositol

Journal of organic chemistry, 1994-03, Vol.59 (5), p.963-971

1994

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Total synthesis of (+)-desepoxyasperdiol

Journal of the American Chemical Society, 1986-03, Vol.108 (5), p.1035-1039

1986

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Probing the topography of kainate recognition sites: Synthesis of a novel oxetane containing kainic acid analogue

Tetrahedron letters, 1990, Vol.31 (21), p.2967-2970

1990

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Copper(I)-catalyzed reactions of .beta.,.gamma.-epoxy alcohols with Grignard reagents

Journal of organic chemistry, 1983-11, Vol.48 (22), p.4131-4132

1983

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Synthesis of novel metabolically stable analogues of D- myo-inositol 1,4,5-trisphosphate

Tetrahedron letters, 1996-03, Vol.37 (12), p.1917-1920

1996

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Cellular pharmacology of D-3-azido-3-deoxy-myo-inositol, an inhibitor of phosphatidylinositol signaling having antiproliferative activity

Cancer chemotherapy and pharmacology, 1994-01, Vol.35 (1), p.71-79

1994

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Simplified analogs of himbacine displaying potent binding affinity for muscarinic receptors

Bioorganic & medicinal chemistry letters, 1993-06, Vol.3 (6), p.1247-1252

1993

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Cationic cyclopentaannelation: an efficient methylenomycin synthesis

Journal of the American Chemical Society, 1986-06, Vol.108 (12), p.3438-3442

1986

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Notch1 augments NF-κB activity by facilitating its nuclear retention

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

Design and Chemical Synthesis of a Magnetic Resonance Contrast Agent with Enhanced in Vitro Binding, High Blood−Brain Barrier Permeability, and in Vivo Targeting to Alzheimer's Disease Amyloid Plaques

Synthesis of Acid-Cleavable Light Isotope-Coded Affinity Tags (ICAT-L) for Potential Use in Proteomic Expression Profiling Analysis

A Concise, High Yield Synthesis of the Selective ECE-Inhibitor, CGS 35066

Systemic and intestinal pharmacokinetics of methotrexate in patients with inflammatory bowel disease

Efficacy of Glycoconjugated Dinitroanilines against Cryptosporidium parvum

Efficacy of Glycoconjugated Dinitroanilines against Cryptosporidium Parvum

Synthesis of 1D-3-deoxy-, 1D-2,3-dideoxy-, and 1D-2,3,6-trideoxy-myo-inositol 1,4,5-trisphosphate from quebrachitol, their binding affinities, and calcium release activity

Inhibition of Recombinant Human Mitochondrial Aldehyde Dehydrogenase by Two Intermediate Metabolites of Disulfiram

Synthesis of (2 S)-2-amino-3-(1 H-4-indolyl)propanoic acid, a novel tryptophan analog for structural modification of bioactive peptides

Synthesis of ( S)- and ( R)-enantiomers of p-(4-hydroxybenzoyl)phenylalanine, useful photoaffinity labeling probes for peptide–protein binding sites

S-Methyl-N,N-Diethylthiocarbamate Sulfoxide and S-Methyl-N,N-Diethylthiocarbamate Sulfone, Two Candidates for the Active Metabolite of Disulfiram

Efficient synthetic routes in fluorinated isosteres of inositol and their effects on cellular growth

Cloning of a cDNA for Short/Branched Chain Acyl-Coenzyme A Dehydrogenase from Rat and Characterization of Its Tissue Expression and Substrate Specificity

Comparative studies of the deprotection of various acid sensitive protecting groups with pyridinium p-toluenesulphonate

Alzheimer's therapy: an approach to novel muscarinic ligands based upon the naturally occurring alkaloid himbacine

Synthesis and Biological Activity of the D-3-Deoxy-3-fluoro and D-3-Chloro-3-deoxy Analogs of Phosphatidylinositol

Total synthesis of (+)-desepoxyasperdiol

Probing the topography of kainate recognition sites: Synthesis of a novel oxetane containing kainic acid analogue

Copper(I)-catalyzed reactions of .beta.,.gamma.-epoxy alcohols with Grignard reagents

Synthesis of novel metabolically stable analogues of D- myo-inositol 1,4,5-trisphosphate

Cellular pharmacology of D-3-azido-3-deoxy-myo-inositol, an inhibitor of phosphatidylinositol signaling having antiproliferative activity

Simplified analogs of himbacine displaying potent binding affinity for muscarinic receptors

Cationic cyclopentaannelation: an efficient methylenomycin synthesis

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